Hypertriglyceridemia News and Research

Hypertriglyceridemia refers to the condition where there are high blood levels of triglycerides, the most abundant fatty molecule in most organisms. It has been associated with atherosclerosis, even in the absence of hypercholesterolemia (high cholesterol levels). It can also lead to pancreatitis in excessive concentrations.

Interim data from Schering-Plough's narlaprevir Phase IIa study

3. November 2009 03:02

Schering-Plough Corporation today reported that interim results from an ongoing Phase IIa study of narlaprevir (SCH 900518), its investigational, once-daily protease inhibitor, demonstrated potent antiviral activity in treatment-naive patients with chronic hepatitis C virus (HCV) genotype 1. [More]

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Posted in: Drug Trial News | Disease/Infection News

Tags: Anemia, Angina, Angioedema, Anorexia, Anxiety, Arthritis, Blindness, Bone, Bone Marrow, Cancer, Cardiomyopathy, Cell, Cellulitis, Cirrhosis, Contraception, Creatinine, Depression, Dyspnea, Edema, Emphysema, Fibrosis, Gastroenteritis, Gout, Headache, Hepatitis C, Hepatology, Hyperglycemia, Hypersensitivity, Hyperthyroidism, Hypertriglyceridemia, Hypothyroidism, Insomnia, Liver Cancer, Lupus, Nausea, Neuropathy, Neutropenia, Pancreatitis, Peginterferon alfa, Pneumonia, Pregnancy, Psoriasis, Psychosis, Pulmonary Hypertension, Rheumatoid Arthritis, Ribavirin, Ritonavir, Sarcoidosis, Sepsis, Thalassemia, Thrombocytopenia, Thrombosis, Transient Ischemic Attack, Urticaria, Vasculitis, Virus, Vomiting, Weight Loss

Schering-Plough receives FDA complete response letter regarding PEGINTRON

31. October 2009 03:09

Schering-Plough Corp. announced today the U.S. Food and Drug Administration (FDA) has issued a complete response letter to the company's supplemental Biologics License Application regarding PEGINTRON® (pegylated interferon alfa-2b) for the adjuvant treatment of patients with stage III malignant melanoma after complete lymphadenectomy. [More]

c3fa1d4f-06bd-4b30-80ad-b27272ea5cd9|0|.0

Posted in: Drug Trial News | Medical Condition News

Tags: Anemia, Angina, Angioedema, Anorexia, Anxiety, Arthritis, Blindness, Bone, Bone Marrow, Cancer, Cardiomyopathy, Cell, Cellulitis, Cirrhosis, Contraception, Creatinine, Depression, Dyspnea, Edema, Emphysema, Fibrosis, Gastroenteritis, Gout, Headache, Hepatitis C, Hyperglycemia, Hypersensitivity, Hyperthyroidism, Hypertriglyceridemia, Hypothyroidism, Insomnia, Lupus, Melanoma, Nausea, Neuropathy, Neutropenia, Oncology, Pancreatitis, Pneumonia, Pregnancy, Psoriasis, Psychosis, Pulmonary Hypertension, Rheumatoid Arthritis, Ribavirin, Sarcoidosis, Sepsis, Thalassemia, Thrombocytopenia, Thrombosis, Transient Ischemic Attack, Urticaria, Vasculitis, Vomiting, Weight Loss

Impax Laboratories initiates patent challenge for TRICOR

30. October 2009 11:18

Impax Laboratories, Inc. today confirms that it has initiated a challenge of the patents listed by Abbott Laboratories in connection with its TRICOR® (fenofibrate) tablets, 48 mg and 145 mg. [More]

edc7fcb8-a187-4344-b51c-d7bde51ccbd3|0|.0

Posted in: Medical Patent News | Pharmaceutical News

Tags: Diet, Drug Delivery, Fenofibrate, Hypercholesterolemia, Hyperlipidemia, Hypertriglyceridemia, New Drug Application

Amarin selects Medpace as CRO for its Phase 3 AMR101 MARINE clinical study

19. October 2009 10:00

Amarin Corporation plc today announced that it has executed an agreement with Medpace, Inc. (‘Medpace’), a leading Contract Research Organization (CRO) with expertise in conducting clinical trials in cardiovascular and metabolic disease, to engage their services in the execution of its Phase 3 clinical trials with AMR101 in patients with very high triglyceride levels (the AMR101 MARINE Study) and mixed dyslipidemia. [More]

0af765e7-2554-46fa-9494-82d42a23bfd7|0|.0

Posted in: Drug Trial News | Medical Condition News

Tags: Biotechnology, Cardiovascular Disease, Cholesterol, Dyslipidemia, Hyperlipidemia, Hypertriglyceridemia, Lipoprotein, Myasthenia Gravis, Nervous System, Statin, Triglyceride

Amarin raises $70 million through private placement

19. October 2009 09:12

Amarin Corporation plc today announced it has closed its $70 million private placement. The transaction was led by existing investor, Fountain Healthcare Partners, on behalf of funds affiliated with other existing investors Sofinnova Ventures, Orbimed Advisors and Longitude Capital. The new investor group was led by funds affiliated with Abingworth LLP and included APG Asset Management, Great Point Partners, Tavistock Life Sciences Company and RA Capital. Cowen and Company, LLC acted as the exclusive placement agent for the transaction. [More]

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Posted in: Business / Finance

Tags: Cardiovascular Disease, Dyslipidemia, Hypertriglyceridemia, Myasthenia Gravis, Nervous System

Schering-Plough to present data on boceprevir at the AASLD 2009 Annual Meeting

19. October 2009 08:38

Schering-Plough today announced that data on boceprevir, an investigational hepatitis C virus (HCV) protease inhibitor, will be reported in an oral presentation at the American Association for the Study of Liver Diseases (AASLD) Annual Meeting in Boston, Oct. 30-Nov. 3. [More]

5a662e81-818c-4eef-9ba6-1ed80bf43082|0|.0

Posted in: Drug Trial News | Disease/Infection News

Tags: Anemia, Angina, Angioedema, Anorexia, Anxiety, Arthritis, Blindness, Bone, Bone Marrow, Cancer, Cardiomyopathy, Cell, Cellulitis, Cholesterol, Cirrhosis, Contraception, Creatinine, Depression, Dyspnea, Edema, Emphysema, Fibrosis, Gastroenteritis, Gout, Headache, Hepatitis C, Hyperglycemia, Hypersensitivity, Hyperthyroidism, Hypertriglyceridemia, Hypothyroidism, Insomnia, Lipoprotein, Liver Cancer, Lupus, Nausea, Neuropathy, Neutropenia, Pancreatitis, Peginterferon alfa, Pneumonia, Pregnancy, Psoriasis, Psychosis, Pulmonary Hypertension, Rheumatoid Arthritis, Ribavirin, Sarcoidosis, Sepsis, Thalassemia, Thrombocytopenia, Thrombosis, Transient Ischemic Attack, Transplant, Urticaria, Vasculitis, Virus, Vomiting, Weight Loss

FDA approves Daiichi Sankyo's sNDA for Welchol

7. October 2009 09:04

Daiichi Sankyo, Inc. (DSI) announced today that the U.S. Food and Drug Administration (FDA) has approved the supplemental new drug application (sNDA) for Welchol® (colesevelam HCl) to be used as an adjunct to diet and exercise for the reduction of elevated low-density lipoprotein cholesterol (LDL-C) in boys and postmenarchal girls, 10 to 17 years of age, with heterozygous familial hypercholesterolemia (heFH) alone or in combination with a statin after failing an adequate trial of diet therapy. [More]

8c182348-b930-454c-8dce-ef11934e8cc3|0|.0

Posted in: Pharmaceutical News

Tags: Atherosclerosis, Bone, Cancer, Cardiovascular Disease, CDC, Cholesterol, Constipation, Diabetes, Diabetes Mellitus, Diabetic Ketoacidosis, Diet, Dyslipidemia, Exercise, Gastroparesis, Headache, Hypercholesterolemia, Hyperlipidemia, Hypertriglyceridemia, Hypoglycemia, Insulin, Lipoprotein, Nausea, New Drug Application, Pancreatitis, Pregnancy, Rhinitis, Statin, Thiazolidinediones, Triglyceride, Type 1 Diabetes, Type 2 Diabetes, Vitamin K, Vomiting, Warfarin

Schering-Plough receives FDA recommendation approval for PEGINTRON

6. October 2009 02:15

Schering-Plough Corp. announced today that the U.S. Food and Drug Administration's (FDA) Oncologic Drugs Advisory Committee (ODAC) recommended approval by a vote of six to four for PEGINTRON® (pegylated interferon alfa-2b) in the adjuvant treatment of patients with Stage III malignant melanoma. [More]

2c85957a-8af0-43ed-8612-5a44c9ace7bf|1|4.0

Posted in: Medical Condition News | Pharmaceutical News

Tags: Anemia, Angina, Angioedema, Anorexia, Anxiety, Arthritis, Blindness, Bone, Bone Marrow, Cancer, Cardiomyopathy, Cell, Cellulitis, Cirrhosis, Contraception, Creatinine, Depression, Dyspnea, Edema, Emphysema, Fibrosis, Gastroenteritis, Gout, Headache, Hematology, Hepatitis C, Hyperglycemia, Hypersensitivity, Hyperthyroidism, Hypertriglyceridemia, Hypothyroidism, Insomnia, Lupus, Melanoma, Nausea, Neuropathy, Neutropenia, Oncology, Pancreatitis, Pneumonia, Pregnancy, Psoriasis, Psychosis, Pulmonary Hypertension, Rheumatoid Arthritis, Ribavirin, Sarcoidosis, Sepsis, Skin Cancer, Thalassemia, Thrombocytopenia, Thrombosis, Transient Ischemic Attack, Urticaria, Vasculitis, Vomiting, Weight Loss

Vitae receives 11Beta-HSD-1 program milestone payment from Boehringer Ingelheim

29. September 2009 09:52

Vitae Pharmaceuticals, Inc., an integrated discovery and development company, today announced that it has earned an $8 million milestone payment from Boehringer Ingelheim for achievement of a performance milestone in their 11beta-hydroxysteroid dehydrogenase (HSD)-1 diabetes and metabolic disease strategic alliance. [More]

81797805-deab-4b13-a1ef-0ee9b808922b|0|.0

Posted in: Drug Trial News | Medical Condition News

Tags: Cortisol, Diabetes, Hypertriglyceridemia, Insulin, Lipids, Metabolic Syndrome, Obesity, Steroid, Type 2 Diabetes

Pronova BioPharma receives the 2009 Frost & Sullivan Excellence in Financial & Risk Management Award

8. September 2009 06:11

The 2009 Frost & Sullivan Global Heart Health Ingredients Excellence in Financial & Risk Management Award is presented to Pronova BioPharma ASA. The company's first commercialised product is the first and only EU-and FDA-approved omega-3 derived prescription drug. Branded Omacor in Europe and Asia and Lovaza in the USA, the product is a prescribed adjunct to diet for the treatment of elevated levels of triglycerides in humans. [More]

c79e64a5-1004-4d74-84ed-b83731401749|0|.0

Posted in: Business / Finance | Pharmaceutical News

Tags: Atrial Fibrillation, Diet, Dyslipidemia, Heart Failure, Hypertriglyceridemia, Investment, Metabolism, Prescription Drug, Triglyceride

Is metabolic character different between men and women with gallstone disease?

20. April 2009 23:22

There are a cluster of metabolic syndrome, that include obesity, high level of fasting plasma glucose, hypertriglyceridemia and hypertension, which is closely associated with the increased morbidity and mortality caused by several of the most common diseases including diabetes, hypertension, cardiovascular diseases, cancer and gallstone disease. [More]

11a870bc-ffcd-44a9-aa62-fb4c76577423|0|.0

Posted in: Medical Research News

Tags: Cancer, Cholesterol, Diabetes, Estrogen, Gastroenterology, Hypertension (High Blood Pressure), Hypertriglyceridemia, Metabolic Syndrome, Obesity, Pregnancy

Missing link between fructose, insulin resistance found

2. April 2009 22:42

A new study in mice sheds light on the insulin resistance that can come from diets loaded with high-fructose corn syrup, a sweetener found in most sodas and many other processed foods. [More]

78988f66-7d30-42c1-85eb-5bcfbb49b208|0|.0

Posted in: Medical Research News

Tags: Cell Metabolism, Diabetes, Diet, Genetics, Hypertriglyceridemia, Insulin, Insulin Resistance, Lipids, Metabolic Syndrome, Metabolism, Type 2 Diabetes

In lab supplements of lipoic acid lower triglyceride levels

30. March 2009 23:05

Studies done with laboratory rats suggest that supplementation of their diet with lipoic acid had a significant effect in lowering triglycerides, which along with cholesterol levels and blood pressure are one of the key risk factors in cardiovascular disease. [More]

0ed89714-0e59-4bbe-a600-a5f4f3928916|0|.0

Posted in: Medical Research News

Tags: Alternative Medicine, Antioxidant, Atherosclerosis, Biochemistry, Blood Pressure, Cardiovascular Disease, Cholesterol, Diabetes, Diet, Dyslipidemia, Exercise, Fibrates, Hypertriglyceridemia, Prescription Drug, Triglyceride

High triglyceride levels common, often untreated among Americans

23. March 2009 22:24

High concentrations of blood fats known as triglycerides are common in the United States, according to a report in the March 23 issue of Archives of Internal Medicine. [More]

0adf6f02-fd7b-4758-966e-7a9f1436626c|0|.0

Posted in: Medical Research News

Tags: Cardiovascular Disease, Cholesterol, Diabetes, Education, Fenofibrate, Hypertriglyceridemia, Nutrition, Obesity, Pancreatitis, Triglyceride

Missing link between fructose, insulin resistance found

3. March 2009 22:11

A new study in mice sheds light on the insulin resistance that can come from diets loaded with high-fructose corn syrup, a sweetener found in most sodas and many other processed foods. [More]

74cd1a2a-e8ab-417d-8ab1-2f3bebb9be0d|0|.0

Posted in: Medical Research News

Tags: Cell Metabolism, Diabetes, Diet, Genetics, Hypertriglyceridemia, Insulin, Insulin Resistance, Lipids, Metabolic Syndrome, Metabolism, Type 2 Diabetes

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Hypertriglyceridemia News and Research

Interim data from Schering-Plough's narlaprevir Phase IIa study

Schering-Plough receives FDA complete response letter regarding PEGINTRON

Impax Laboratories initiates patent challenge for TRICOR

Amarin selects Medpace as CRO for its Phase 3 AMR101 MARINE clinical study

Amarin raises $70 million through private placement

Schering-Plough to present data on boceprevir at the AASLD 2009 Annual Meeting

FDA approves Daiichi Sankyo's sNDA for Welchol

Schering-Plough receives FDA recommendation approval for PEGINTRON

Vitae receives 11Beta-HSD-1 program milestone payment from Boehringer Ingelheim

Pronova BioPharma receives the 2009 Frost & Sullivan Excellence in Financial & Risk Management Award

Is metabolic character different between men and women with gallstone disease?

Missing link between fructose, insulin resistance found

In lab supplements of lipoic acid lower triglyceride levels

High triglyceride levels common, often untreated among Americans

Missing link between fructose, insulin resistance found

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Hypertriglyceridemia News and Research

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