Hypertrophic Cardiomyopathy News and Research

RSS

Hypertrophic cardiomyopathy is a condition that affects the heart’s ability to pump blood effectively due to the thickening (hypertrophy) of the heart muscle which becomes stiff as a result.

Collaborative research paves a new way to better health for patients with enlarged hearts

A University of Texas at Arlington multidisciplinary team will use a National Institutes of Health (NIH) grant to research new ways to improve the safety and effectiveness of medical procedures on patients with inoperable enlarged hearts.

24 Oct 2022

Expanding screening could help prevent sudden cardiac death in young people with HCM

Nearly nine in ten cases of sudden cardiac death (SCD) due to hypertrophic cardiomyopathy (HCM) in young people are preceded by symptoms, ECG abnormalities or a positive family history, according to a new study published this week in the open-access journal PLOS ONE by Erik Börjesson of Sahlgrenska University Hospital, Sweden, and colleagues.

14 Sep 2022

Study uncovers a key role for MKK3/6–p38γ/δ signaling pathway in cardiac hypertrophy

A study carried out by scientists at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) and led by Dr. Guadalupe Sabio has identified a key role for the MKK3/6–p38γ/δ signaling pathway in the development of cardiac hypertrophy.

16 Aug 2022

Revolutionary technology identifies molecular alterations in failing hearts at single-cell resolution

Imagine, if scientists had a map of the heart, so granular in its accuracy that it even profiled details of the heart at the cellular level.

8 Jul 2022

Consensus document offers recommendations on genetic testing for inherited cardiac diseases

When should patients and family members undergo genetic assessment for a heart condition? Find out in an international consensus document published in EP Europace, a journal of the European Society of Cardiology and presented at EHRA 2022, a scientific congress of the ESC.

4 Apr 2022

Extension study shows mavacamten’s efficacy and safety in treating hypertrophic cardiomyopathy

Use of mavacamten, a novel cardiac myosin inhibitor, to treat people with symptomatic obstructive hypertrophic cardiomyopathy (HCM), a condition that results in excess thickening of the heart muscle, resulted in continued benefits in patient quality of life and outcomes over an extended period of time, according to interim data from the EXPLORER-HCM extension study presented at the American College of Cardiology's 71st Annual Scientific Session.

3 Apr 2022

New drug shows promise in relieving symptoms associated with hypertrophic cardiomyopathy

A new drug shows promise in providing relief to cardiomyopathy patients experiencing shortness of breath, according to late-breaking research presented today at the American College of Cardiology (ACC) Scientific Session in Washington, D.C.

3 Apr 2022

Experimental drug for hypertrophic cardiomyopathy reduces the need for invasive procedures, trial shows

Findings from a Cleveland Clinic-led clinical trial showed that the use of an experimental drug in severely symptomatic, hypertrophic cardiomyopathy patients significantly reduced the need for invasive procedures.

2 Apr 2022

AI-ECG algorithms can enhance detection and treatment of hypertrophic cardiomyopathy

Hypertrophic cardiomyopathy (HCM) is a leading cause of sudden death in adolescents and initial detection is often difficult.

8 Mar 2022

Novel AI tool can spot difficult-to-diagnose cardiac conditions

Physician-scientists in the Smidt Heart Institute at Cedars-Sinai have created an artificial intelligence (AI) tool that can effectively identify and distinguish between two life-threatening heart conditions that are often easy to miss: hypertrophic cardiomyopathy and cardiac amyloidosis.

23 Feb 2022

Drug improved cardiac structure and function in patients with early-stage hypertrophic cardiomyopathy

Valsartan, an angiotensin II receptor blocker drug, delayed disease progression and improved cardiac structure and function in patients with early-stage hypertrophic cardiomyopathy, according to results from a recent clinical trial published in Nature Medicine.

16 Nov 2021

New AI technology for heart imaging could improve care for patients

A new artificial-intelligence technology for heart imaging can potentially improve care for patients, allowing doctors to examine their hearts for scar tissue while eliminating the need for contrast injections required for traditional cardiovascular magnetic resonance imaging (CMR).

1 Sep 2021

AHA special issue focuses on health disparities among racial, ethnic communities

Poverty and Black race were associated with higher rates of lower leg amputation among people with peripheral artery disease who live in metropolitan areas, according to new research published today in a special issue of the Journal of the American Heart Association, an open access journal of the American Heart Association.

25 Aug 2021

Infantile sudden death associated with a de novo genetic mutation in the SOS1 gene

A previously healthy infant who suffered aborted sudden cardiac death was found to have a de novo genetic mutation in the SOS1 gene.

17 Aug 2021

Return to play can be managed for athletes with genetic heart diseases, study suggests

Receiving the diagnosis of a genetic heart disease such as long QT syndrome, which can cause sudden cardiac death, has long been a game-ender for young athletes. But a 20-year study at Mayo Clinic following such athletes who were allowed to return to play suggests that the risks can be managed through a shared decision-making process.

27 Jul 2021

Study could help improve care for irregular heartbeats in patients with hypertrophic cardiomyopathy

New research will help doctors identify, treat and prevent potentially dangerous irregular heartbeats in patients with hypertrophic cardiomyopathy (HCM), a common heart condition in which the heart thickens and strains to pump blood.

15 Jul 2021

Review details clinical signs of SARS-CoV-2 infection in domestic and wild cats

Now, a new systematic review has been published in the journal Animals that focuses on the clinical symptoms in felines diagnosed with SARS-CoV-2 worldwide.

13 Jul 2021

AI ECG as a novel noninvasive approach to diagnosing cardiac injury in COVID-19 patients

A recent study discusses the efficacy of an AI-enhanced ECG technique that has been used to diagnose left ventricular dysfunction in COVID-19 patients.

17 Jun 2021

Leducq Foundation provides $7 million to support Cardiac Splicing as a Therapeutic Target project

Diverse messenger RNAs are produced in cells by “alternative splicing.” The Leducq Foundation is now supporting a transatlantic network dedicated to investigating this process in heart muscle cells and how changes in this process contribute to disease. Professor Michael Gotthardt of the MDC and Professor Leslie Leinwand of the University of Colorado Boulder are coordinating the project.

14 Jun 2021

Which biomarkers can help predict severe COVID-19?

The ability to detect potentially fatal illness early on in the course of the disease would enable a swift prioritization of these high-risk individuals for treatment. A new preprint on the medRxiv* server presents an array of biomarkers that may help achieve this laudable goal.

15 Mar 2021