Hypertrophic Cardiomyopathy News and Research

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Hypertrophic cardiomyopathy is a condition that affects the heart’s ability to pump blood effectively due to the thickening (hypertrophy) of the heart muscle which becomes stiff as a result.

CDC and NIH collaborate to create Sudden Death in Young Registry

A registry of deaths in young people from conditions such as heart disease and epilepsy is being created to help researchers define the scope of the problem and set future research priorities. The National Institutes of Health and the Centers for Disease Control and Prevention are collaborating to create the Sudden Death in the Young Registry.

24 Oct 2013

Deficiency of antioxidant response protein prevents hypertrophic cardiomyopathy

University of Utah researchers have found that deficiency of an antioxidant response protein called nuclear erythroid-2 like factor-2 (Nrf2) delays or prevents hypertrophic cardiomyopathy, a type of a heart failure in which the heart muscle grows abnormally thick.

12 Oct 2013

Four new pre-clinical drug development projects at NIH develop treatment for rare disease

Four new pre-clinical drug development projects at the National Institutes of Health will target a form of blindness and diseases characterized by cardiac problems. The projects were selected for their potential to treat specific rare diseases and to help scientists uncover new information that can be shared with other researchers.

13 Sep 2013

Study: Death risk is greatest for those who developed hypertrophic cardiomyopathy in childhood

A long-term study of children with a complex heart condition called hypertrophic cardiomyopathy (HCM) found that the risk of death or need for immediate listing for heart transplantation was greatest for those who developed this disease as infants with congestive heart failure and for children who also had selective inborn errors of metabolism, a group of rare genetic disorders in which one or more of the body's key metabolic processes are disrupted.

5 Sep 2013

US scientists identify risk factors for pediatric hypertrophic cardiomyopathy

US scientists have identified key risk factors that predict which children with hypertrophic cardiomyopathy, the most common cause of sudden death in young people, are at greatest risk of death or need for heart transplant—information that could help physicians figure out who will benefit most from transplant surgery.

4 Sep 2013

University Of Virginia Gets $14.4M Grant To Fight Hypertrophic Cardiomyopathy

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28 Aug 2013

ECGs do not reduce risk of cardiovascular sudden death in young competitive athletes

The risk of cardiovascular sudden death was very small and only about 30% of the incidence were due to diseases that could be reliably detected by pre-participation screening, even with 12-lead ECGs, according to research in a U.S. high school athlete population presented March 10 at the American College of Cardiology (ACC) Scientific Sessions.

11 Mar 2013

BIDMC investigator receives $50,000 CCF grant for research on pediatric cardiomyopathy

Maria Kontaridis, PhD, an investigator in the Division of Cardiology at Beth Israel Deaconess Medical Center (BIDMC), has received a $50,000 grant from the Children's Cardiomyopathy Foundation (CCF) for her research on pediatric cardiomyopathy.

7 Mar 2013

Stanford scientists identify molecular basis for hypertrophic cardiomyopathy

When a young athlete dies unexpectedly on the basketball court or the football field, it's both shocking and tragic. Now Stanford University School of Medicine researchers have, for the first time, identified the molecular basis for a condition called hypertrophic cardiomyopathy that is the most common cause for this type of sudden cardiac death.

4 Jan 2013

USPTO approves patent for Axiogenesis’ in vitro drug discovery assay to treat HCM

The USPTO approved a patent for Axiogenesis AG for the invention of its in vitro assay to screen pharmaceutical drug candidates for effectiveness and safety in treating Hypertrophic Cardiomyopathy (HCM).

5 Dec 2012

ICD use can combat sudden death in pediatric patients with hypertrophic cardiomyopathy

A multicenter registry has demonstrated that the use of implantable cardioverter-defibrillators (ICDs) to combat sudden cardiac death in high-risk pediatric patients suffering from hypertrophic cardiomyopathy (HCM). The study is being presented Nov. 5 at the 2012 Scientific Sessions of the American Heart Association (AHA) in Los Angeles.

6 Nov 2012

Cardio exercise OK in high-risk CVD patients

US study results indicate that cardiopulmonary exercise is well tolerated, even when performed by individuals with high-risk cardiovascular disease.

1 Nov 2012

Healthcare announces important changes to the U.S. product label for Optison

GE Healthcare today announced important changes to the U.S. product label for Optison (Perflutren Protein-Type A Microspheres Injectable Suspension, USP), a contrast agent that may improve the visualization of the left ventricular border - an area of the heart that is critical to see in order to diagnose certain heart diseases such as hypertrophic cardiomyopathy.

22 Aug 2012

Study confirms link between sickle cell trait and deaths in young black competitive athletes

While some published research has hinted at the connection between the sickle cell trait and sudden cardiac death among young, athletic African-American males, which was initially observed in black military recruits 25 years ago, a new study with the first sizeable patient series definitively confirms this risk for these individuals during competitive sports.

26 Jul 2012

New U-M hESC lines now available for federally-funded research

Six new human embryonic stem cell lines derived at the University of Michigan have just been placed on the U.S. National Institutes of Health's registry, making the cells available for federally-funded research.

15 Jun 2012

Researchers discover location and effect of abnormal heart proteins

University of Guelph researchers have found the location and effect of abnormal heart proteins that can cause cardiac failure, a discovery that points to potential new ways to treat the most costly health problem in the world.

9 May 2012

Seattle Children's Hospital performs 100th heart transplant on 5-month-old baby

On Saturday, April 28, a 5-month-old baby received the 100th heart transplant performed at Seattle Children's Hospital, a significant milestone for him as well as the hospital's Heart Center and Heart Transplant Program teams.

7 May 2012

International effort to define ECG interpretation standards in athletes

On Feb. 13-14, the American Medical Society for Sports Medicine (AMSSM) partnered with the ESC Sports Cardiology Section, the PACES, other leading U.S. cardiologists, BJSM, and F-MARC in an effort to define ECG interpretation standards in athletes and develop a comprehensive online training module for physicians around the world to gain expertise in ECG interpretation and the proper evaluation of ECG abnormalities suggestive of a pathologic cardiovascular disorder.

22 Feb 2012

TomTec to launch 2D Cardiac Performance Analysis MR software

At the upcoming SCMR meeting in Orlando Florida at February 2nd -5th TomTec introduces its 2D Cardiac Performance Analysis MR software product. The tool to quantify myocardial function and deformation based on regular cardiac MRI cine imaging.

31 Jan 2012

Risk of sudden cardiac arrest while running a marathon is low in the healthy: Study

There have been reports of a marathoner collapsing suddenly with no pulse. Now a large study finds such calamities are rare and usually due to a pre-existing heart problem. The study also found such incidents are increasing as more runners try to go the distance.

12 Jan 2012