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Dilemma of single vs. double embryo transfers

Elsevier announced the publication of several commentaries in the scientific journal Reproductive BioMedicine Online on the subject of how many embryos it is safe and proper to place in a uterus, and how best to regulate this decision. It is a dilemma faced by all patients anxiously caught between no pregnancies at all or facing the prospect of twins or triplets. In this difficult place it is often all too easy to think that the latter option must be the best. But is it?

28 Jul 2011

Northeast Assisted Fertility Group extends egg donation, surrogacy program

The Northeast Assisted Fertility Group (NAFG), already among the leading surrogacy and egg donation programs in the United States, is pleased to announce its enhanced International Program, extending a more complete menu of services to citizens of England, France, Italy, Spain, Switzerland, Germany, Australia, and other countries where the practice of egg donation and surrogacy is restricted or very limited.

20 Jul 2011

Vitrolife second quarter sales increase 19% to SEK 88 million

Vitrolife: Second quarter in brief. Sales growth increased by 31 percent in local currency in the second quarter. Sales amounted to SEK 88 (73) million, corresponding to an increase by 19 percent in SEK.

14 Jul 2011

Overall risk of stillbirth low among ART children

The group looked at 60,650 singletons in a common Nordic database from ART registers in Denmark, Finland, Norway and Sweden and compared these to a control group of 360,022 naturally conceived (NC) singletons. In both groups 0.4 % of singletons were stillborn, with a definition of stillbirth as a dead child after 22 weeks of gestation.

6 Jul 2011

Fiscal problems could be mitigated by ART conceived children

In 2009, 1,547 ART children were born in public clinics in Denmark, projecting a net tax revenue of -224 million and -247 million in 25 and 50 years respectively. The authors of the study calculated that reductions of 30-50% in ART cycles following the new policy would lead to cost savings of -67 - -111 million for the Danish government in 2034.

6 Jul 2011

Cumulus cells can provide information about genetic and chromosomal status of eggs

At present, when a woman undergoes preimplantation genetic screening (PGS) in a fertility clinic, doctors are trying to select an egg or an embryo that is healthy and doesn't have a chromosome abnormality such as an extra copy of chromosome 21, which causes Down's syndrome. In order to establish this, they either have to biopsy a part of the egg called the polar body or remove a cell from the embryo for screening. Both procedures are expensive, invasive and can damage the egg or embryo.

6 Jul 2011

Frozen embryo transfer may not adversely affect neonatal outcome

In the first study, French scientists looked at neonatal outcome in terms of mode of delivery, gestational age, preterm birth rate (less than 37 weeks of gestation), mean child measurements, low birth weight (less than 2,500g) and perinatal mortality. When comparing the cryo singletons to the fresh cohort, the scientists showed that mean birth weight, mean height and head circumference were lower in the fresh population.

6 Jul 2011

EIM collects data on frozen oocyte retrieval cycles for the first time

Other important data the European IVF Monitoring group (EIM) on 2008 cycles and the International Committee Monitoring Assisted Reproductive Technologies (ICMART) on 2007 cycles highlighted were Sweden's low rate of multiple births - the lowest in the world - and Spain's 30 % share of egg donations in Europe.

6 Jul 2011

Researchers investigate predictors for adverse outcome in IVF singletons

In Sweden almost 40 000 children have now been born after IVF, around 3 500 each year, and IVF children constitute 3% of all newborns. "This represents a large number of children and any adverse outcomes related to IVF are therefore a major public health issue," said Dr. Antonina Sazonova, from Sahlgrenska University Hospital, Gothenburg, Sweden, who carried out the research with colleagues from the hospital and from Lund University.

6 Jul 2011

Cleavage stage embryo with aneuploidy can undergo genetic normalisation process

Professor William G. Kearns told the annual meeting of the European Society of Human Reproduction and Embryology that a three-day-old embryo with an incorrect number of chromosomes was capable of undergoing "a dynamic process of genetic normalisation" so that by day five, when it had developed to the blastocyst stage, it had become euploid, with the correct number of chromosomes.

5 Jul 2011

Hope for fertility spreads through postcards

The campaign sends a multiplied message of hope for fertility in form of postcards with stories, including the key message on prevention and treatment. Thousands of postcards with moving stories are expected to cross Europe until October 2011.

4 Jul 2011

Research addresses chromosomal imbalance in embryos

Joint research between the University of Kent's Professor Darren Griffin, London Bridge Fertility Centre and BlueGnome Ltd has addressed chromosomal imbalance in embryos, a condition that is currently the major cause of pregnancy loss in IVF.

4 Jul 2011

Study shows effect of maternal height on multiple implantation

The researchers say that this is the first time the effect of maternal height on multiple implantation has been shown.

4 Jul 2011

Primiparity, maternal smoking and BMI linked to risk of pre-term birth

4 Jul 2011

New model may help reduce multiple pregnancies in women

Dr Jan Holte told the annual meeting of the European Society for Human Reproduction and Embryology, that if this model were to be applied in all fertility clinics, it had the potential to reduce the twin rates to the level of just under two percent seen in the normal population. Already, another four clinics have started to use the model.

4 Jul 2011

New insight into oocyte chromosome abnormalities

Ovarian stimulation undertaken by women of advanced maternal age receiving fertility treatment may be disrupting the normal pattern of meiosis - a critical process of chromosome duplication followed by two specialised cell divisions in the production of oocytes and sperm - and leading to abnormalities of chromosome copy numbers that result in IVF failure, pregnancy loss or, more rarely, the birth of affected children with conditions such as Down's syndrome, which is caused by the inheritance of three copies of chromosome 21.

4 Jul 2011

Small 'antifreeze' molecules more effective in protecting proteins than larger ones

Scientists have made an important step forward in their understanding of cryoprotectants - compounds that act as natural 'antifreeze' to protect drugs, food and tissues stored at sub-zero temperatures.

24 Jun 2011

Antimullerian hormone test can help indicate number of eggs, pregnancy in women

Given how much patients invest in in vitro fertilization (IVF), both financially and emotionally, tools to inform couples about what they might expect during their treatment can be welcome. A study by researchers at Brown University and Women & Infants Hospital shows that as the IVF cycle is beginning, a blood test for levels of a hormone called AMH, or antimullerian hormone, can help predict the number of eggs that will be harvested.

10 Jun 2011

NHS directive to fertility clinics

NHS fertility clinics will be ordered to meet their responsibilities and provide adequate levels of IVF treatment, amid growing concerns. There are claims that a “postcode lottery” is reducing couples' chances of having a baby.

5 Jun 2011

Pacific Reproductive Center celebrates Annual Baby Reunion in Torrance

When April Gooding was born 19 years ago in Torrance, infants like her were called "test tube babies" and in vitro fertilization was still considered experimental. Nearly two decades later, almost 4 million IVF babies have been born, including several hundred who will join April and the fertility expert who helped create her as one of his first successes.

1 Jun 2011