Immune System News and Research

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Weekly cycles of once-daily anti-HIV drugs could reduce cost of HIV treatment

In a small study conducted at the U.S. National Institutes of Health (NIH), researchers have shown that it may be feasible to treat HIV-infected patients with a simple, once-daily regimen of anti-HIV drugs given in pre-planned, 7-day-on, 7-day-off cycles.

24 May 2004

Trial shows Daclizumab therapy improves multiple sclerosis outcome

A small clinical trial of patients with multiple sclerosis (MS) who did not respond to interferon alone found that adding the human antibody daclizumab improved patient outcome. Patients who received the combined therapy had a 78 percent reduction in new brain lesions and a 70 percent reduction in total lesions, along with other significant clinical improvements.

24 May 2004

Researchers have isolated a protein receptor in chickens responsible for transferring antibodies from mother to offspring

Howard Hughes Medical Institute (HHMI) researchers have isolated a protein receptor in chickens that is responsible for transferring antibodies from mother to offspring - a function critical to bestowing a temporary immunity that protects the young against infection until their own immune systems begin functioning.

24 May 2004

Clinical use of immunoassays not recommended as a primary means of assessing environmental fungal exposure

Routine clinical use of immunoassays, a type of blood test for measuring antigen-specific IgE or IgG antibodies, is not recommended as a primary means of assessing environmental fungal exposure or its harmful effects according to a report published this month in Annals of Allergy, Asthma & Immunology, the scientific journal of the American College of Allergy, Asthma and Immunology (ACAAI).

24 May 2004

Damage to the left half side of brain may make a right-handed person more susceptible to infection

A major immunological difference between the opposite halves of the human brain is now confirmed in a study published May 24, 2004 in the online edition of the Annals of Neurology. Researchers have found that damage or surgery to the left half of the brain may make a right-handed person more susceptible to being immunocompromised.

24 May 2004

Using gene therapy to fight rheumatoid arthritis

Guided by a similar principle, arthritis researchers at the University of Florida and Harvard University hope to use gene therapy to help joint cells pump out a harmless protein that parks in receptor sites, leaving a notorious inflammatory agent “circling the lot” and unable to cause pain, swelling and possible joint damage.

21 May 2004

New treatment for dry eye syndrome (keratoconjunctivitis sicca)

Researchers in the department of ophthalmology at the University of Arizona College of Medicine in Tucson played an important role in the development of Restasis, the first alternative to artificial tears for the treatment of dry eye syndrome.

21 May 2004

Zinc may help to accelerate recovery from pneumonia

The addition of zinc to standard antimicrobial treatment may accelerate recovery from pneumonia, say researchers in this week's issue of The Lancet.

20 May 2004

Cell division can be halted in multiple ways, with implications for cancer

Brown University researchers have found that there are multiple independent ways to stop cell division, a phenomenon that prevents the spread of genetic mutation, which can make cells cancerous. Results of this research, along with an accompanying editorial, were published in the current issue of the journal Molecular Cell.

20 May 2004

Network formed to tackle potentially fatal reaction to smallpox vaccine

The National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH), launched the Atopic Dermatitis and Vaccinia Network (ADVN), a nationwide research group that seeks to reduce the risk of eczema vaccinatum (EV), a severe and potentially deadly complication of smallpox immunization.

19 May 2004

Study comparing the efficacy of REMICADE® to Azathioprine alone and in combination With REMICADE®

Centocor, Inc., and Schering-Plough Corporation announced today the initiation of the SONIC (Study of Immunomodulator Naive patients in Crohn's Disease) trial that will evaluate the efficacy of REMICADE® (infliximab) versus azathioprine, a conventional immunosuppressive agent, alone and versus the combination of both drugs for the treatment of patients with Crohn's disease.

18 May 2004

Manipulation of the body’s own natural killer cells to destroy cells containing the HIV virus

Current treatments for HIV block the virus from replicating, but don’t kill the cells that contain HIV. The existence of these HIV-harboring cells -- often called the “latent” or “resting reservoir” -- is regarded by many to be the main obstacle to finding a cure for HIV.

18 May 2004

FDA today alerted consumers not to purchase or use a recalled lot of DU brand nasal decongestant spray

FDA today alerted consumers not to purchase or use a recalled lot of DU brand nasal decongestant spray (distributed by Drugs Unlimited, of Puerto Rico) because it may be contaminated with Burkholderia cepacia – a bacterium that could cause serious, potentially life-threatening infections in some patients. Individuals with compromised immune systems, especially those with cystic fibrosis, could be at risk.

17 May 2004

International plan to rid the world of dirty dozen most toxic chemicals known to humankind

The 2001 Stockholm Convention on Persistent Organic Pollutants (POPs) enters into force on Monday, May 17, marking the start of an ambitious international effort to rid the world of PCBs, dioxins and furans, and nine highly dangerous pesticides.

17 May 2004

NASA and Stanford to develop technologies for physiological monitoring of humans

NASA and Stanford University are launching an exciting new joint venture to develop technologies, instruments and systems to conduct physiological monitoring of humans in support of basic and applied space biology research.

15 May 2004

Influenza vaccine does provide protection against influenza in most asthma patients taking inhaled steroids

The influenza vaccine protected asthma patients who use inhaled steroids against type A flu, although its protection against type B flu was significantly reduced in those taking high doses of inhaled steroids, said a researcher from Baylor College of Medicine in a recent publication.

15 May 2004

Risk of artery plaques increased by use of HIV drugs

An Italian study has provided evidence that HIV drugs called protease inhibitors may increase the risk of artery "plaques."

15 May 2004

3 people with drug-resistant HIV become first to undergo a new form of gene therapy

The idea is to use a modified form of HIV to deliver an "antisense" gene to the immune cells that HIV infects. This is integrated into the cells' genome, and stays there until a cell is infected. Then it is switched on, and produces RNA complementary to the "sense" RNA encoding a viral protein. In theory, the RNAs should bind together, blocking viral replication.

14 May 2004

New Center for International Blood and Marrow Transplant Research

In their mission to improve transplant access and outcomes for patients, the National Marrow Donor Program® (NMDP) and the Medical College of Wisconsin’s International Bone Marrow Transplant Registry and Autologous Blood and Marrow Transplant Registry (IBMTR/ABMTR) have created the Center for International Blood and Marrow Transplant Research (CIBMTR.)

14 May 2004

Study of hematopoietic stem cell transplantation for severe, treatment-resistant lupus

The study will include a basic research component to examine the roles of B and T cells, white blood cells in the immune system, in triggering lupus symptoms.

14 May 2004

Immune System News and Research

Weekly cycles of once-daily anti-HIV drugs could reduce cost of HIV treatment

Trial shows Daclizumab therapy improves multiple sclerosis outcome

Researchers have isolated a protein receptor in chickens responsible for transferring antibodies from mother to offspring

Clinical use of immunoassays not recommended as a primary means of assessing environmental fungal exposure

Damage to the left half side of brain may make a right-handed person more susceptible to infection

Using gene therapy to fight rheumatoid arthritis

New treatment for dry eye syndrome (keratoconjunctivitis sicca)

Zinc may help to accelerate recovery from pneumonia

Cell division can be halted in multiple ways, with implications for cancer

Network formed to tackle potentially fatal reaction to smallpox vaccine

Study comparing the efficacy of REMICADE® to Azathioprine alone and in combination With REMICADE®

Manipulation of the body’s own natural killer cells to destroy cells containing the HIV virus

FDA today alerted consumers not to purchase or use a recalled lot of DU brand nasal decongestant spray

International plan to rid the world of dirty dozen most toxic chemicals known to humankind

NASA and Stanford to develop technologies for physiological monitoring of humans

Influenza vaccine does provide protection against influenza in most asthma patients taking inhaled steroids

Risk of artery plaques increased by use of HIV drugs

3 people with drug-resistant HIV become first to undergo a new form of gene therapy

New Center for International Blood and Marrow Transplant Research

Study of hematopoietic stem cell transplantation for severe, treatment-resistant lupus

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Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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