Induced Pluripotent Stem Cells News and Research

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Bat stem cells reveal how bats survive in a virus-filled environment

A recent Cell journal study tested the hypothesis that bats genetically induce the virus for immune evasion and provide fertile ground for replication.

15 Mar 2023

A convergent coexpression approach identifies novel genes associated with autism

The current study analyzes transcriptional convergence across many autism risk genes.

14 Mar 2023

Newly identified therapeutic target could lead to more effective treatment of glaucoma

Indiana University School of Medicine researchers have identified a new therapeutic target that could lead to more effective treatment of glaucoma.

10 Mar 2023

Johns Hopkins researchers partner with NASA to send heart “tissue-on-a-chip” specimens into space

Johns Hopkins Medicine researchers are collaborating with NASA to send human heart "tissue-on-a-chip" specimens into space as early as March.

7 Mar 2023

First induced bat iPSCs offer insights into the close relationship between bats and SARS-CoV-2 viruses

Researchers from the Icahn School of Medicine at Mount Sinai have generated the first induced pluripotent stem cells (iPSCs) from bats, gaining valuable insights into the close relationship between bats and viruses.

21 Feb 2023

Step-by-step process of rewiring cells to generate germ cell precursors

Different cell types-;say, heart, liver, blood, and sperm cells-;possess characteristics that help them carry out their unique jobs in the body.

21 Feb 2023

First fully human ovarian organoids provide insights about female reproductive health and disease

Despite the fact that we all start out as an egg cell in one of our mother's ovaries, these human reproductive organs are surprisingly under-studied.

21 Feb 2023

Pulmonary surfactant-mediated inflammatory response against SARS-CoV-2

Researchers discuss the role of a surfactant-mediated inflammatory response employed by human lungs against SARS-CoV-2.

3 Feb 2023

CuSTOM; Creating a healthier society by accelerating the translation of organoid technology

In this interview, we speak to Magdalena Kasendra at the CuSTOM Accelerator, about the organoid technology and how it has the power the revolutionize healthcare.

From Society for Laboratory Automation and Screening (SLAS) 1 Feb 2023

Schizophrenia may be linked with vascular alterations in the brain, study suggests

A study conducted in Brazil and reported in an article published in Molecular Psychiatry suggests that schizophrenia may be associated with alterations in the vascularization of certain brain regions.

19 Jan 2023

SARS-CoV-2 WA1/2020, Delta and Omicron strains found to infect human sensory neurons

Researchers evaluated the impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on the peripheral nervous system (PNS).

13 Jan 2023

Human cortical organoids implanted in mice establish functional connectivity and respond to sensory stimuli

A team of engineers and neuroscientists has demonstrated for the first time that human brain organoids implanted in mice have established functional connectivity to the animals' cortex and responded to external sensory stimuli.

29 Dec 2022

Study shows de novo origination of functional microproteins

In a new study, researchers performed a genomic analysis to investigate the origination of human microproteins of biological importance.

23 Dec 2022

Researchers identify a new pathogenic mechanism for diabetes onset in MODY3

In order to treat patients with diabetes in the best possible way it is necessary to understand the disease mechanism. MODY type 3 (MODY3) is a monogenic hereditary form of diabetes, that is caused by a genetic defect in the HNF1A gene.

22 Dec 2022

Recapitulating early stages of the human body plan in a dish

Although Michelangelo's masterpiece David captured the magnificence of the human body - how this exquisite body plan is exactly established during human development has puzzled scientists for more than a century.

21 Dec 2022

New approach enables robust intestinal mini-organs to be grown more easily in the lab

Growing human body parts in the lab is a common trope of horror movies and sci-fi books. But growing miniature organ-like tissues in the lab is already within our reach.

6 Dec 2022

Scaling up the production of customized immune cells for drug development and testing

To prevent testing on animals and create even more precise ways of testing therapeutics, the pharmaceutical industry is increasingly turning to human immune cells.

1 Dec 2022

Study suggests new strategies for making cartilage cells

As any weekend warrior understands, cartilage injuries to joints such as knees, shoulders, and hips can prove extremely painful and debilitating. In addition, conditions that cause cartilage degeneration, like arthritis and temporomandibular joint disorder (TMJ), affect 350 million people in the world and cost the US public health system more than $303 billion every year.

30 Nov 2022

The effects of mechanical forces on musculoskeletal cells and tissues

In this interview, Dr. Marina Danalache, Lab leader at the Laboratory of Cell Biology, Department of Orthopedic Surgery, University of Tübingen talks to News-Medical Life Sciences about the ongoing research on the effects of mechanical forces on musculoskeletal cells and tissues, as well as how these forces mediate homeostasis and drive pathophysiological processes.

From Bruker BioAFM 30 Nov 2022

Using human iPSC-derived cells to revolutionize the field of neurodegenerative disease

In this interview, we speak to Axol Bioscience about their human iPSC-derived cells and how they have the potential to revolutionize the field of neurodegenerative disease.

From Axol Bioscience Ltd 28 Nov 2022

Induced Pluripotent Stem Cells News and Research

Bat stem cells reveal how bats survive in a virus-filled environment

A convergent coexpression approach identifies novel genes associated with autism

Newly identified therapeutic target could lead to more effective treatment of glaucoma

Johns Hopkins researchers partner with NASA to send heart “tissue-on-a-chip” specimens into space

First induced bat iPSCs offer insights into the close relationship between bats and SARS-CoV-2 viruses

Step-by-step process of rewiring cells to generate germ cell precursors

First fully human ovarian organoids provide insights about female reproductive health and disease

Pulmonary surfactant-mediated inflammatory response against SARS-CoV-2

CuSTOM; Creating a healthier society by accelerating the translation of organoid technology

Schizophrenia may be linked with vascular alterations in the brain, study suggests

SARS-CoV-2 WA1/2020, Delta and Omicron strains found to infect human sensory neurons

Human cortical organoids implanted in mice establish functional connectivity and respond to sensory stimuli

Study shows de novo origination of functional microproteins

Researchers identify a new pathogenic mechanism for diabetes onset in MODY3

Recapitulating early stages of the human body plan in a dish

New approach enables robust intestinal mini-organs to be grown more easily in the lab

Scaling up the production of customized immune cells for drug development and testing

Study suggests new strategies for making cartilage cells

The effects of mechanical forces on musculoskeletal cells and tissues

Using human iPSC-derived cells to revolutionize the field of neurodegenerative disease

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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