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NCATS scientists identify promising compounds effective in inhibiting Zika virus replication

NCATS scientists identify promising compounds effective in inhibiting Zika virus replication

Researchers at the National Center for Advancing Translational Sciences recently identified compounds that potentially can be used to inhibit Zika virus replication and reduce its ability to kill brain cells. [More]
New research may explain why people with blood group O get more severely ill from cholera

New research may explain why people with blood group O get more severely ill from cholera

People with blood type O often get more severely ill from cholera than people of other blood types. New research from Washington University School of Medicine in St. Louis may explain why. [More]
Leading Chikungunya vaccine in clinical trial phase 2

Leading Chikungunya vaccine in clinical trial phase 2

With the first patient vaccinated, a Phase 2 clinical trial of a promising prophylactic vaccine candidate against Chikungunya fever has now commenced. The product is the most advanced Chikungunya vaccine candidate globally and is developed by the Austrian biotech company Themis Bioscience GmbH. [More]
The rise of disease ecology and its implications for parasitology

The rise of disease ecology and its implications for parasitology

The Journal of Parasitology – With a shared focus on host–pathogen relationships, parasitology and disease ecology seem to have a lot in common. But parasitology lacks the eye-catching—and wallet-opening—emphasis on known diseases. By working more closely with disease ecologists, could parasitologists gain more support for work crucial to predicting and controlling infectious diseases? [More]
Arab uprising linked to detrimental effects on health and life expectancy in several countries

Arab uprising linked to detrimental effects on health and life expectancy in several countries

The Arab uprising in 2010 and subsequent wars in the eastern Mediterranean region have had serious detrimental effects on the health and life expectancy of the people living in many of the 22 countries in the region, according to a major new analysis from the Global Burden of Disease Study 2013 (GBD 2013), published in The Lancet Global Health journal. [More]
ESCMID releases new guidelines on best practices to detect C. difficile infections

ESCMID releases new guidelines on best practices to detect C. difficile infections

The European Society of Clinical Microbiology and Infectious Diseases has just released new guidelines on best practice methods to diagnose Clostridium difficile infection (CDI). [More]
Scientists isolate new multicomponent virus from mosquitoes

Scientists isolate new multicomponent virus from mosquitoes

Scientists have identified a new "multicomponent" virus -- one containing different segments of genetic material in separate particles -- that can infect animals, according to research published today in the journal Cell Host & Microbe. [More]
Researchers develop new method to culture norovirus in intestinal cells

Researchers develop new method to culture norovirus in intestinal cells

Researchers have succeeded in culturing norovirus in human intestinal cells, a breakthrough that could help scientists develop novel therapeutics and vaccines against the debilitating effects of the virus. [More]
Cedars-Sinai study identifies metabolic enzyme that alerts the body to invading bacteria

Cedars-Sinai study identifies metabolic enzyme that alerts the body to invading bacteria

Biomedical investigators at Cedars-Sinai have identified an enzyme found in all human cells that alerts the body to invading bacteria and jump-starts the immune system. [More]
TB burden in India may be two to three times higher than current estimates, study suggests

TB burden in India may be two to three times higher than current estimates, study suggests

The number of cases of tuberculosis (TB) in India may be up to two to three times higher than current estimates, suggests a new study. [More]
High exposure to unconventional natural gas wells linked to migraine headaches, sinus and fatigue

High exposure to unconventional natural gas wells linked to migraine headaches, sinus and fatigue

New research suggests that Pennsylvania residents with the highest exposure to active natural gas wells operated by the hydraulic fracturing ("fracking") industry are nearly twice as likely to suffer from a combination of migraine headaches, chronic nasal and sinus symptoms and severe fatigue. [More]
Cloned Zika virus could be used for development of attenuated vaccine

Cloned Zika virus could be used for development of attenuated vaccine

Stopping the explosive spread of Zika virus - which can lead to birth defects in babies born to infected mothers - depends on genetic insights gleaned through new tools and models. [More]
NIH researchers discover rare, lethal inflammatory disease that affects young children

NIH researchers discover rare, lethal inflammatory disease that affects young children

National Institutes of Health researchers have discovered a rare and sometimes lethal inflammatory disease - otulipenia - that primarily affects young children. They have also identified anti-inflammatory treatments that ease some of the patients' symptoms: fever, skin rashes, diarrhea, joint pain and overall failure to grow or thrive. [More]
QUT molecular microbiologist developing new therapies to beat bacterial superbugs

QUT molecular microbiologist developing new therapies to beat bacterial superbugs

QUT molecular microbiologist Makrina Totsika is at the forefront of research to develop new therapies to beat multi-drug resistant bacteria. [More]
Sick animals disconnect from social groups leading to decrease in disease transmission, study shows

Sick animals disconnect from social groups leading to decrease in disease transmission, study shows

Sick wild house mice spend time away from their social groups, leading to a decrease in their potential for disease transmission according to a new study by evolutionary biologists from the University of Zurich in collaboration with the ETH Zurich. [More]
Geographers map internal migration across three continents to help combat infectious diseases

Geographers map internal migration across three continents to help combat infectious diseases

Geographers at the University of Southampton have completed a large scale data and mapping project to track the flow of internal human migration in low and middle income countries. [More]
NYIT researcher aims to study link between wound healing problems and methamphetamine use

NYIT researcher aims to study link between wound healing problems and methamphetamine use

A chance observation in a Southern California fast food restaurant led Luis Martinez, Ph.D., to wonder about the connections behind wound healing problems and methamphetamine use. [More]
Novel marine natural product appears to reduce pancreatic tumor size

Novel marine natural product appears to reduce pancreatic tumor size

Scientists at Florida Atlantic University's Harbor Branch Oceanographic Institute found that a deep-water marine sponge collected off of Fort Lauderdale's coast contains leiodermatolide, a natural product that has the ability to inhibit the growth of cancer cells as well as block cancer cells from dividing using extremely low concentrations of the compound. [More]
UNC bioethicist addresses roadblocks to HIV research on pregnant women

UNC bioethicist addresses roadblocks to HIV research on pregnant women

UNC School of Medicine's Anne Lyerly is addressing the urgent need for effective HIV prevention and treatment for the estimated 1.5 million women worldwide with HIV who give birth each year. [More]
Scientists find way to boost efficiency with which CRISPR-Cas9 cuts and disables genes

Scientists find way to boost efficiency with which CRISPR-Cas9 cuts and disables genes

CRISPR-Cas9 is the go-to technique for knocking out genes in human cell lines to discover what the genes do, but the efficiency with which it disables genes can vary immensely. [More]
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