Inflammasome News and Research

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New research finds microclotting and inflammatory molecule abnormalities in long-COVID

A new study published on the preprint server medRxiv* determines how endothelial activation and inflammation contribute to the formation of microclots in PASC.

18 Oct 2022

Review on Panax ginseng therapeutic efficacy for COVID-19-associated neurological diseases

In a new study, researchers discussed the therapeutic potential of Panax ginseng for COVID-19 (coronavirus disease 2019)-induced neurological diseases.

14 Oct 2022

Chinese scientists reveal a previously undefined pathway by which Mtb counteracts host immunity

Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis (TB), remains a leading infectious threat to public health worldwide.

13 Oct 2022

Study explores cell signaling dysregulation and COVID-19 severity

Researchers assessed the impact of dysregulation in cell signaling events on coronavirus disease 2019 (COVID-19) severity.

12 Oct 2022

Study finds dimethyl fumarate was not associated with an improvement in clinical outcomes in adults hospitalized with COVID-19

Researchers evaluated the efficacy of the anti-inflammatory drug dimethyl fumarate in treating COVID-19 as part of an early phase, randomized, controlled assessment trial in the UK.

28 Sep 2022

Researchers uncover a new way the immune system detects coronavirus infection

In a recent study posted to bioRxiv*, researchers in the United States demonstrated that the main protease (Mpro) of coronaviruses (CoVs) activates host inflammasome responses.

27 Sep 2022

What is the efficacy of aerosol treatment for SARS-CoV-2 infection?

In a new study, researchers assessed the efficacy of the scFv76 antibody against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) lung damage.

21 Sep 2022

Routine periodic fasting associated with lower hospitalization risk in patients with COVID-19

The main objective of a new prospective observational cohort study was to evaluate whether periodic fasting is linked with severe COVID-19 symptoms.

1 Aug 2022

Study describes biochemical pathway that leads to inflammation characteristic of autoimmune diseases

Mitochondria are self-contained organelles (they possess their own mini-chromosome and DNA) residing within cells and are charged with the job of generating the chemical energy needed to fuel functions essential to life and well-being.

13 Jul 2022

Scientists characterize type I IFN response during SARS-CoV-2 infection

In a recent study posted to the bioRxiv* preprint server, Canadian researchers assessed the impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection on interferon (IFN) response.

15 Jun 2022

A comparison of SARS-CoV-2 and influenza cytokine storms

In a recent study published in the Journal of Interferon & Cytokine Research, researchers compared the cytokine storms of pandemic influenza and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections.

9 Jun 2022

Researchers identify a gene that plays vital role in the innate human immune system

Cedars-Sinai investigators have identified a gene that plays an essential role in the innate human immune system. The gene, NLRP11, helps activate the inflammatory response that tells the body's white blood cells to go on the attack against a foreign presence.

27 May 2022

The role of pyroptosis in COVID-19

Researchers investigate the mechanisms by which SARS-CoV-2 induces NLRP3 inflammasome formation leading to pyroptosis.

25 May 2022

ANU research could lead to better treatment options for rare, deadly bacterial infection

New research from The Australian National University could lead to better treatment options for a rare but very lethal type of bacterial infection.

20 May 2022

Mitochondrial respiratory chain is essential for NLRP3 inflammasome activation

Northwestern Medicine investigators recently discovered that the mitochondrial respiratory chain — a series of protein complexes essential for a cellular respiration and energy production — is necessary for the activation of another protein complex linked to inflammation and the progression of chronic diseases, according to a study published in Nature Immunology.

12 May 2022

Inflammasome News and Research

New research finds microclotting and inflammatory molecule abnormalities in long-COVID

Review on Panax ginseng therapeutic efficacy for COVID-19-associated neurological diseases

Chinese scientists reveal a previously undefined pathway by which Mtb counteracts host immunity

Study explores cell signaling dysregulation and COVID-19 severity

Study finds dimethyl fumarate was not associated with an improvement in clinical outcomes in adults hospitalized with COVID-19

Researchers uncover a new way the immune system detects coronavirus infection

What is the efficacy of aerosol treatment for SARS-CoV-2 infection?

Routine periodic fasting associated with lower hospitalization risk in patients with COVID-19

Study describes biochemical pathway that leads to inflammation characteristic of autoimmune diseases

Scientists characterize type I IFN response during SARS-CoV-2 infection

A comparison of SARS-CoV-2 and influenza cytokine storms

Researchers identify a gene that plays vital role in the innate human immune system

The role of pyroptosis in COVID-19

ANU research could lead to better treatment options for rare, deadly bacterial infection

Mitochondrial respiratory chain is essential for NLRP3 inflammasome activation

Research describes how DNA damage can affect neural health and function

Yale researchers identify immune system culprit in severe COVID cases

Evaluating nano alum as a substitute for conventional alum-based vaccine adjuvant

Using customized 'mini-antibodies' to mitigate chronic inflammation

Yale researchers discover immune response pathway that leads to severe COVID-19

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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