Insulin Resistance News and Research

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Insulin Resistance is a condition in which the body does not respond to insulin properly. This is most common in Type II diabetes or associated with obesity, ketoacidosis, infection, and certain rare conditions. Diminished effectiveness of insulin in lowering blood glucose levels requiring 200 units or more of insulin per day to prevent hyperglycemia or ketosis.

Researchers have produced a marathon mouse that can run twice as far as normal mice

By enhancing the function of a single protein, Howard Hughes Medical Institute researchers have produced a “marathon mouse” with altered muscle composition and enough physical endurance to run twice as far as normal mice.

23 Aug 2004

Carb-conscious dieters may be lowering their risk of breast cancer

Carb-conscious dieters may be lowering their risk of breast cancer while they’re shedding pounds, based on the findings of research published in this month’s edition of the journal Cancer Epidemiology, Biomarkers & Prevention.

9 Aug 2004

Scientists create mice that don't gain weight, even when fed fat-laden, high calorie diets

By altering the expression of a single -- albeit different – gene, Drs. Roger Davis (UMASS Medical School, USA) and Ying-Hue Lee (Academia Sinica, Taiwan) have succeeded in creating two different strains of transgenic mice that don't gain weight, even when fed fat-laden, high calorie diets.

2 Aug 2004

Misfiring proteins linked to sick feeling of type 2 diabetics

After a series of studies in the laboratory of Dr. Gregory Freund, a clearer picture is emerging: A disruption of signaling proteins in the immune system may be responsible for the inflammation that makes someone with type 2 diabetes feel sick and increases the risk of serious complications.

29 Jul 2004

Influence of alcohol consumption on risk of developing hypertension and type 2 diabetes

Researchers at Wake Forest University Baptist Medical Center will seek to determine the influence of alcohol consumption on risk of developing hypertension and type 2 diabetes using data collected during a five-year study of a prediabetic condition.

29 Jul 2004

Largest diet and exercise trial in the world for people with type 2 diabetes

A massive grant of almost a million pounds has been awarded to the University of Bristol to carry out a major trial that will assess the effects of diet and exercise on people with type 2 diabetes. This trial will be the largest diet and exercise trial in the world for people with type 2 diabetes.

23 Jul 2004

Increasing levels of growth hormone may be an effective treatment for HIV lipodystrophy

Increasing the body's production of growth hormone may be an effective treatment for HIV lipodystrophy, a syndrome involving the redistribution of fat and other metabolic changes in those receiving combination drug therapy for HIV infection.

11 Jul 2004

Exercise found to be equally effective as diuretics in preventing high blood pressure and an enlarged heart

Only recently was a type of diuretic known as thiazides been found to be superior to angiotensin-converting enzyme (ACE) inhibitors and calcium antagonists (calcium channel blockers) in preventing one or more major types of cardiovascular disease.

30 Jun 2004

Geneticists have closed in on the genetic basis for risk factors of metabolic diseases

Oxford geneticists have closed in on the genetic basis for risk factors of metabolic diseases such as hypertension, obesity and diabetes.

30 Jun 2004

Novel findings on treatments for childhood obesity and early polycystic ovary syndrome (PCOS) in young girls

New research findings presented this week in New Orleans during ENDO 2004, the 86th Annual Meeting of The Endocrine Society, could help keep kids healthier.

16 Jun 2004

Asian Indian men more at risk of type 2 diabetes and cardiovascular disease

Asian Indian men are at an increased risk for type 2 diabetes and cardiovascular disease, whether overweight or not, because their bodies metabolize fat like people who are obese, according to researchers at UT Southwestern Medical Center at Dallas.

15 Jun 2004

What causes polycystic ovary syndrome?

A woman finds herself with excessive facial hair, obesity, menstrual abnormalities, infertility, and enlarged ovaries may have polycystic ovary syndrome (PCOS), an unfortunate condition thought to be caused by excessive secretion by the ovaries of androgen, a hormone associated with male characteristics.

15 Jun 2004

Higher-than-normal amounts of a selenium-containing enzyme could promote type 2 diabetes

A study by researchers at Cornell University suggests that higher-than-normal amounts of a selenium-containing enzyme could promote type 2 diabetes.

10 Jun 2004

Combination treatment may help type 2 diabetes patients

New research presented by Peter Weissman, M.D., from the University of Miami, at the 64th Annual Scientific Sessions of the American Diabetes Association shows that combination treatment with rosiglitazone maleate and metformin significantly improves certain markers of cardiovascular disease risk in patients with type 2 diabetes compared to metformin alone.

6 Jun 2004

Carbohydrates are the latest nutrient to be blamed for the rising incidence of obesity in the US

Carbohydrates are the latest nutrient to be blamed for the rising incidence of obesity in this country. Tired of playing the low-fat game only to see our belt sizes increase, Americans have looked for other macronutrients as the reason behind their growing waists.

5 Jun 2004

Polycystic ovary syndrome more common than originally thought

Researchers at Cedars-Sinai Medical Center and the University of Alabama, Birmingham, have found that a complex hormonal disorder affecting the reproductive and metabolic function of premenopausal women may be considerably more common in the United States than previously believed from earlier, smaller studies.

5 Jun 2004

Diabetes drug improves metabolic changes associated with HIV combination therapy

Use of an oral antidiabetes medication produced significant improvement in a group of patients with HIV lipodsytrophy, a syndrome involving the redistribution of fat and other metabolic changes in those receiving combination drug therapy for HIV infection.

20 May 2004

Studies identify risk factors for colon cancer in women

In new studies presented today at Digestive Disease Week in New Orleans, scientists report that women’s preferences for a female physician may delay or prevent proper colorectal screenings due to a lack of females in the field and diabetes may be a significant risk factor for development of colon cancer.

19 May 2004

Exercise reverses signs of artery disease in obese children

Healthy but obese adolescents display abnormal responses to tests of blood vessel function, but after a short course of exercise their test results match those of lean youngsters, even though they remain heavy, according to a new study in the May 19, 2004 issue of the Journal of the American College of Cardiology.