Insulin Resistance News and Research

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Insulin Resistance is a condition in which the body does not respond to insulin properly. This is most common in Type II diabetes or associated with obesity, ketoacidosis, infection, and certain rare conditions. Diminished effectiveness of insulin in lowering blood glucose levels requiring 200 units or more of insulin per day to prevent hyperglycemia or ketosis.

Myths and misconceptions about diabetes

November is designated American Diabetes Month and while raising awareness this month about preventing diabetes is important, focusing on proper treatment is just as important for those living with the disease.

15 Oct 2011

Emory researcher provides overview on 'CVD and PCOS' in APS conference

Sarah Berga, MD, former Chair of the Department of Gynecology and Obstetrics at the Emory University School of Medicine, is a researcher whose work focuses on understanding the impact of metabolic and psychological stresses on the reproductive system and as a cause of infertility, as well as on PCOS. She will provide an overview of her team's work in a presentation entitled, "CVD and PCOS." Her remarks are part of the Physiology of Cardiovascular Disease: Gender Disparities conference, October 12 at the University of Mississippi in Jackson.

15 Oct 2011

World class scientist presents fourth Environmental Microbiology Lecture

World class scientist Professor Willem M. de Vos will explain next Monday how the microbes that are closest to our hearts - gut microbes - could underpin a new way of thinking about human biology. As well as looking at our own genes, we can now include those of our microbes in studies of human health and disease. This is a significant shift in the way we approach human biology.

11 Oct 2011

Sirt1 protein enhances skeletal muscle insulin sensitivity in calorie-restricted mice

The number of individuals with type 2 diabetes is reaching epidemic proportions. One of the main risk factors for developing type 2 diabetes is resistance of cells in the body (particularly liver, fat, and skeletal muscle cells) to the effects of the hormone insulin.

11 Oct 2011

Working in shifts associated with elevated levels of stress hormone cortisol

A recent study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM) found that shift work at a young age is associated with elevated long-term cortisol levels and increased BMI. Previous studies have shown that long-term elevated cortisol levels lead to increased abdominal obesity, hypertension, diabetes and cardiovascular risk.

3 Oct 2011

Vertex announces abstracts from hepatitis C program to be presented at The Liver Meeting

Vertex Pharmaceuticals Incorporated today announced that abstracts from its hepatitis C program, including two late-breaking posters from studies of INCIVEK (telaprevir) tablets and VX-222, were accepted for presentation at The Liver Meeting, the 62nd Annual Meeting of the American Association for the Study of Liver Diseases (AASLD) in San Francisco, November 4-8, 2011.

1 Oct 2011

New targeting approach to develop an active site-directed, drug-like PTP1B inhibitor

The work of a team of scientists at Cold Spring Harbor Laboratory (CSHL) led by Professor Nicholas Tonks FRS, suggests a way to overcome one of the major technical obstacles preventing a leading therapeutic target for diabetes and obesity from being addressed successfully by novel drugs.

30 Sep 2011

Fat-rich 'western diet' fuels cardiovascular disease, type 2 diabetes and obesity

A major risk factor for cardiovascular disease, type 2 diabetes and other health- and life-threatening conditions, obesity is epidemic in the United States and other developed nations where it's fueled in large part by excessive consumption of a fat-rich "Western diet."

30 Sep 2011

Stroke risk increases with even small rises in blood pressure

Small rises of blood pressure may greatly increase a person's risk of stroke, according to new research. The study review, published in the journal Neurology, analyzed the results of 12 studies on blood pressure and stroke incidences among a total of 518,520 adults.

29 Sep 2011

Scientists reveal link between lipid cell dysfunction and metabolic diseases

By measuring the radioactive isotope carbon-14, scientists at Karolinska Institutet have revealed an association between lipid cell dysfunction and diseases such as obesity, diabetes and blood lipid disorders.

26 Sep 2011

Parental motivation could improve diabetes management in high-risk youth

A little motivation for parents could go a long way toward improving young diabetes patients' ability to manage their own care, a Wayne State University researcher believes.

26 Sep 2011

Study highlights individual and combined effect of obesity on asthma development

Belly fat, known clinically as central obesity, has been linked to the development of asthma in a new study.

26 Sep 2011

GI Dynamics introduces EndoBarrier Gastrointestinal Liner in Austria

GI Dynamics, Inc. today announced the launch of the EndoBarrier Gastrointestinal Liner in Austria, the establishment of the first two Centers of Excellence and the treatment of patients at each new Center.

21 Sep 2011

Diabetes and dementia, connection found

A new study revealed that people with diabetes may be at an increased risk of developing dementia. Scientists have suspected the link between the two diseases for several years, but several experts say this latest study highlights how treating preventable diseases like diabetes and obesity may be useful in preventing the onset of dementia.

20 Sep 2011

ONGLYZA used with insulin maintains improvement in glucose control in adults with type 2 diabetes

Bristol-Myers Squibb Company and AstraZeneca today announced results from an investigational Phase 3b clinical study in which the addition of ONGLYZA (saxagliptin) 5 mg to ongoing insulin therapy (with or without metformin) maintained reductions of blood sugar levels (glycosylated hemoglobin levels, or HbA1c) in adult patients with type 2 diabetes compared to the addition of placebo (with or without metformin) from 24 to 52 weeks.

16 Sep 2011

Linagliptin demonstrates durable reductions in blood glucose for T2D adults

Boehringer Ingelheim and Eli Lilly and Company today announced results of a 102 week Phase III study for linagliptin, which show meaningful and durable reductions in blood glucose for adults with type 2 diabetes.

16 Sep 2011

A woman's pregnancy outcome can be an indicator of future health conditions

"A woman's pregnancy outcome can be an indicator of future health conditions," stated George R. Saade, M.D., president of the Society for Maternal-Fetal Medicine and professor of obstetrics and gynecology at The University of Texas Medical Branch in Galveston, Texas.

14 Sep 2011

Pure maple syrup may promote a healthy liver

New research conducted at the University of Tokyo suggests that pure maple syrup may promote a healthy liver.

14 Sep 2011

High cholesterol and Alzheimer's disease

New research suggests that high cholesterol levels could boost the risk of Alzheimer's disease by creating more brain-clogging bits known as plaque. Researchers however didn't find any link between high cholesterol and tangles, which also clog the brain in those with Alzheimer's.

13 Sep 2011

People with high cholesterol more likely to develop Alzheimer's disease

People with high cholesterol may have a higher risk of developing Alzheimer's disease, according to a study published in the September 13, 2011, issue of Neurology, the medical journal of the American Academy of Neurology.

13 Sep 2011