Insulinoma News and Research

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COVID-19 doubles risk of early type 1 diabetes signs in high-risk children

New research in JAMA finds a temporal association between SARS-CoV-2 infections and the onset of islet autoimmunity, a precursor to type 1 diabetes, in genetically predisposed infants. The study underscores COVID-19 as a potential risk factor for the development of this form of diabetes in young children.

13 Sep 2023

Study reveals potential target for repairing beta-cell dysfunction in Type 2 diabetes

Researchers used a murine model to demonstrate that functional excision of murine PITPNA eventually led to hyperglycemia in mice.

19 Jul 2023

TEDDY study adds to a growing body of evidence that type 1 diabetes is not a single disease

New findings from the international The Environmental Determinants of Diabetes in the Young (TEDDY) study add to a growing body of evidence indicating that type 1 diabetes is not a single disease. The presentation and, perhaps, cause of autoimmune diabetes differs among genetically high-risk children, the research suggests.

22 Oct 2021

Children with multiple islet autoantibodies are more likely to progress to type 1 diabetes

Children with multiple islet autoantibodies - biological markers of autoimmunity -- are more likely to progress to symptomatic type 1 diabetes (T1D) than those who remain positive for a single autoantibody.

30 Oct 2020

C-Path receives EMA’s letter of support to facilitate the diagnoses of type 1 diabetes

The Critical Path Institute (C-Path) today announced that its Type 1 Diabetes (T1D) Consortium has received a letter of support from the European Medicines Agency (EMA) to facilitate the development and validation of the proposed regulatory qualification of pancreatic islet autoantibodies commonly used in clinical practice to diagnose T1D: insulin autoantibodies, glutamic acid decarboxylase 65, and insulinoma antigen-2 autoantibodies as enrichment biomarkers for T1D clinical trials.

29 Apr 2020

Understanding the genetic background of idiopathic ketotic hypoglycemia

Lisa is two years old. She often gets uneasy--shaking and sweating--especially in the morning. She vomits and refuses to eat. Her mother, Karoline, knows she has to act before Lisa starts to deteriorate.

9 Feb 2020

FDA approves first nasal glucagon therapy for treatment of severe hypoglycemia

The U.S. Food and Drug Administration today approved Baqsimi nasal powder, the first glucagon therapy approved for the emergency treatment of severe hypoglycemia that can be administered without an injection.

24 Jul 2019

FDA supports C-Path's Type 1 Diabetes Consortium to pursue biomarker qualification

Critical Path Institute (C-Path) announced today that its Type 1 Diabetes (T1D) Consortium has received a positive response to its Letter of Intent (LOI) from the U.S. Food and Drug Administration (FDA) detailing the FDA's decision to accept the consortium's Biomarker Initiative project into the Center for Drug Evaluation and Research (CDER) Biomarker Qualification Program (BQP).

19 Dec 2018

New research sheds light on the causes of diabetes

The main cause of all forms of diabetes is pancreatic beta-cell dysfunction. Beta cells, found in the pancreatic islets, store and release insulin.

14 Sep 2018

Nano-encapsulation of bilirubin could enhance survival rates of pancreatic islet cells

By encapsulating bilirubin within tiny nanoparticles, researchers from North Carolina State University and the Ohio State University have improved the survival rates of pancreatic islet cells in vitro in a low-oxygen environment.

18 Dec 2017

Lilly Diabetes releases Android version of Glucagon Mobile App to support diabetes caregivers

Lilly Diabetes has released an Android version of its mobile application designed for caregivers and healthcare providers who support people with diabetes. Through an injection tutorial and emergency instructions, the App can help people practice the injection steps ahead of time, which may help them feel better prepared to assist.

15 Jul 2015

Pre-POINT trial raises hope for Type 1 diabetes prevention

Giving oral insulin to children at genetic high risk of diabetes stimulates a regulatory immune response without inducing hypoglycaemia, show the findings of the Pre-POINT study.

1 May 2015

Islet autoantibody levels predict progression to diabetes

Levels of insulin autoantibodies and insulinoma-associated protein 2 autoantibodies predict the onset of diabetes in young children with islet autoimmunity, show findings from the TEDDY study.

13 Mar 2015

Many MEN1 tumour types found in children

Most tumour types reported in adult patients with multiple endocrine neoplasia Type-1 can be found in children with the condition, although rarely before the age of 10 years, shows a large study.

30 Jan 2015

Gastroenteropancreatic neuroendocrine tumors: an interview with Dr. Alexandria Phan

GEP-NETs stands for gastroenteropancreatic (GEP) neuroendocrine tumors (NETs). This is a type of rare cancer that is increasing in incidence and prevalence – more on this later.

22 Oct 2014

Six prominent surgeons receive ACS' Honorary Fellowship

Honorary Fellowship in the American College of Surgeons (ACS) was awarded to six prominent surgeons from South Africa, England, Ireland, Italy, The Netherlands, and the People's Republic of China last night during Convocation ceremonies that preceded the official opening of the College's 97th Annual Clinical Congress.

24 Oct 2011