11. November 2009 03:49
Sanofi-aventis and Regeneron Pharmaceuticals, Inc. (Nasdaq: REGN) announced today that they have entered into agreements to expand and extend their existing global collaboration to discover, develop, and commercialize fully-human therapeutic monoclonal antibodies.
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10. November 2009 07:56
Bristol-Myers Squibb Company and Alder Biopharmaceuticals, Inc., today announced a global agreement for the development and commercialization of ALD518, a novel biologic that has completed Phase IIa development for the treatment of rheumatoid arthritis.
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Posted in: Drug Trial News | Medical Condition News
Tags: Antibody, Anti-Inflammatory, Arthritis, Bone, Cancer, Education, Genetics, Immunology, Inflammatory Disease, Interleukin-6, Investment, Monoclonal Antibody, Rheumatoid Arthritis, Rheumatology
4. November 2009 03:59
Decision Resources, one of the world's leading research and advisory firms for pharmaceutical and healthcare issues, finds that 98 percent of surveyed rheumatologists indicate they will prescribe Roche's Actemra, an interleukin-6 inhibitor, for the treatment of rheumatoid arthritis following the agent's expected launch in 2010.
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29. October 2009 01:05
Pregnant women with significant symptoms of depression tend to have a stronger biological reaction to the seasonal flu vaccine than do women with lower depression levels, according to a new study.
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Posted in: Women's Health News | Disease/Infection News
Tags: Blood Pressure, Brain, CDC, Cytokines, Depression, Genetics, H1N1, Immunology, Influenza, Interleukin-6, Macrophage, Pregnancy, Psychiatry, Psychology, Smoking, Stress, Vaccine
23. October 2009 02:09
In a surprising reversal of long-standing scientific belief, researchers at the Mayo Clinic campus in Florida have discovered that inflammation in the brain is not the trigger that leads to buildup of amyloid deposits and development of Alzheimer's disease.
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19. October 2009 07:43
Genentech, Inc., a wholly-owned member of the Roche Group, today announced two-year results from a Phase III study, which showed that people with rheumatoid arthritis (RA) who received either a 4 mg/kg or 8 mg/kg dose of ACTEMRA® (tocilizumab), in combination with methotrexate, had no progression of joint damage, (75 and 83 percent, respectively, as assessed by radiograph) compared with people who received methotrexate alone (66 percent).
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Posted in: Drug Trial News | Medical Condition News
Tags: Antibody, Arthritis, Autoimmune Disease, Biotechnology, Bronchitis, Cellulitis, Cholesterol, Cytokines, Gastroenteritis, Headache, Hygiene, Hypersensitivity, Interleukin-6, Life Expectancy, Lipids, Methotrexate, Monoclonal Antibody, Osteoporosis, Pneumonia, Rheumatoid Arthritis, Rheumatology, Urinary Tract Infection
19. October 2009 06:41
A breakthrough discovery by scientists from the Mayo Clinic in Jacksonville, FL, may lead to a new treatment for Alzheimer's Disease that actually removes amyloid plaques-considered a hallmark of the disease-from patients' brains.
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6. October 2009 01:36
To help solve this long standing chicken and egg conundrum, researchers led by Jesse Stewart, Ph.D., assistant professor of psychology at Indiana University-Purdue University Indianapolis asked two critical questions. Does depression lead to elevated inflammatory proteins in the human body? Or does an increase in these proteins lead to depression? They found that the answer to the first question appears to be "yes," and the answer to the second question may be "no" among healthy adults.
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3. October 2009 00:23
Good news for procrastinating students: a nasal spray developed by a team of German scientists promises to give late night cram sessions a major boost, if a good night's sleep follows.
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18. September 2009 00:24
Fibrosis is a key feature of chronic pancreatitis and pancreatic cancer. The extensive deposition of extracellular matrix proteins fosters the development of an exocrine and endocrine organ insufficiency, and accelerates progression of the tumour. Pancreatic stellate cells (PSC) are the principal effector cells in pancreatic fibrosis. They are activated by profibrogenic mediators, which include, for example, cytokines and ethanol metabolites.
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16. September 2009 23:58
Blocking a protein that battles infection may help thwart a common cause of vision loss in chronic diseases such as diabetes, Medical College of Georgia researchers say.
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Posted in: Medical Research News | Medical Condition News
Tags: Antibody, Arthritis, Biochemistry, Blindness, Cell, Diabetes, Diabetic Retinopathy, Interleukin-6, Juvenile Diabetes, Rheumatoid Arthritis, Veterans Affairs
2. July 2009 20:21
Women who get less than the recommended eight hours sleep a night are at higher risk of heart disease and heart-related problems than men with the same sleeping patterns.
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30. June 2009 03:40
Helicobacter pylori survives in the body by manipulating important immune system cells. This is shown in a thesis from the Sahlgrenska Academy, University of Gothenburg, Sweden. The discovery may lead to new treatments against the common peptic ulcer bacterium.
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17. June 2009 18:56
Our ability to withstand stress-related, inflammatory diseases may be associated, not just with our race and sex, but with our personality as well, according to a study published in the July issue of the journal Brain, Behavior and Immunity. Especially in aging women, low levels of the personality trait extraversion may indicate that blood levels of a key inflammatory molecule have crossed over a threshold linked to a doubling of risk of death within five years.
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15. June 2009 19:08
A new approach to stimulating immune cells enhances their anticancer activity, resulting in a powerful anti-tumor response in mice, according to a study by researchers at the National Cancer Institute, a part of the National Institutes of Health. This work represents an important advance in the development of immunotherapy for cancer and appears online June 14, 2009 in Nature Medicine.
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