Interstitial Lung Disease News and Research

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Interstitial lung disease (ILD) is a broad group of lung diseases comprising of more than a hundred distinct disorders. All of these involve scarring or inflammation of the interstitial lung tissue and affect the volume of oxygen that can reach the bloodstream via the respiratory system.

Why do some people develop persistent lung sequelae after severe COVID-19?

Clinical presentation following severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) ranges from mild self-limiting illness to severe respiratory failure. Many studies have analyzed the early acute phases of coronavirus disease 2019(COVID-19), but few focused on the longer-term sequelae following infection.

2 Jan 2023

History of COVID-19 increases risk of fatigue and other long COVID symptoms in adults and children

Researchers observe that COVID-19 patients were at an increased risk of developing certain conditions.

21 Dec 2022

Comprehensive lung cell atlas offers insights into an unexpected immune niche in the airways

The most comprehensive lung cell atlas to date, from the Wellcome Sanger Institute and collaborators, has revealed 11 new lung cell types and offers detailed insight into an immune process involved in fighting lung infections.

21 Dec 2022

T-DXd leads to longer overall survival in HER2-positive metastatic breast cancer patients than T-DM1

Second-line treatment with trastuzumab deruxtecan (T-DXd) led to significantly longer overall survival compared with trastuzumab emtansine (T-DM1) in patients with HER2-positive metastatic breast cancer, according to updated results from the DESTINY-Breast03 phase III clinical trial presented at the San Antonio Breast Cancer Symposium, held December 6-10, 2022.

7 Dec 2022

T-DXd shows high efficacy in HER2-positive breast cancer patients previously treated with T-DM1

Compared with capecitabine-based regimens, trastuzumab deruxtecan (T-DXd) led to higher response rates and longer survival in the third-line setting for patients with HER2-positive metastatic breast cancer previously treated with trastuzumab emtansine (T-DM1), according to results from the phase III DESTINY-Breast02 trial presented at the San Antonio Breast Cancer Symposium, held December 6-10, 2022.

7 Dec 2022

Study reports overall response of HER2-low breast cancer patients to neoadjuvant T-DXd treatment

Patients with localized, hormone receptor-positive, HER2-low breast cancer treated with trastuzumab deruxtecan (T-DXd, Enhertu) in the neoadjuvant setting had an overall response rate of 75 percent in the absence of anastrozole and 63 percent in combination with anastrozole, according to results from the phase II TRIO-US B-12 TALENT trial presented at the San Antonio Breast Cancer Symposium, held December 6-10, 2022.

7 Dec 2022

What is the prevalence of pulmonary tissue injury among hospitalized COVID-19 patients?

Researchers identified risk factors for and the prevalence of persistent pulmonary tissue alterations among hospitalized coronavirus disease 2019 (COVID-19) patients.

7 Dec 2022

Study assesses the prevalence of residual lung abnormalities following COVID-19 hospitalization

In a new study published online in the American Thoracic Society's American Journal of Respiratory and Critical Care Medicine, researchers sought to determine the percentage of COVID-19 patients discharged from the hospital who had a type of fibrotic lung damage, known as interstitial lung disease, that requires ongoing follow-up care.

2 Dec 2022

Study links chemical composition of fine particulate air pollution to worse lung disease outcomes

People with a disease characterized by lung scarring that has no obvious cause are more likely to die if they live in areas with higher levels of air pollution composed of chemicals associated with industrial sources and vehicular traffic, according to new research led by University of Pittsburgh scientists.

17 Oct 2022

Multiple ischemic strokes and pulmonary embolism found in COVID-19 patient

In a new study, researchers described a case of a patient with acute respiratory failure and ischemic stroke.

17 Oct 2022

Researchers explore single-cell sequencing technologies to understand molecular mechanisms of autoimmune diseases

A new review discussed the applications of single-cell ribonucleic acid sequencing (scRNA-seq) in understanding autoimmune disorders.

17 Oct 2022

New screening tool accurately identifies patients at high risk of idiopathic pulmonary fibrosis

A new screening tool for electronic medical records accurately identifies patients who are at high risk of having or developing progressive scarring of the lungs, a condition called idiopathic pulmonary fibrosis, according to investigators from Weill Cornell Medicine, NewYork-Presbyterian, the University of Chicago, Brigham and Women's Hospital and Mayo Clinic.

29 Sep 2022

Anti-fibrotics found to be safe, effective for interstitial lung disease in patients with rheumatoid arthritis

For the first time, researchers have shown that a class of anti-fibrotic drugs slows the progression of interstitial lung disease (ILD) in patients with rheumatoid arthritis (RA).

22 Sep 2022

New white paper outlines the issues surrounding delays in diagnosing interstitial lung diseases

A steering committee of pulmonary experts and primary care physicians (PCPs) released today a white paper outlining the issues surrounding delays in diagnosing interstitial lung diseases (ILDs) like pulmonary fibrosis (PF).

19 Sep 2022

Study offers insight into the basic cellular pathologies driving interstitial lung disease

While most people recover from COVID-19 within a week or two, up to one-third of survivors experience persistent or new symptoms weeks and months after initial infection.

21 Jul 2022

COVID-19 outcomes improved for SARDs patients through Omicron wave

In a recent study posted to the medRxiv* pre-print server, researchers investigated coronavirus disease 2019 (COVID-19) incidence and severity among systemic autoimmune rheumatic diseases (SARDs) patients in Massachusetts, United States (US), between March 1, 2020, and January 31, 2022.

22 Jun 2022

Pulmonary and primary care experts aim to reduce the time to diagnose interstitial lung diseases

The American College of Chest Physicians (CHEST) and Three Lakes Foundation are announcing a steering committee of experts in the fields of pulmonary medicine and primary care medicine to lead an initiative called Bridging Specialties™: Timely Diagnosis for ILD Patients.

9 Jun 2022

How does COVID-19 affect patients with idiopathic pulmonary fibrosis?

A new study discusses the outcomes of idiopathic pulmonary fibrosis patients with confirmed SARS-CoV-2 infection.

6 Mar 2022

Researchers identify genetic cause of rare interstitial lung disease in a young child

New research from Washington University School of Medicine in St. Louis has solved the medical mystery of why a 2-year-old child — seemingly healthy at birth — succumbed to an undiagnosed, rare illness.

31 Jan 2022

CENTOGENE teams up with Insilico Medicine to improve therapeutic targets for Niemann-Pick disease type C

A commercial-stage company focused on generating data-driven insights to diagnose, understand and treat rare diseases, and Insilico Medicine, an end-to-end Artificial Intelligence (AI) - driven drug discovery company, today announced a research and development collaboration to accelerate the discovery of novel therapeutic targets for Niemann-Pick disease type C

21 Jan 2022

Interstitial Lung Disease News and Research

Further Reading

Why do some people develop persistent lung sequelae after severe COVID-19?

History of COVID-19 increases risk of fatigue and other long COVID symptoms in adults and children

Comprehensive lung cell atlas offers insights into an unexpected immune niche in the airways

T-DXd leads to longer overall survival in HER2-positive metastatic breast cancer patients than T-DM1

T-DXd shows high efficacy in HER2-positive breast cancer patients previously treated with T-DM1

Study reports overall response of HER2-low breast cancer patients to neoadjuvant T-DXd treatment

What is the prevalence of pulmonary tissue injury among hospitalized COVID-19 patients?

Study assesses the prevalence of residual lung abnormalities following COVID-19 hospitalization

Study links chemical composition of fine particulate air pollution to worse lung disease outcomes

Multiple ischemic strokes and pulmonary embolism found in COVID-19 patient

Researchers explore single-cell sequencing technologies to understand molecular mechanisms of autoimmune diseases

New screening tool accurately identifies patients at high risk of idiopathic pulmonary fibrosis

Anti-fibrotics found to be safe, effective for interstitial lung disease in patients with rheumatoid arthritis

New white paper outlines the issues surrounding delays in diagnosing interstitial lung diseases

Study offers insight into the basic cellular pathologies driving interstitial lung disease

COVID-19 outcomes improved for SARDs patients through Omicron wave

Pulmonary and primary care experts aim to reduce the time to diagnose interstitial lung diseases

How does COVID-19 affect patients with idiopathic pulmonary fibrosis?

Researchers identify genetic cause of rare interstitial lung disease in a young child

CENTOGENE teams up with Insilico Medicine to improve therapeutic targets for Niemann-Pick disease type C

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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