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Use of balloon-expandable stent compared with medical therapy increases stroke risk

Use of balloon-expandable stent compared with medical therapy increases stroke risk

Among patients with symptomatic intracranial arterial stenosis (narrowing of an artery inside the brain), the use of a balloon-expandable stent compared with medical therapy (clopidogrel and aspirin) resulted in an increased of stroke or transient ischemic attack (TIA), according to a study in the March 24/31 issue of JAMA. [More]
Migraine headaches with auras may increase risk of stroke

Migraine headaches with auras may increase risk of stroke

People who suffer migraine headaches with auras are at roughly double the risk of suffering the most common type of stroke. [More]
Boston Scientific announces successful implantations of WATCHMAN Device in three US patients

Boston Scientific announces successful implantations of WATCHMAN Device in three US patients

This week, three patients in the United States received the first implants of the Boston Scientific Corporation WATCHMAN™ Left Atrial Appendage Closure (LAAC) Device. [More]
A new approach to TBI therapy

A new approach to TBI therapy

Innovative angles of attack in research that focus on how the human brain protects and repairs itself will help develop treatments for one of the most common, costly, deadly and scientifically frustrating medical conditions worldwide: traumatic brain injury. [More]
Deuterium-containing sigma-1 agonist demonstrates anti-seizure, anti-inflammatory effects in TBI model

Deuterium-containing sigma-1 agonist demonstrates anti-seizure, anti-inflammatory effects in TBI model

Research results published in the Journal of Neurotrauma and conducted by the Walter Reed Army Institute of Research (WRAIR) as part of a collaboration with Concert Pharmaceuticals, Inc. showed that a novel deuterium-containing sigma-1 agonist invented at Concert, called C-10068, demonstrated anti-seizure and anti-inflammatory effects in a preclinical model of traumatic brain injury (TBI). [More]
MTfp-­siRNA reduces blood vessel infarct, improves overall brain activity in ischemic stroke model

MTfp-­siRNA reduces blood vessel infarct, improves overall brain activity in ischemic stroke model

BIOASIS TECHNOLOGIES INC., a pioneering biopharmaceutical company focused on overcoming the limitations of therapeutic drug delivery across the blood-­‐brain barrier (BBB), announces the results from an animal ischemic stroke model performed at the National Research Council Canada with the biOasis Transcend carrier peptide, MTfp and siRNA (MTfp-­‐siRNA). [More]
Combined use of enalapril and folic acid can significantly reduce risk of first stroke

Combined use of enalapril and folic acid can significantly reduce risk of first stroke

In a study that included more than 20,000 adults in China with high blood pressure but without a history of stroke or heart attack, the combined use of the hypertension medication enalapril and folic acid, compared with enalapril alone, significantly reduced the risk of first stroke, according to a study appearing in JAMA. The study is being released to coincide with its presentation at the American College of Cardiology Annual Scientific Session. [More]
Glyconanoparticles may help reduce cell damage and inflammation after stroke

Glyconanoparticles may help reduce cell damage and inflammation after stroke

Materials resulting from chemical bonding of glucosamine, a type of sugar, with fullerenes, kind of nanoparticles known as buckyballs, might help to reduce cell damage and inflammation occurring after stroke. [More]
Neuralstem reports top line data from NSI-566 Phase II trial for treatment of ALS

Neuralstem reports top line data from NSI-566 Phase II trial for treatment of ALS

Neuralstem, Inc. announced top line data from the Phase II trial of NSI-566 spinal cord-derived neural stem cells under development for the treatment of amyotrophic lateral sclerosis (ALS). The study met primary safety endpoints. The maximum tolerated dose of 16 million transplanted cells and the surgery was well tolerated. [More]
UTHealth remotely enrolls patients into acute stroke clinical trial with telemedicine method

UTHealth remotely enrolls patients into acute stroke clinical trial with telemedicine method

For the first time in the world, researchers at The University of Texas Health Science Center at Houston were able to enroll patients at other hospitals into an acute stroke clinical trial. [More]
1 in 3 people in the US could not access a stroke centre within an hour

1 in 3 people in the US could not access a stroke centre within an hour

A new study published today reports that a large proportion of the United States would be unable to access primary a stroke centre within one hour by ambulance. Stroke is a leading cause of death and disability and rapid treatment is essential to minimise damage to the brain and reduce the risk of prolonged disability. [More]
NeuroPerspective features comprehensive reviews of schizophrenia, spinal cord injury

NeuroPerspective features comprehensive reviews of schizophrenia, spinal cord injury

NI Research has released the March/April issue of NeuroPerspective, which features comprehensive reviews of two major areas: Schizophrenia and Spinal cord injury. [More]
Neuroprotective compounds can limit damage to the brain during ischemic stroke

Neuroprotective compounds can limit damage to the brain during ischemic stroke

In the 1990s, neuroscientists identified a class of drugs that showed promise in the area of stroke. NMDA receptor antagonists could limit damage to the brain in animal models of stroke. But one problem complicated testing the drugs in a clinical setting: the side effects included disorientation and hallucinations. [More]
People who exhibit resistance to aspirin may be at risk of more severe strokes

People who exhibit resistance to aspirin may be at risk of more severe strokes

People who exhibit a resistance to aspirin may be more likely to have more severe strokes than people who still respond to the drug, according to a study released today that will be presented at the American Academy of Neurology's 67th Annual Meeting in Washington, DC, April 18 to 25, 2015. [More]
Discoveries by WA research team offer further treatment hope for victims of stroke

Discoveries by WA research team offer further treatment hope for victims of stroke

A West Australian research team has made a series of discoveries which may help to minimise the damage that a stroke can cause. [More]
Simulation-based medical education teaches neurology residents how to treat stroke patients

Simulation-based medical education teaches neurology residents how to treat stroke patients

One of the most challenging cases that a first-year neurology resident physician can face is a stroke patient in the emergency department. [More]
Landmark stroke studies presented at ISC, published in NEJM suggest new treatment protocol on the horizon

Landmark stroke studies presented at ISC, published in NEJM suggest new treatment protocol on the horizon

Research presented today at the International Stroke Conference (ISC) in Nashville, Tenn. and published online in The New England Journal of Medicine (NEJM) found that the addition of the Solitaire™ Device stent thrombectomy procedure to current pharmaceutical treatment significantly reduced disability in patients suffering stroke. [More]
Clinical trial proves ‘inside the artery’ therapy improves patient outcomes after stroke

Clinical trial proves ‘inside the artery’ therapy improves patient outcomes after stroke

"This clinical trial proves beyond any doubt that inside the artery therapy is the best possible treatment for patients suffering an acute ischemic stroke from a large artery occlusion," according to Donald Frei, MD, Neuro Interventional Surgeon at Swedish Medical Center and Radiology Imaging Associates in Englewood, CO. [More]
Retigabine drug shows promise in protecting the brain against effects of ischemic stroke

Retigabine drug shows promise in protecting the brain against effects of ischemic stroke

Retigabine, a drug approved to treat epilepsy, protected the brain against the effects of ischemic stroke in a study conducted at The University of Texas Health Science Center at San Antonio. [More]
Endovascular treatment can improve patient outcomes after acute ischemic stroke

Endovascular treatment can improve patient outcomes after acute ischemic stroke

Canadian researchers have completed an international randomized controlled trial showing that a clot retrieval procedure, known as endovascular treatment (ET), can dramatically improve patient outcomes after an acute ischemic stroke. The study, led by researchers at the University of Calgary's Hotchkiss Brain Institute (HBI), shows a dramatic improvement in outcomes and a reduction in deaths from stroke. [More]
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