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Clinical study to evaluate safety of investigational cell therapy to treat chronic motor deficits after stroke

Clinical study to evaluate safety of investigational cell therapy to treat chronic motor deficits after stroke

University Hospitals Case Medical Center is the first surgical site for a Phase 2b clinical trial study to further evaluate the safety and efficacy of an investigational cell therapy for the treatment of chronic motor deficit following an ischemic stroke. [More]
Physicians failing to talk to stroke patients about end-of-life treatment preferences

Physicians failing to talk to stroke patients about end-of-life treatment preferences

US research suggests that physician-patient discussion about limitations on life-sustaining interventions following ischaemic stroke is low, poorly documented and often left too late. [More]
Aspirin resistance signals increased stroke severity

Aspirin resistance signals increased stroke severity

Stroke severity and infarct volume are significantly increased among patients who become resistant to aspirin, show study findings published in Neurology. [More]
Clinical scores unreliable in minor stroke and TIA

Clinical scores unreliable in minor stroke and TIA

Research shows that imaging findings, rather than clinical scores, are the best means of predicting recurrent events in patients with minor stroke or transient ischaemic attack. [More]
Certain gut bacteria can influence the immune system to reduce severity of stroke

Certain gut bacteria can influence the immune system to reduce severity of stroke

Certain types of bacteria in the gut can leverage the immune system to decrease the severity of stroke, according to new research from Weill Cornell Medicine. This finding can help mitigate stroke -- which is the second leading cause of death worldwide. [More]
Real-time imaging method may lead to improved stroke care

Real-time imaging method may lead to improved stroke care

According to the American Heart Association, ischemic strokes account for nearly 90 percent of all strokes. They occur when a blocked artery prevents blood from getting to the brain and usually result in long-term disability or death. Now, a team of researchers led by the University of Missouri School of Medicine has developed a new, real-time method of imaging molecular events after strokes - a finding that may lead to improved care for patients. [More]
Aralez resubmits NDA package for YOSPRALA to FDA

Aralez resubmits NDA package for YOSPRALA to FDA

Aralez Pharmaceuticals Inc., a global specialty pharmaceutical company, today announced that it has resubmitted to the U.S. Food and Drug Administration the New Drug Application ("NDA") for its investigational candidate, YOSPRALA (PA32540/PA8140) for the secondary prevention of cardiovascular disease in patients at risk for aspirin-induced gastric ulcers. [More]
Common blood test could help predict risk of second stroke

Common blood test could help predict risk of second stroke

A new discovery about ischemic stroke may allow to doctors to predict a patient's risk of having a second stroke using a commonly performed blood test and their genetic profile. [More]
RRE validated in multinational stroke cohort

RRE validated in multinational stroke cohort

The Recurrence Risk Estimator for ischaemic stroke has been validated in a prospective, multinational study. [More]
Damage to language network structural hubs can affect severity of aphasia following stroke

Damage to language network structural hubs can affect severity of aphasia following stroke

When brain regions that control speech and reading comprehension are destroyed due to blockage of blood flow, patients are often unable to speak or comprehend spoken or written language. These difficulties with language, or "aphasia," are a common symptom in the aftermath of stroke. However, in a new study published in Restorative Neurology and Neuroscience, researchers report that damage to the underlying connections among different areas of the brain can also affect the severity of aphasia. [More]
Pioglitazone drug may prevent recurrent stroke and heart attacks

Pioglitazone drug may prevent recurrent stroke and heart attacks

Pioglitazone, a drug used for type 2 diabetes, may prevent recurrent stroke and heart attacks in people with insulin resistance but without diabetes. [More]
New study to evaluate use of whole umbilical cord blood to accelerate stroke recovery

New study to evaluate use of whole umbilical cord blood to accelerate stroke recovery

A new study will evaluate the use of whole umbilical cord blood to help the brain heal quicker after an ischemic stroke. [More]
3 out of 4 young adults with stroke symptoms delay trip to hospital

3 out of 4 young adults with stroke symptoms delay trip to hospital

Up to three hours after a person experiences the first symptom of a stroke is often referred to as the "golden window." That's the period of time doctors say is crucial for patients to get to a hospital to receive medical care in order to restore blood flow to the brain and minimize or reverse damage. [More]
Oxygen sensor PHD1 identified as potential target for treatment of ischemic stroke

Oxygen sensor PHD1 identified as potential target for treatment of ischemic stroke

Scientists at VIB and KU Leuven have identified the oxygen sensor PHD1 as a potential target for the treatment of brain infarction (ischemic stroke). Despite (minor) improvements in stroke treatment, stroke remains the fourth leading cause of death and the most common reason of severe disability. [More]
FDA-approved, once-daily 24-hour aspirin now available for prevention of stroke and acute cardiac events

FDA-approved, once-daily 24-hour aspirin now available for prevention of stroke and acute cardiac events

New Haven Pharmaceuticals, Inc. today announced the availability by prescription of DURLAZA, the first and only 24-hour, extended-release aspirin capsules (162.5mg) approved by the U.S. Food and Drug Administration (FDA) for the secondary prevention of stroke and acute cardiac events, including myocardial infarction (heart attack) in high-risk cardiovascular patients. [More]
CUMC study reveals statins may help reduce heart disease risk in people with sleep apnea

CUMC study reveals statins may help reduce heart disease risk in people with sleep apnea

A new study conducted at Columbia University Medical Center has revealed some of the underlying mechanisms that may increase the risk of heart disease in people with sleep apnea. The study also found that statins -- the cholesterol-lowering medications commonly prescribed to combat heart disease -- may help reverse this process. [More]
American College of Cardiology launches new STS/ACC TAVR In-Hospital Mortality Risk App

American College of Cardiology launches new STS/ACC TAVR In-Hospital Mortality Risk App

The American College of Cardiology has launched a new STS/ACC TAVR In-Hospital Mortality Risk App and an extensively overhauled the ACC AnticoagEvaluator App, bolstering its expansive Clinical App Collection. With these new and improved apps, the ACC continues to diversify the clinical content and decision support it offers clinicians in the mobile space. [More]
ER stroke cases have some degree of preventability, UCI study shows

ER stroke cases have some degree of preventability, UCI study shows

Many strokes that required immediate treatment in emergency rooms may have been preventable, according to a University of California, Irvine study. [More]
UC San Diego's Comprehensive Stroke Center receives Gold Plus Award

UC San Diego's Comprehensive Stroke Center receives Gold Plus Award

When someone experiences a major stroke, almost two million nerve cells in the brain die each minute, emphasizing the need for rapid treatment. Stroke patients who receive life-saving interventions more quickly have a higher chance of recovery. A recent data analysis showed the Comprehensive Stroke Center at UC San Diego Medical Center exceeded national average treatment times, and as a result, has received a "Get With The Guidelines-Stroke Gold Plus Quality Achievement Award" from The American Heart Association and American Stroke Association. [More]
Treatment with antiplatelet therapy does not reduce pain crises in children with sickle cell disease

Treatment with antiplatelet therapy does not reduce pain crises in children with sickle cell disease

Treatment with the antiplatelet agent prasugrel does not significantly reduce the rate of pain crises or severe lung complications in children with sickle cell disease, according to a report published in the New England Journal of Medicine describing one of the largest and most geographically diverse international clinical trials on sickle cell disease to date. [More]
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