Joint Pain News and Research

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Bariatric surgery prior to knee replacement benefits morbidly obese patients with end-stage osteoarthritis

Previous research studies have linked obesity to adverse outcomes and increased costs following total knee replacement surgery (TKR). A new, computer model-based evaluation appearing in the Journal of Bone and Joint Surgery, supports bariatric surgery in morbidly obese patients with end-stage osteoarthritis (loss of cartilage and joint pain, caused by aging and use) prior to TKR.

22 Jan 2016

Anti-cancer drug uses 50 times less chemo to effectively destroy drug-resistant lung cancer

The cancer drug paclitaxel just got more effective. For the first time, researchers from the University of North Carolina at Chapel Hill have packaged it in containers derived from a patient's own immune system, protecting the drug from being destroyed by the body's own defenses and bringing the entire payload to the tumor.

18 Jan 2016

Novartis announces FDA approval of Cosentyx for treatment of adult patients with AS and PsA

Novartis announced today that the US Food and Drug Administration has approved Cosentyx (secukinumab) for two new indications - the treatment of adult patients with active ankylosing spondylitis (AS) and active psoriatic arthritis (PsA).

17 Jan 2016

Natural dietary supplement Arthrem significantly reduces pain and stiffness in osteoarthritis patients

New Zealand company Promisia Integrative Limited, announced today significant positive results from a clinical trial on their natural dietary supplement Arthrem. The results have been published in the December 2015 issue of Clinical Rheumatology, a prestigious international peer reviewed medical journal.

31 Dec 2015

Selexipag holds promise for treatment of pulmonary hypertension

Living with pulmonary arterial hypertension is challenging, but the chore of treating the rare heart disease may change following promising clinical trial data to be published in the Dec. 24 issue of the New England Journal of Medicine.

24 Dec 2015

Lupuzor may become first non-immunosuppressant therapy for lupus

Lupuzor may become the first specific and non-immunosuppressant therapy for lupus, a disabling autoimmune disease that is currently incurable.

15 Dec 2015

Scientists find effective antiviral mechanisms to inhibit chikungunya virus

Scientists looking at the antiviral mechanisms of two previously identified human monoclonal antibodies have found they potently inhibit chikungunya virus (CHIKV) at multiple stages of infection.

11 Dec 2015

Plasmacytoid dendritic cells may not contribute to late-stage lupus

For years, biomedical researchers have suspected that a specific set of immune cells are responsible for causing disease in lupus patients, but until now they haven't known for sure one way or the other.

8 Dec 2015

Alleviating big toe joint pain in patients

Prefabricated foot orthoses and rocker-sole footwear (in which the sole of the shoe is curved) are effective at reducing peak pressure under the big toe in people with a condition called first metatarsophalangeal joint osteoarthritis, but new research shows that they achieve this through different mechanisms.

8 Dec 2015

Preventable comorbidities common in cerebral palsy patients

Medical comorbidities are common in patients with cerebral palsy and may impact on their mobility, report researchers.

2 Dec 2015

Chikungunya may cause severe brain infection

The mosquito-borne virus chikungunya may lead to severe brain infection and even death in infants and people over 65, according to a new study that reviewed a chikungunya outbreak on Reunion Island off the coast of Madagascar in 2005-2006.

26 Nov 2015

Opdivo (nivolumab) approved to treat patients with advanced renal cell carcinoma

The U.S. Food and Drug Administration today approved Opdivo (nivolumab) to treat patients with advanced (metastatic) renal cell carcinoma, a form of kidney cancer, who have received a certain type of prior therapy.

23 Nov 2015

Resistance strength training reduces pain, increases function in people with hand OA

Resistance strength training reduces pain and increases function and treatment satisfaction in people with hand osteoarthritis, according to new research findings presented this week at the American College of Rheumatology Annual Meeting in San Francisco.

6 Nov 2015

Patients experience improvements in joint specific pain and function after weight-loss surgery

After weight-loss surgery, 57 percent of patients with significant mobility issues before surgery no longer had them and about 70 percent of those with severe knee and hip pain or disability, experienced improvements in joint specific pain and function, according to new study, funded by the National Institutes of Health, that followed patients for three years.

5 Nov 2015

Rheumatoid arthritis significantly increases risk of death due to cardiovascular causes

Rheumatoid arthritis (RA) has been associated with increased risk of death in the past, but a new study by investigators from Brigham and Women's Hospital brings that risk into sharper focus. Using data from the Nurses' Health Study, which has followed more than 100,000 female registered nurses since 1976, researchers found that rheumatoid arthritis significantly increased participants' overall risk of death, especially risk of death due to respiratory or cardiovascular causes.

3 Nov 2015

UTMB scientists work with InBios International to develop novel diagnostic test for chikungunya

A novel and affordable diagnostic test for chikungunya will soon be available thanks to the work of researchers at the University of Texas Medical Branch at Galveston in partnership with a commercial lab.

30 Oct 2015

Minimally invasive implant procedure effective for patients with sacroiliac joint dysfunction

A minimally invasive implant procedure is highly effective in reducing pain and disability for patients with sacroiliac joint (SIJ) dysfunction, reports a clinical trial in the November issue of Neurosurgery, official journal of the Congress of Neurological Surgeons, published by Wolters Kluwer.

23 Oct 2015