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Junk DNA could accelerate development of gene therapies

21. September 2009 11:36
Scientists have identified how a protein enables sections of so-called junk DNA to be cut and pasted within genetic code - a finding which could speed development of gene therapies. [More]

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Oxidative DNA damage: Primary cause of mutation

8. September 2009 00:10
A study that tracked genetic mutations through the human equivalent of about 5,000 years has demonstrated for the first time that oxidative DNA damage is a primary cause of the process of mutation - the fuel for evolution but also a leading cause of aging, cancer and other diseases. [More]

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Research on Ewing's sarcoma could lead to drugs for patients who do not respond to chemotherapy

2. September 2009 04:47
Researchers at Huntsman Cancer Institute (HCI) at the University of Utah have shed new light on Ewing's sarcoma, an often deadly bone cancer that typically afflicts children and young adults. Their research shows that patients with poor outcomes have tumors with high levels of a protein known as GSTM4, which may suppress the effects of chemotherapy. [More]

Posted in: Child Health News | Medical Condition News

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Research reveals the reason why some patients with Ewing's sarcoma do not respond to chemotherapy

31. August 2009 06:48
Researchers at Huntsman Cancer Institute (HCI) at the University of Utah have shed new light on Ewing's sarcoma, an often deadly bone cancer that typically afflicts children and young adults. Their research shows that patients with poor outcomes have tumors with high levels of a protein known as GSTM4, which may suppress the effects of chemotherapy. The research is published online today in the journal Oncogene. [More]

Posted in: Child Health News | Medical Research News

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Research study highlights the biological importance of Vitamin D in humans and other primates

19. August 2009 07:16
A new study has concluded that one key part of the immune system, the ability of vitamin D to regulate anti-bactericidal proteins, is so important that is has been conserved through almost 60 million years of evolution and is shared only by primates, including humans - but no other known animal species. [More]

Junk DNA may not be so ‘junky’ after all

20. May 2009 15:28
Scientists have called it "junk DNA." They have long been perplexed by these extensive strands of genetic material that dominate the genome but seem to lack specific functions. Why would nature force the genome to carry so much excess baggage? [More]

Posted in: Medical Research News

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A new approach for detecting functional genomic regions

12. March 2009 15:25
A team that includes researchers from the National Institutes of Health (NIH) has found a new way of detecting functional regions in the human genome. The novel approach involves looking at the three-dimensional shape of the genome's DNA and not just reading the sequence of the four-letter alphabet of its DNA bases. [More]

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Breakthrough in understanding the phenomenon of nucleolar dominance

5. December 2008 08:54
Since the machinery involved in nucleolar dominance is some of the same machinery that can go haywire in diseases such as cancer, Pikaard and his collaborators' research may have important implications for applied medical research. [More]

Scientists uncover new RNA processing mechanism and a new class of small RNAs

26. November 2008 22:47
A very small fraction of our genetic material - about 2% - performs the crucial task scientists once thought was the sole purpose of the genome: to serve as a blueprint for the production of proteins, the molecules that make cells work and sustain life. [More]

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New gene-silencing pathway found in plants

17. November 2008 22:30
Biologists at Washington University in St. Louis have made major headway in explaining a mechanism by which plant cells silence potentially harmful genes. [More]

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Scientists show how "junk" DNA may be a major driver for evolution

5. November 2008 07:16
In a paper published in Genome Research on Nov. 4, scientists at the Genome Institute of Singapore (GIS) report that what was previously believed to be "junk" DNA is one of the important ingredients distinguishing humans from other species. [More]

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Evolving complexity out of junk DNA

12. February 2008 12:47
The study, published in Proceedings of the National Academy of Sciences, USA, claims to have solved this scientific riddle by analysing the genomics of primitive living fishes such as sharks and lampreys and their spineless relatives, such as the sea squirts. [More]

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Beginnings of complex life traced to microRNA

12. February 2008 12:39
Dartmouth College researchers and colleagues from the University of Bristol in the U.K. have traced the beginnings of complex life, i.e. vertebrates, to microRNA. [More]

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RNA-associated introns guide nerve-cell channel production

7. February 2008 20:50
Researchers at the University of Pennsylvania School of Medicine have discovered that introns, or junk DNA to some, associated with RNA are an important molecular guide to making nerve-cell electrical channels. [More]

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New explanation for how regulatory networks of genes evolved

15. November 2007 00:39
When ancient retroviruses slipped bits of their DNA into the primate genome millions of years ago, they successfully preserved their own genetic legacy. [More]

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