Kaposi's Sarcoma News and Research

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Kaposi's sarcoma is a cancer that develops from the cell lining the lymph or blood vessels. The cancer appears as red, purple, or brown raised tumors or spots over the skin.

Scientists discover new mechanism for viral replication

Researchers at the University of Pennsylvania School of Medicine have identified a new strategy that Kaposi's Sarcoma Associated Herpesvirus (KSHV) uses to dupe infected cells into replicating its viral genome.

17 Aug 2007

Delta-9-tetrahydrocannabinol opens door for virus that causes Kaposi's sarcoma

The major active component of marijuana could enhance the ability of the virus that causes Kaposi's sarcoma to infect cells and multiply, according to a team of researchers at Harvard Medical School.

2 Aug 2007

Kaposi sarcoma tumors arise independently from multiple cells

Kaposi sarcoma is unique among cancers because most tumors grow from a small number of different cells, whereas nearly all other cancers arise from a single cell, according to a study published online July 10 in the Journal of the National Cancer Institute.

11 Jul 2007

Cancer risk in HIV, transplant patients

HIV/AIDS and kidney transplant patients are at much greater risk of contracting 20 different types of cancer than the general population, according to a land mark paper in The Lancet.

8 Jul 2007

FDA approves VELCADE plus DOXIL combination for multiple myeloma

Ortho Biotech Products has announced the U.S. Food and Drug Administration (FDA) has approved the use of DOXIL (doxorubicin HCl liposome injection) in combination with VELCADE (bortezomib) for Injection to treat patients with multiple myeloma who have not previously received VELCADE and have received at least one prior therapy.

23 May 2007

Herpes infection may be symbiotic

Mice with chronic herpes virus infections can better resist the bacterium that causes plague and a bacterium that causes one kind of food poisoning, researchers report in Nature.

17 May 2007

Researchers identify human genes targeted by a virus believed to cause Kaposi's sarcoma

University of Florida researchers have identified specific human genes targeted by a virus believed to cause Kaposi's sarcoma, a rare form of cancer associated with AIDS and with organ transplants that causes patches of red or purple tissue to grow under people's skin.

11 May 2007

New chemical agent, MCP110, provides synergistic effect to standard drugs

Integrating the use of drugs targeted to specific cancer proteins into current chemotherapy regimens to improve the efficacy of systemic treatment is an important clinical goal at Fox Chase Cancer Center.

16 Apr 2007

Scientists discover new approach for treating virus-induced lymphomas

Kaposi's sarcoma herpesvirus (KSHV) is a human tumor virus and an etiological agent for Kaposi's sarcoma and primary effusion lymphoma (PEL). PELs are aggressive lymphomas with reported median survival time shorter than six months after diagnosis.

19 Mar 2007

Kaposi's sarcoma-associated herpesvirus tricks cells to become tumors

Researchers at the University of Pennsylvania School of Medicine have discovered how the Kaposi's sarcoma-associated herpesvirus (KSHV) subverts a normal cell process in order to promote tumor growth.

8 Nov 2006

Enzyme discovery could reduce Kaposi sarcoma tumour growth and lead to drugs suitable for treating other viral cancers

A report in the Journal of Biological Chemistry shows that inhibition of heme oxygenase-1, an enzyme involved in iron metabolism, reduces Kaposi sarcoma tumor growth. This discovery could result in the production of new drugs to treat this and other viral cancers.

28 Apr 2006

Researchers identify critical human cell surface molecule involved in infection by Kaposi's sarcoma herpesvirus

Researchers at the National Institute of Allergy and Infectious Disease (NIAID) have identified a critical human cell surface molecule involved in infection by Kaposi's sarcoma herpesvirus (KSHV), the virus that causes Kaposi's sarcoma and certain forms of lymphoma.

11 Apr 2006

Photodynamic therapy may be an effective treatment for infections of the oral cavity

Researchers found that the bacteria S. mutans, as well as fungal organisms of the genus Candida, cultured from HIV patients, were highly susceptible to killing with minimal doses of PDT, both in laboratory dishes and on biofilms grown on denture material.

13 Mar 2006

Protein thought to promote lymphoma by merely preventing cancer cells from dying appears to actively promote cancer cell growth

A protein previously thought to merely hinder the activity of a key cellular protein linked to cancer cell death, now appears to mimic the cellular signaling of that protein; potentially leading to the development of lymphoma.

22 Aug 2005

Antiretroviral therapy may prevent excess risk of some cancers in people with HIV

In people infected with human immunodeficiency virus (HIV), highly active anti-retroviral therapy (HAART) may prevent most excess cases of Kaposi sarcoma and non-Hodgkin lymphoma, according to a new study in the March 16 issue of the Journal of the National Cancer Institute.

18 May 2005

Poor survival rates in some cancers related to lack of clinical trial participation

In a new study Archie Bleyer, M.D. of the M. D. Anderson Cancer Centre in Houston and colleagues have discovered that mortality and poor survival rates among young adults and older adolescents with some cancers may be explained in part by the lack of participation in clinical trials.

28 Mar 2005

Antiretroviral therapy may prevent some cancers in people with HIV

In people infected with human immunodeficiency virus (HIV), highly active antiretroviral therapy (HAART) may prevent most excess cases of Kaposi sarcoma and non-Hodgkin lymphoma, according to a new study in the March 16 issue of the Journal of the National Cancer Institute.

15 Mar 2005

Thalidomide - new treatment for cancer

Thalidomide, famous in the 60's because of limb deformities in babies born to women who had taken it for morning sickness, was withdrawn in 1961. Now doctors say it could be used as a treatment for cancer.

8 Mar 2005

Liquorice - the black stuff we love to eat, may help prevent cancer

Liquorice - the black stuff we love to eat, contains a compound - glycyrrhizic acid which may stop people with a herpes virus from developing cancer.A research team at New York University found the compound - glycyrrhizic acid - possibly has the ability to stop the virus triggering a form of cancer called Kaposi sarcoma.

2 Mar 2005

Important and previously unrecognized trigger for breast cancer

A small sequence of DNA in the envelope (Env) protein of a mouse breast tumor virus (called MMTV) can transform breast cells into cancer cells, according to a study by Katz et al. in the February 7 issue of The Journal of Experimental Medicine.

31 Jan 2005