Kidney News and Research

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Calcipotriol drug offers a potential treatment option for fibrotic diseases

Liver fibrosis results from an excessive accumulation of tough, fibrous scar tissue and occurs in most types of chronic liver diseases. In industrialized countries, the main causes of liver injury leading to fibrosis include chronic hepatitis virus infection, excess alcohol consumption and, increasingly, nonalcoholic steatohepatitis (NASH).

26 Apr 2013

Stem cell transplant regimen to treat neuroblastoma in children appears to be more toxic in US

The stem cell transplant regimen that was commonly used in the United States to treat advanced neuroblastoma in children appears to be more toxic than the equally effective regimen employed in Europe and Egypt, according to a new study to be presented at the 26th annual meeting of the American Society of Pediatric Hematology Oncology in Miami April 24-27.

25 Apr 2013

Combinations of sEH inhibition and PPARγ activation have beneficial effects on cardiometabolic syndrome

Scientists at the Medical College of Wisconsin and the University of California at Davis, led by Dr. John Imig and Dr. Bruce Hammock have determined the synergistic actions of inhibiting soluble epoxide hydrolase (sEH) with tAUCB (trans-4-(4-[3-adamantan-1-yl-ureid]-cyclohexyloxy)-benzoic acid) and activating peroxisome proliferator-activator receptorγ (PPARγ) with the thiazolidinedione rosiglitazone on the pathological progression of cardiometabolic syndrome.

25 Apr 2013

Study: Regional anesthesia associated with with fewer postoperative complications in orthopedic surgery patients

A study published in the May issue of Anesthesiology discovered that spinal or epidural anesthesia, types of regional anesthesia that numb patients from the abdomen to the toes, were associated with fewer postoperative complications and death than general anesthesia in patients undergoing primary hip or knee replacement.

25 Apr 2013

Experts say there is more need for organ donation in Hispanic community

April is National Donate Life Month, held to encourage organ and tissue donation and to celebrate donors who give a new life to others. Organ donors are always in short supply. In the United States, more than 118,000 people are waiting for organ transplants, and 19 percent are Hispanic.

25 Apr 2013

U.S. files suit against Novartis in alleged kickback scheme

The suit accuses the drugmaker of giving pharmacies discounts and rebates to promote the use of the drug Myfortic.

25 Apr 2013

First Edition: April 24, 2013

Today's headlines include stories about the health law's implementation as well as health policy developments from Capitol Hill.

24 Apr 2013

Nanogels to attack lupus: an interview with Dr Look and Dr Fahmy, Yale University

Nanogels are synthetic particles that can be used for drug delivery. They are approximately 100 nm to 200 nm in diameter, and are made from safe, biocompatible materials: a gel-like interior and a lipid exterior.

24 Apr 2013

Therapy originally conceived for cancer could hold promise for weight loss, say researchers

Researchers have long known that cancerous tumors grow collections of abnormal blood cells, the fuel that feeds this disease and keeps it growing. Now, new evidence in an animal model suggests that blood vessels in the fat tissue of obese individuals could provide the same purpose-and could provide the key to a new way for people to lose weight.

24 Apr 2013

Consuming grapes may protect against organ damage associated with metabolic syndrome

Consuming grapes may help protect against organ damage associated with the progression of metabolic syndrome, according to research presented Monday at the Experimental Biology conference in Boston. Natural components found in grapes, known as polyphenols, are thought to be responsible for these beneficial effects.

23 Apr 2013

Clinical Research Forum selects sickle cell project among 'Top 10' clinical research achievements of 2012

Pioneering research led by Johns Hopkins scientists on the use of partially matched bone marrow transplants to wipe out sickle cell disease has been selected as one of the Top 10 Clinical Research Achievements of 2012 by the Clinical Research Forum.

22 Apr 2013

Janssen Diabetes Forum: A medical education initiative for management of type 2 diabetes

Launched today in Beerse, the Janssen Diabetes Forum (www.janssendiabetesforum.com) is a novel medical education initiative, which has been developed to contribute to the understanding of the latest developments in the management of type 2 diabetes.

22 Apr 2013

Study identifies potential drug targets that interfere with cancer metabolism

A massive study analyzing gene expression data from 22 tumor types has identified multiple metabolic expression changes associated with cancer.

22 Apr 2013

Monoclonal antibody inhibits tumor growth in angiosarcoma and breast cancer

A monoclonal antibody targeting a protein known as SFPR2 has been shown by researchers at the University of North Carolina to inhibit tumor growth in pre-clinical models of breast cancer and angiosarcoma.

20 Apr 2013

Taking painkillers before race leads to unrecognised problems

Many competitors try to prevent pain interfering with their performance by taking painkillers that are readily available in pharmacies and supermarkets, say the authors.

20 Apr 2013

Drug that targets phosphate does not improve CVD measures in patients with mild kidney disease

High phosphate levels in the blood carry increased heart-related risks, but taking a drug that targets phosphate does not improve cardiovascular measures in patients with mild kidney disease, according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology (JASN).

19 Apr 2013

Study: Mediterranean diet associated with lower risk of hyperuricemia in older adults

According to a study published in the Journals of Gerontology Series A: Biological Sciences and Medical Sciences, a baseline adherence to a Mediterranean diet (MeDiet) is associated with a lower risk of hyperuricemia, defined as a serum uric acid (SUA) concentration higher than 7mg/dl in men and higher than 6mg/dl in women.

19 Apr 2013

Study shows chemical shift MRI can help differentiate clear cell renal carcinoma from other renal cancer

Adding "chemical shift" techniques to MRI can help differentiate clear cell renal cell carcinoma from other types of renal cell cancer, a new study shows. That differentiation can help physicians better determine treatment for these patients.

19 Apr 2013

New health MOT-style programme likely to uncover more diabetes, kidney or heart patients

University of Leicester researchers have found that the NHS Health Check Programme is likely to find 440,000 people each year who have diabetes or chronic kidney disease or who are at high risk of cardiovascular disease or diabetes.

19 Apr 2013

Study examines effect of slow walking speed in kidney disease patients

Kidney disease patients who have slower walking speed on physical performance tests seem to be more burdened by their disease than patients who perform well on lower extremity physical performance tests, according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology.

19 Apr 2013

Kidney News and Research

Calcipotriol drug offers a potential treatment option for fibrotic diseases

Stem cell transplant regimen to treat neuroblastoma in children appears to be more toxic in US

Combinations of sEH inhibition and PPARγ activation have beneficial effects on cardiometabolic syndrome

Study: Regional anesthesia associated with with fewer postoperative complications in orthopedic surgery patients

Experts say there is more need for organ donation in Hispanic community

U.S. files suit against Novartis in alleged kickback scheme

First Edition: April 24, 2013

Nanogels to attack lupus: an interview with Dr Look and Dr Fahmy, Yale University

Therapy originally conceived for cancer could hold promise for weight loss, say researchers

Consuming grapes may protect against organ damage associated with metabolic syndrome

Clinical Research Forum selects sickle cell project among 'Top 10' clinical research achievements of 2012

Janssen Diabetes Forum: A medical education initiative for management of type 2 diabetes

Study identifies potential drug targets that interfere with cancer metabolism

Monoclonal antibody inhibits tumor growth in angiosarcoma and breast cancer

Taking painkillers before race leads to unrecognised problems

Drug that targets phosphate does not improve CVD measures in patients with mild kidney disease

Study: Mediterranean diet associated with lower risk of hyperuricemia in older adults

Study shows chemical shift MRI can help differentiate clear cell renal carcinoma from other renal cancer

New health MOT-style programme likely to uncover more diabetes, kidney or heart patients

Study examines effect of slow walking speed in kidney disease patients

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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