Kidney Disease News and Research

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Amgen announces decision to stop ganitumab Phase 3 trial in advanced pancreatic cancer

Amgen today announced a decision to stop the ganitumab (AMG 479) Phase 3 GAMMA (Gemcitabine and AMG 479 in Metastatic Adenocarcinoma of the Pancreas) trial following the recommendation of an independent Data Monitoring Committee (DMC) overseeing the trial.

9 Aug 2012

Frailty may explain early dialysis initiation and mortality link

A high prevalence of frailty among patients starting dialysis may help to explain why early dialysis initiation in chronic kidney disease is associated with a reported increase in mortality, say US researchers.

7 Aug 2012

Less is definitely more for men who undergo nephrectomy

Researchers have identified a link between complete kidney removal and erectile dysfunction, a manifestation of endothelial dysfunction that often precedes cardiovascular disease.

6 Aug 2012

Potential new drug to treat common inherited kidney disease

Scientists at UC Santa Barbara have demonstrated in the laboratory that a new drug is effective in treating a very common kidney disease -- although it will be a few years before it becomes available for clinical testing. The findings resulted from a collaboration between UCSB and a biotech firm based in Indiana. The study is published in this week's Journal of the American Society of Nephrology.

3 Aug 2012

Research roundup: Massachusetts health reform; Role of race and insurance in kidney transplantation

Access to Care After Massachusetts' Health Care Reform: A Safety Net Hospital Patient Survey -- Policy analysts have long said that Massachusetts and its 2006 health reform law provide great insight into the federal health law and how its expansion of insurance coverage will play out.

3 Aug 2012

Weill Cornell Medical College receives NCATS grant to fund Clinical and Translational Science Center

Weill Cornell Medical College has received $49.6 million from the National Center for Advancing Translational Sciences (NCATS), of the National Institutes of Health (NIH), to fund its Clinical and Translational Science Center (CTSC).

3 Aug 2012

People with diabetes, hypertension and hyperlipidemia have difficultly managing all 3 conditions

Most people who have diabetes, high blood pressure, and high cholesterol have difficultly managing all three conditions; indeed, success is fleeting for those who do manage all three, according to a Kaiser Permanente Institute for Health Research study that appears online in the American Heart Association journal Circulation: Cardiovascular Quality and Outcomes.

1 Aug 2012

Around 1.4 million of Americans with celiac disease are unaware of it

Roughly 1.8 million Americans have celiac disease, but around 1.4 million of them are unaware that they have it, a Mayo Clinic-led analysis of the condition's prevalence has found.

1 Aug 2012

Obesity and heart disease risk in children: an interview with Joana Kist-van Holthe

'What defines obesity in children' is a very important question, primarily because we need to use one definition in order to be able to compare the prevalence of obesity in different countries. It is also important to have a single definition in order to evaluate whether interventions are successful or not.

31 Jul 2012

Health systems must prepare for aging population living with HIV

"Many health systems are not ready to cope with the relatively new phenomenon" of people living with HIV (PLHIV) growing older, PlusNews reports. "Data on aging with HIV is largely restricted to the developed world and very little is known about older Africans living with virus, despite the high caseload in this region," the news service writes, adding, "A July 2012 supplement of the medical journal, AIDS, notes that an estimated three million people in sub-Saharan Africa aged 50 and older are HIV-positive -- 14 percent of all infected adults.

30 Jul 2012

Rituximab also benefits patients with kidney disorder

A drug commonly used to treat immune disorders such as lymphoma and arthritis also benefits patients with an immune disorder of the kidneys that can lead to kidney failure, according to a study appearing in an upcoming issue of new study in the Journal of the American Society of Nephrology (JASN).

28 Jul 2012

Study finds disparities in the assessment of patients for kidney transplant

Young black patients and patients without private health insurance are less likely to be assessed for a kidney transplant when they start dialysis, according to a study appearing in an upcoming issue of the Clinical Journal of the American Society of Nephrology (CJASN).

26 Jul 2012

Low serum albumin increases graft failure risk in kidney-transplant children

Children with hypoalbuminemia undergoing kidney transplantation are at an increased risk for graft failure, US research shows.

24 Jul 2012

Scientists identify mechanisms by which GLP-1 protects against kidney disease, diabetes

Scientists at Joslin Diabetes Center have identified biological mechanisms by which glucagon-like peptide-1 (GLP-1), a gut hormone, protects against kidney disease, and also mechanisms that inhibit its actions in diabetes.

24 Jul 2012

New investment to fund Chiasma's Octreolin Phase 3 pivotal program for acromegaly

Chiasma, Inc., a privately held biopharma company, announced that it closed a $38.5 million equity financing co-led by new investor Abingworth and current investor MPM Capital that also included investments from existing shareholders 7 Med Health Ventures, ARCH Venture Partners, F3 Ventures and Fredric Price, Chiasma's Chairman & CEO.

23 Jul 2012

As AIDS conference opens, health panel urges treatment of all HIV infections

An international health panel has recommended for the first time that all HIV patients be treated with antiretroviral drugs, even when the virus's impact on their immune system is shown to be small. The nonprofit International Antiviral Society-USA cited new evidence that untreated infection with the human immunodeficiency virus that causes AIDS can also lead to a range of other conditions, including cardiovascular disease and kidney disease.

23 Jul 2012

Phosphate binders may cause unexpected harm to blood vessels in patients with CKD

Drugs commonly prescribed to patients with chronic kidney disease (CKD) may not be as strongly effective as once thought, and may cause unexpected harm to blood vessels, according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology (JASN).

20 Jul 2012

Low serum albumin associated with higher risk of graft failure in pediatric kidney transplants

For children receiving kidney transplants, a potentially correctable blood condition present in about one in four recipients is associated with a moderately increased risk of the graft's later failure, suggesting that clinicians should weigh whether transplant is advisable when the condition is present, according to UC Davis research presented today at the 24th International Congress of the Transplantation Society in Berlin.

20 Jul 2012

Sanquin, Baxter enter manufacturing services agreement for plasma therapies

Baxter International Inc. today announced that it has entered into a manufacturing services agreement with Stichting Sanquin Bloedvoorziening (Sanquin Blood Supply Foundation) in the Netherlands that will provide Baxter up to 1.6 million liters of incremental plasma fractionation capacity annually to support global growth of plasma-derived treatments.

From Baxter International Inc. 20 Jul 2012

Positive preliminary results from Feraheme phase III study on iron deficiency anemia

AMAG Pharmaceuticals, Inc. today reported preliminary results from the second phase III study from its global registrational program for Feraheme (ferumoxytol) in patients with iron deficiency anemia (IDA) regardless of the underlying cause.

19 Jul 2012

Kidney Disease News and Research

Amgen announces decision to stop ganitumab Phase 3 trial in advanced pancreatic cancer

Frailty may explain early dialysis initiation and mortality link

Less is definitely more for men who undergo nephrectomy

Potential new drug to treat common inherited kidney disease

Research roundup: Massachusetts health reform; Role of race and insurance in kidney transplantation

Weill Cornell Medical College receives NCATS grant to fund Clinical and Translational Science Center

People with diabetes, hypertension and hyperlipidemia have difficultly managing all 3 conditions

Around 1.4 million of Americans with celiac disease are unaware of it

Obesity and heart disease risk in children: an interview with Joana Kist-van Holthe

Health systems must prepare for aging population living with HIV

Rituximab also benefits patients with kidney disorder

Study finds disparities in the assessment of patients for kidney transplant

Low serum albumin increases graft failure risk in kidney-transplant children

Scientists identify mechanisms by which GLP-1 protects against kidney disease, diabetes

New investment to fund Chiasma's Octreolin Phase 3 pivotal program for acromegaly

As AIDS conference opens, health panel urges treatment of all HIV infections

Phosphate binders may cause unexpected harm to blood vessels in patients with CKD

Low serum albumin associated with higher risk of graft failure in pediatric kidney transplants

Sanquin, Baxter enter manufacturing services agreement for plasma therapies

Positive preliminary results from Feraheme phase III study on iron deficiency anemia

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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