Kidney Failure News and Research

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Frailty test for elderly also helps measure transplant candidates

A simple, 10-minute bedside assessment conducted prior to surgery appears to be the best method yet for predicting which kidney transplant patients will do well with their new organs, new Johns Hopkins research suggests.

21 Feb 2012

Patient education program may help reduce kidney transplant-related disparities

Being educated about your health and your treatment options is a good thing. According to a new study, kidney failure patients who take part in an education program are more likely to get evaluated for a kidney transplant.

17 Feb 2012

Lab-based treatment reminders may not be effective for CKD patients

Laboratory-based treatment reminders meant to improve physicians' prescribing habits for patients with chronic kidney disease (CKD) may not be effective, according to a study appearing in an upcoming issue of the Clinical Journal of the American Society Nephrology.

17 Feb 2012

Whole-genome sequencing helps trace the path of European E. coli outbreak

Using whole-genome sequencing, a team led by researchers from Harvard School of Public Health (HSPH) and the Broad Institute has traced the path of the E. coli outbreak that sickened thousands and killed over 50 people in Germany in summer 2011 and also caused a smaller outbreak in France.

7 Feb 2012

Study examines link between blood pressure and risk of ESRD under 'real world' conditions

An upward revision of the blood pressure numbers used to identify risk of end-stage renal disease (ESRD) might actually help doctors provide better care for their patients, said the authors of a study in patients with chronic kidney disease.

3 Feb 2012

Home-based dialysis treatments appear to decline in developed countries

Home-based dialysis treatments are on the rise in both the developing and developed worlds, but developed countries appear to be turning to them less often, according to a study appearing in an upcoming issue of the Journal of the American Society Nephrology.

3 Feb 2012

Majority of children can safely quit anti-rejection drugs after liver transplant from parents

Physicians at three transplant centers have found in a pilot study that a majority of children who receive liver tissue from a parent can eventually stop using immunosuppression (anti-rejection) medications safely. These drugs, which tamp down natural immune function, have been linked to a bevy of complications, including cancer, diabetes, hypertension and kidney failure.

1 Feb 2012

KineMed, Pfizer enter research collaboration on metabolic diseases

KineMed, Inc. today announced a non-exclusive research collaboration with Pfizer Inc. for the advancement of novel approaches towards metabolic disease, in particular Type II Diabetes.

30 Jan 2012

Upper GI bleeding causes serious health problems in patients with kidney failure

Bleeding in the upper gastrointestinal (GI) tract causes serious health problems—and even early deaths—for many patients with kidney failure, according to a study appearing in an upcoming issue of the Journal of the American Society Nephrology.

20 Jan 2012

New biomarkers can predict risk of kidney failure in patients with diabetes

Scientists at Joslin Diabetes Center have identified two novel markers that, when elevated in the blood stream, can predict accurately the risk of renal (kidney) failure in patients with Type 1 and Type 2 diabetes.

20 Jan 2012

TNF receptors 1 and 2 may predict kidney disease in diabetes

Levels of certain blood proteins indicate which diabetes patients will likely develop life-threatening kidney problems in the future, according to two studies appearing in an upcoming issue of the Journal of the American Society Nephrology.

20 Jan 2012

Study examines effect of MELD score-based allocation on post-liver transplant kidney failure

Research from the University of Michigan Health System shows the risk for kidney failure among liver transplant recipients is higher following the implementation of Model of End Stage Liver Disease (MELD), a policy change in 2002 that altered how liver transplant allocation is decided.

18 Jan 2012

Voraxaze receives FDA approval for treatment of toxic methotrexate levels

The U.S. Food and Drug Administration today approved Voraxaze (glucarpidase) to treat patients with toxic levels of methotrexate in their blood due to kidney failure.

18 Jan 2012

Nurse donates kidney to patient

A nurse offered to donate her own kidney to a 23-year-old patient. Allison Batson spent two years on the transplant floor of Emory University Hospital before her encounter with Clay Taber, a recent Auburn University graduate who fell sick one day after his 22nd birthday. He was diagnosed with kidney failure. The Auburn University graduate was diagnosed with Goodpasture's syndrome, a rare autoimmune disease that can result in severe damage to the kidneys and lungs.

17 Jan 2012

Safety nets in Australia’s Medicare questioned while expert claims $3 billion inappropriate use

In a scathing article for the Medical Journal of Australia published on Monday, GP Dr Tony Webber has described the Medicare scheme as a “monster”. He wrote, “I estimate that $2 billion to $3 billion are spent inappropriately each year.” As former chief of the Professional Services Review - set up to police Medicare - he said he gained insight into how dysfunctional the system had become.

16 Jan 2012

Smart injectable nanotherapeutics could improve treatment for Type I diabetes

A research collaboration between the Wyss Institute for Biologically Inspired Engineering at Harvard University and Children's Hospital Boston has developed "smart" injectable nanotherapeutics that can be programmed to selectively deliver drugs to the cells of the pancreas. Although this nanotechnology will need significant additional testing and development before being ready for clinical use, it could potentially improve treatment for Type I diabetes by increasing therapeutic efficacy and reducing side effects.

13 Jan 2012

Researchers publish first detailed figures that show risk of Rasilez and ACE inhibitors or ARBs

Researchers at St. Michael's Hospital have published the first detailed figures showing the risk of using the prescription drug Rasilez in combination with certain other blood pressure-lowering medications.

13 Jan 2012

Findings on cell working could lead to test and therapy for kidney failure caused by E. coli

New findings by St. Michael's researchers about the way cells work could lead to a test and therapy for kidney failure caused by E. coli

11 Jan 2012

UCSF, Sanofi enter $3.1 million collaboration to identify diabetes drug targets

The University of California, San Francisco has signed an alliance with international pharmaceutical company Sanofi to share expertise in diabetes research and identify drug targets that could lead to new therapies for both type 1 and type 2 diabetes.

11 Jan 2012

MAL3-101 appears to have potent anti-tumor effects on multiple myeloma

A new study from SUNY Downstate Medical Center in Brooklyn, New York, shows that MAL3-101, a recently developed inhibitor of the heat shock protein 70 (Hsp70), appears to have potent anti-tumor effects on multiple myeloma, a bone marrow cancer.

10 Jan 2012