Kidney Transplant News and Research

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A kidney transplant is an operation where a healthy kidney from one person (the donor) is transferred to a person who has little or no kidney function (the recipient).

Living Donor Paired Exchange becomes first Canada-wide organ donation registry

Yesterday, the Living Donor Paired Exchange performed the first match run to include kidney patients and donors from all across Canada. In doing so, it became the first Canada-wide organ donation registry.

1 Dec 2010

Baylor Health Care System receives $20 million to benefit transplantation initiatives

Baylor Health Care System Foundation announces that Annette C. and Harold C. Simmons have pledged $20 million to benefit transplantation initiatives within Baylor Health Care System. In recognition of this transformational gift, Baylor will rename the institute the Annette C. and Harold C. Simmons Transplant Institute.

29 Nov 2010

Jefferson Hospital offers shortest wait times for patients seeking kidney transplant: SRTR

A recent listing of Philadelphia adult kidney transplant programs by The Scientific Registry of Transplant Recipients (SRTR) has listed the transplant program at Thomas Jefferson University Hospital as having the shortest wait times for patients seeking a transplant among programs that have a three-year survival rate of greater than 90 percent.

29 Nov 2010

Interim results from H.P. Acthar Gel study in patients with advanced diabetic nephropathy

On November 20 at the American Society of Nephrology 43rd Annual Meeting, interim results presented from an ongoing, randomized prospective study conducted independently by James A. Tumlin, MD, at the University of Tennessee College of Medicine Chattanooga indicated that 9 of 15 patients (60%) with advanced diabetic nephropathy who are currently enrolled in the study and have completed or are still undergoing a six month course of treatment with H.P. Acthar ® Gel have exhibited a clinically significant decrease in proteinuria and achieved stabilized renal function.

22 Nov 2010

Acthar Gel may be a viable treatment option for resistant nephrotic syndrome

On November 20 at the American Society of Nephrology 43rd Annual Meeting, Columbia University Assistant Professor of Clinical Medicine Andrew Bomback, MD, presented results from a patient case series assessing the potential therapeutic value of H.P. Acthar Gel (repository corticotropin injection) as a treatment for patients with nephrotic syndrome, a kidney disorder characterized by excessive loss of urinary protein.

22 Nov 2010

VYTORIN reduces major vascular events in patients with chronic kidney disease

In a new investigational study of VYTORIN, the cholesterol-lowering medicine from Merck, VYTORIN 10/20 mg reduced the incidence of first major vascular events defined as non-fatal heart attacks or cardiac death, stroke or any revascularization procedure by a highly statistically significant 16.1 percent compared to placebo, Study of Heart and Renal Protection study involved more than 9,000 patients who, on average, had advanced or end-stage chronic kidney disease (CKD)

22 Nov 2010

Racial and socioeconomic disparities exist in kidney transplantation

Research shows that people with low incomes are more likely to develop kidney failure and less likely to receive a living donor kidney transplant than people of other socioeconomic classes.

22 Nov 2010

Alexion's Soliris Phase 2 clinical study for aHUS meets primary, secondary endpoints

Alexion Pharmaceuticals, Inc. announced today that a Phase 2 clinical study investigating Soliris (eculizumab) as a treatment for patients with atypical Hemolytic Uremic Syndrome (aHUS) who are resistant to plasma therapy met primary and key secondary endpoints with high levels of statistical and clinical significance, according to results presented today at the American Society of Nephrology (ASN) annual meeting in Denver.

21 Nov 2010

Research suggests new therapeutic approach to prevent transplant rejection

UCLA researchers have pinpointed the culprit behind chronic rejection of heart, lung and kidney transplants. Published in the Nov. 23 edition of Science Signaling, their findings suggest new therapeutic approaches for preventing transplant rejection and sabotaging cancer growth.

19 Nov 2010

University of Missouri researchers find key to combating medication non-adherence

Medications do not have a chance to fight health problems if they are taken improperly or not taken at all. Non-adherence to medications costs thousands of lives and billions of dollars each year in the United States alone, according to the New England Healthcare Institute. Now, researchers at the University of Missouri have developed an intervention strategy that is three times more effective than previously studied techniques at improving adherence in patients.

18 Nov 2010

National pilot program facilitates kidney paired-donation transplants

A computer algorithm developed at Carnegie Mellon University matched living kidney donors with medically compatible transplant candidates late last month as the national Organ Procurement and Transplantation Network (OPTN), operated by the United Network for Organ Sharing (UNOS), began a national pilot program to increase the number of kidney paired-donation (KPD) transplants.

17 Nov 2010

HealthGrades evaluates nation's top-performing hospitals in organ transplantation

HealthGrades, the nation's leading independent ratings organization, today made available to organ transplant patients a list of those hospitals with the best track record for survival and chances of receiving a donor organ. HealthGrades annual evaluation of the nation's top-performing hospitals in organ transplantation includes clinical quality data, based on patient outcomes, for each of the 210 adult acute care hospitals that perform transplants.

17 Nov 2010

NephRx initiates NX001 Phase I clinical trial to prevent DGF in kidney transplant patients

NephRx Corporation today announced that it has initiated a Phase I clinical trial of its lead compound NX001 and has successfully dosed the first subject in the study. NX001, a kidney growth factor peptide that has demonstrated good safety and promising efficacy in two animal models of acute renal failure, is in development for the prevention of delayed graft function (DGF) in kidney transplantation patients.

11 Nov 2010

Conference of The MacLean Center for Clinical Medical Ethics to focus on health disparities

The 22nd annual conference of The MacLean Center for Clinical Medical Ethics at the University of Chicago will be held at the University of Chicago Law School, 1111 E. 60th Street, on Fri., Nov. 12, from 1 to 5 pm, and Sat., Nov. 13, from 7:30 am to 5:15 pm.

10 Nov 2010

Kidney disease registry could help clinicians to evaluate treatment strategies for CKD patients

A registry of health care information on patients with mild to moderate chronic kidney disease (CKD) could help physicians improve care for affected individuals, according to a study appearing in an upcoming issue of the Clinical Journal of the American Society Nephrology (CJASN). The results suggest that officials could use such a registry to develop a national surveillance system to identify and track various aspects of CKD.

4 Nov 2010

FDA approves cancer drug Afinitor for treatment of rare genetic disorder

The U.S. Food and Drug Administration approved the cancer drug Afinitor (everolimus) on Friday to treat patients with subependymal giant cell astrocytoma (SEGA) associated with tuberous sclerosis (TS), a rare genetic disorder. This approval was for treatments of SEGA that can not be treated with surgery.

1 Nov 2010

UK HealthCare transplant recipient wins at 2010 U.S. Transplant Games

One transplant recipient from UK HealthCare, Dan Gutenson of Stanford, Ky., joined the 36 other members of "Team Kentucky" in Madison, Wisconsin for the 2010 U.S. Transplant Games this past summer. Gutenson, who received his kidney transplant in Sept. 2009, suffered from polycystic disease and received a kidney from a living donor in the church he pastors in Lincoln County, Ky.

30 Oct 2010

Access to kidney transplantation increases for elderly patients

Elderly patients with kidney failure get kidney transplants more often than they did a decade ago, according to a study appearing in an upcoming issue of the Clinical Journal of the American Society of Nephrology (CJASN). The results suggest that the chances of receiving a kidney transplant are better than ever for an older patient who needs one.

29 Oct 2010

Systemic amyloidosis patient to receive triple organ transplant

In 2005, then 40-year-old Walt McGuire was playing hockey twice a week, working full-time and chasing his young daughter. Then one day, he noticed after one trip up the stairs to catch her, he couldn't catch his breath. A few days later his legs were swollen. After numerous trips to different doctors, McGuire finally was diagnosed with a rare blood disorder called amyloidosis.

28 Oct 2010

Tengion presents data on Neo-Kidney Augment at Transplantation's Annual Scientific Exchange

Tengion, Inc. a leader in regenerative medicine, presented new data on Saturday, October 23, 2010 in a podium presentation at the American Society for Transplantation's Annual Scientific Exchange in Orlando, FL. The presentation highlighted new early data from Tengion's Neo-Kidney Augment development program demonstrating promising improvements in kidney function with an autologous cellular therapy approach to kidney regeneration in a canine model of chronic kidney disease.

26 Oct 2010

Kidney Transplant News and Research

Further Reading

Living Donor Paired Exchange becomes first Canada-wide organ donation registry

Baylor Health Care System receives $20 million to benefit transplantation initiatives

Jefferson Hospital offers shortest wait times for patients seeking kidney transplant: SRTR

Interim results from H.P. Acthar Gel study in patients with advanced diabetic nephropathy

Acthar Gel may be a viable treatment option for resistant nephrotic syndrome

VYTORIN reduces major vascular events in patients with chronic kidney disease

Racial and socioeconomic disparities exist in kidney transplantation

Alexion's Soliris Phase 2 clinical study for aHUS meets primary, secondary endpoints

Research suggests new therapeutic approach to prevent transplant rejection

University of Missouri researchers find key to combating medication non-adherence

National pilot program facilitates kidney paired-donation transplants

HealthGrades evaluates nation's top-performing hospitals in organ transplantation

NephRx initiates NX001 Phase I clinical trial to prevent DGF in kidney transplant patients

Conference of The MacLean Center for Clinical Medical Ethics to focus on health disparities

Kidney disease registry could help clinicians to evaluate treatment strategies for CKD patients

FDA approves cancer drug Afinitor for treatment of rare genetic disorder

UK HealthCare transplant recipient wins at 2010 U.S. Transplant Games

Access to kidney transplantation increases for elderly patients

Systemic amyloidosis patient to receive triple organ transplant

Tengion presents data on Neo-Kidney Augment at Transplantation's Annual Scientific Exchange

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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