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Characterizing the brain, cell by cell

Characterizing the brain, cell by cell

My group develops approaches to study cell-to-cell signaling in the brain – how the cells of the brain talk to each other. The brain is heterogeneous, probably more so than any other organ in our body, and many of its functions depend on the unique characteristics of these cells. [More]
Researchers uncover mechanism of resistance used by triple negative breast cancer

Researchers uncover mechanism of resistance used by triple negative breast cancer

Breast cancer cells are evasive, finding ways to bypass drugs designed to stop their unchecked growth. [More]
UC San Diego researchers receive CIRM grants to advance studies on Zika virus and cancer

UC San Diego researchers receive CIRM grants to advance studies on Zika virus and cancer

The Independent Citizens Oversight Committee of the California Institute for Regenerative Medicine has approved a pair of $2 million awards to University of California San Diego School of Medicine researchers to advance studies of new treatments for Zika virus infections and the use of stem cell-derived natural killer (NK) cells to target ovarian cancer and other malignancies. [More]
Blinking prompts eye muscles to realign vision, new study finds

Blinking prompts eye muscles to realign vision, new study finds

Every few seconds, our eyelids automatically shutter and our eyeballs roll back in their sockets. [More]
Researchers develop new high-tech medical device to make brain surgery safer

Researchers develop new high-tech medical device to make brain surgery safer

A new high-tech medical device to make brain surgery safer has been developed by researchers at the University of Adelaide. [More]
Chemotherapy prior to surgery could improve prognosis in African-American breast cancer patients

Chemotherapy prior to surgery could improve prognosis in African-American breast cancer patients

Administering chemotherapy to African-American breast cancer patients prior to surgery could improve their prognosis and survival rates from the disease, according to a new study. [More]
Precision medicine advances diagnosis and treatment of children with brain tumors

Precision medicine advances diagnosis and treatment of children with brain tumors

Precision medicine - in which diagnosis and treatments are keyed to the genetic susceptibilities of individual cancers - has advanced to the point where it can now impact the care of a majority of children with brain tumors, a new study by investigators at Dana-Farber/Boston Children's Cancer and Blood Disorders Center suggests. [More]
NYU Langone scientists discover mechanism behind many disease-related genetic deletions

NYU Langone scientists discover mechanism behind many disease-related genetic deletions

Scientists at NYU Langone Medical Center have discovered the mechanisms behind a genetic change known to cause a set of related diseases. [More]
Salk scientists show how microenvironment signals encourage growth of pancreatic tumors

Salk scientists show how microenvironment signals encourage growth of pancreatic tumors

Just as an invasive weed might need nutrient-rich soil and water to grow, many cancers rely on the right surroundings in the body to thrive. [More]
Researchers generate structural models for protein families with metagenomic sequences

Researchers generate structural models for protein families with metagenomic sequences

For proteins, appearance matters. These important molecules largely form a cell's structures and carry out its functions: proteins control growth and influence mobility, serve as catalysts, and transport or store other molecules. [More]
TSRI scientists develop new method to enhance drug discovery and protein research

TSRI scientists develop new method to enhance drug discovery and protein research

A team led by scientists at The Scripps Research Institute (TSRI) has developed a versatile new method that should enhance the discovery of new drugs and the study of proteins. [More]
Mayo Clinic researchers identify genetic promoter that drives lung cancer formation

Mayo Clinic researchers identify genetic promoter that drives lung cancer formation

Researchers at Mayo Clinic have identified a genetic promoter of cancer that drives a major form of lung cancer. [More]
Exposure to insecticides that mimic melatonin could put people at higher risk for diabetes

Exposure to insecticides that mimic melatonin could put people at higher risk for diabetes

Synthetic chemicals commonly found in insecticides and garden products bind to the receptors that govern our biological clocks, University at Buffalo researchers have found. [More]
CeMM scientists develop new method by integrating CRISPR genome editing with single-cell sequencing

CeMM scientists develop new method by integrating CRISPR genome editing with single-cell sequencing

Genome editing using CRISPR/Cas9 "gene scissors" is a powerful tool for biological discovery and for identifying novel drug targets. [More]
Influenza experts examine evolution of avian disease

Influenza experts examine evolution of avian disease

Few influenza viruses are as widespread and adaptable as avian influenza viruses, and scientists are not entirely sure why. [More]
Scientists identify 'molecular barcode' in blood samples that can predict survival of Ebola patients

Scientists identify 'molecular barcode' in blood samples that can predict survival of Ebola patients

Scientists have identified a 'molecular barcode' in the blood of patients with Ebola virus disease that can predict whether they are likely to survive or die from the viral infection. [More]
Eosera introduces new solution for earwax impaction

Eosera introduces new solution for earwax impaction

EOSERA™, Inc. , a Dallas-based biotechnology innovator founded by two veterans of the pharmaceutical industry, today announced the introduction of Earwax MD—the ideal solution for those who dread the time, worry, and expense of a doctor’s visit to clear their ears of burdensome earwax impaction. [More]
New way of repurposing existing drugs could unearth promising treatments for Parkinson’s disease

New way of repurposing existing drugs could unearth promising treatments for Parkinson’s disease

By bringing together cutting-edge stem cell technologies and computational biology, researchers at Oxford University have developed a unique way to identify existing drugs that could potentially be repurposed for treating Parkinson’s. [More]
Researchers uncover structure of cancer cell receptor protein that paves way for drug development

Researchers uncover structure of cancer cell receptor protein that paves way for drug development

A team of researchers from Case Western Reserve University School of Medicine has helped uncover the elusive structure of a cancer cell receptor protein that can be leveraged to fight disease progression. [More]
Study identifies molecular signals that maintain nerve cell structures in the adult brain

Study identifies molecular signals that maintain nerve cell structures in the adult brain

Humans and other vertebrates depend on a portion of the brain called the hippocampus for learning, memory and their sense of location. Nerve cell structures in the adult hippocampus are sustained by factors whose identities have remained largely mysterious so far. [More]
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