Large Intestine News and Research

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Soy protein diet increases susceptibility to Clostridioides difficile infection

According to a recent study published in the journal Cell Reports, a diet rich in soy protein increases human Clostridioides difficile susceptibility by increasing the gut amino acids (AAs) levels and promoting the growth of Lactobacillus.

18 Sep 2022

New method for organoid production could help advance research studies

As the idea of growing tiny human organs in lab dishes has moved in recent years from futuristic science fiction to actual bioscientific reality, the usefulness of organoids as a research tool for studying the digestive system swiftly encountered a bottleneck-;these valuable tissues are quite difficult to make.

28 Jul 2022

Are Mexican free-tailed bats a SARS-CoV-2 reservoir?

In a new study, investigators analyzed whether Mexican free-tailed bats were a SARS-CoV-2 reservoir.

21 Jul 2022

Researchers discover new stem cell mechanism in the gut

Your gut is a wondrous place. A special layer of cells that coats the insides of your small and large intestines takes in nutrients and water from what you ate while keeping anything bad out of your system.

13 Jul 2022

Study identifies a protein that plays key role in protecting the gastrointestinal tract from inflammation

A protein called Zbtb46, expressed by specialized immune cells, has a major role in protecting the gastrointestinal tract from excessive inflammation, according to a study from researchers at Weill Cornell Medicine.

13 Jul 2022

New computer model can accurately predict the communities formed by human gut microbes

The communities formed by human gut microbes can now be predicted more accurately with a new computer model developed in a collaboration between biologists and engineers, led by the University of Michigan and the University of Wisconsin.

7 Jul 2022

Researchers explore how diet and feeding patterns affect intestinal microbes

An estimated 500 to 1,000 bacterial species reside in each person's gut, perhaps numbering 100,000 trillion microorganisms.

5 Jul 2022

Prebiotic fiber inulin offers a protective effect against the damage of high-salt diet

New research in rats finds a diet high in the prebiotic fiber inulin offered a protective effect against the damage of a high-salt diet.

27 Jun 2022

Using a harmless amoeba to protect children from dangerous infections

Innovative efforts at the University of Virginia School of Medicine to use a harmless amoeba to protect children from dangerous infections has won critical financial support from The Hartwell Foundation.

10 Jun 2022

Use of computer-aided technology during colonoscopy increases adenoma detection rate

Colonoscopies performed with computer-aided detection, or artificial intelligence, (AI) saw an increase in the overall rate of detection of adenoma, or cancerous and precancerous polyps, by 27 percent in average-risk patients, according to new data presented today at the Digestive Disease Week Annual Meeting.

24 May 2022

Tabula sapiens, most comprehensive human cell atlas

In a recent study published in the journal Science, researchers created an atlas termed the Tabula sapiens for over 400 distinct cell types of humans. Several aspects of human physiology were revealed by the atlas, such as how different types of cells splice genes differently.

16 May 2022

Long COVID is characterized SARS-CoV-2 antigen persistence in the gut mucosa

A new study published in the journal Gastroenterology used upper and lower gastrointestinal endoscopy to assess whether gut antigen persistence leads to post-acute COVID-19 in patients with or without post-acute COVID-19 symptoms.

3 May 2022

Study investigates intestinal ischemia in COVID-19 patients

A team of Italian scientists has presented case reports of five coronavirus disease 2019 (COVID-19) patients undergoing emergency surgery for intestinal ischemia.

28 Apr 2022

Miss rate of precancerous polyps in colorectal cancer screening reduced by artificial intelligence

Artificial intelligence reduced by twofold the rate at which precancerous polyps were missed in colorectal cancer screening, reported a team of international researchers led by Mayo Clinic.

18 Apr 2022

Potential new diagnostic marker for ulcerative colitis discovered

An international research collaboration has discovered a potential new diagnostic marker for ulcerative colitis in a trans-ethnic analysis of Japanese and white patients.

10 Feb 2022

ACP guidelines: Uncomplicated diverticulitis can be treated in an outpatient setting without antibiotics

According to two new clinical guidelines from the American College of Physicians, uncomplicated diverticulitis can be treated in an outpatient setting without antibiotics.

18 Jan 2022

Research may lead to new treatment options for Crohn's disease patients

Results of a new study by researchers at Case Western Reserve University represent a step toward improving our understanding of Crohn's disease and the factors that cause its intestinal inflammation.

10 Jan 2022

Eating human food profoundly impacts the microbiome of black bears

A recent study suggests that eating human food has a pronounced effect on the microbiome of black bears.

3 Jan 2022

AI tool can reduce the need for invasive diagnostic procedures in ulcerative colitis

When visiting a doctor, many patients prefer non-invasive procedures over invasive and potentially painful ones.

13 Dec 2021

Lef1 gene restricts formation of cancer stem cell niches to suppress colorectal tumor growth

The new research findings help to understand mechanisms that lead to different types of intestinal tumors. They show that the Lef1 gene suppresses the development and growth of colorectal cancer by restricting the formation of cancer stem cell niches.

18 Nov 2021