Leukemia News and Research RSS Feed - Leukemia News and Research

Leukemia (Leukaemia) is a cancer of the blood cells. It is the most common type of blood cancer and affects 10 times as many adults as children. Most people diagnosed with leukemia are over 50 years old. No one knows why some people develop leukemia and others do not. However, scientists have identified some risk factors for the disease. Most people who have known risk factors do not get leukemia, while many who do get the disease have none of these risk factors. During the early stages of leukemia, there may be no symptoms. Many of the symptoms of leukemia don't become apparent until a large number of normal blood cells are crowded out by leukemia cells.
Personalized cancer vaccine improves outcomes for patients with AML, clinical study shows

Personalized cancer vaccine improves outcomes for patients with AML, clinical study shows

A personalized cancer vaccine markedly improved outcomes for patients suffering from acute myeloid leukemia (AML), a potentially lethal blood cancer, in a clinical trial led by investigators at Beth Israel Deaconess Medical Center. [More]
Stem cell-based risk scoring tool could predict AML patient’s response to standard treatment

Stem cell-based risk scoring tool could predict AML patient’s response to standard treatment

Leukemia researchers at Princess Margaret Cancer Centre have developed a 17-gene signature derived from leukemia stem cells that can predict at diagnosis if patients with acute myeloid leukemia (AML) will respond to standard treatment. [More]
New research reveals role of two genetic mutations in subset of acute myeloid leukemia

New research reveals role of two genetic mutations in subset of acute myeloid leukemia

Two genetic mutations known to play a role in many solid cancers might also help explain why a subset of acute myeloid leukemia (AML) patients develop the disease, according to new research from The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute. [More]
Research findings point to inherited genetic basis of ALL risk in children

Research findings point to inherited genetic basis of ALL risk in children

A late-breaking abstract being presented today during the 58th American Society of Hematology Annual Meeting and Exposition in San Diego identifies inherited genetic mutations in the gene IKZF1 that confer a higher likelihood of developing pediatric acute lymphocytic leukemia (ALL). [More]
Experimental T-cell therapy shows promise in preventing AML relapse

Experimental T-cell therapy shows promise in preventing AML relapse

Fred Hutchinson Cancer Research Center announced promising results from an early trial in which patients with high-risk acute myeloid leukemia received genetically engineered immune cells. [More]
Scientists discover ribosomal protein-based cancer signature

Scientists discover ribosomal protein-based cancer signature

A research team at the University of Basel's Biozentrum has investigated the expression of ribosomal proteins in a wide range of human tissues including tumors and discovered a cancer type specific signature. [More]
Scientists identify potential dual-acting therapeutic strategy for aggressive form of breast cancer

Scientists identify potential dual-acting therapeutic strategy for aggressive form of breast cancer

A promising new combination therapy for a particularly aggressive form of breast cancer has been identified by Weizmann Institute scientists, as was recently reported in Cancer Research. [More]
Simple, coordinated approach can improve chances of survival for high-risk AML patients

Simple, coordinated approach can improve chances of survival for high-risk AML patients

New research shows that quickly identifying patients with high-risk acute myeloid leukemia (AML), and speeding the process to find them a stem cell donor and performing the transplant earlier, can significantly improve their chances of surviving for at least two years after diagnosis without a relapse. [More]
New report estimates global burden of cancer cases and deaths in 2015

New report estimates global burden of cancer cases and deaths in 2015

In 2015, there were an estimated 17.5 million cancer cases around the globe and 8.7 million deaths, according to a new report from the Global Burden of Disease Cancer Collaboration published online by JAMA Oncology. [More]
Clonal hematopoiesis may help predict cancer patients at risk for fatal form of leukemia

Clonal hematopoiesis may help predict cancer patients at risk for fatal form of leukemia

Patients successfully treated for breast, colon and other cancers can go on to develop an often-fatal form of leukemia, sometimes years after completion of treatment, due to a genetic mutation leading to secondary malignancies known as therapy-related myeloid neoplasms (t-MNs). [More]
Study reveals new way to improve stability of common protein drugs

Study reveals new way to improve stability of common protein drugs

Gaining access to important biopharmaceuticals needed to treat illnesses and autoimmune diseases is one of the biggest obstacles developing countries face. [More]
New study finds smoking cessation at any age reduces risk of death

New study finds smoking cessation at any age reduces risk of death

Tobacco use continues to be a major cause of cancer and premature death. Most studies of cigarette smoking and mortality have focused on middle-aged populations, with fewer studies examining the impact of tobacco cessation on disease and mortality risk among the elderly. [More]
Study sheds light on why new drug is effective in combating leukaemia

Study sheds light on why new drug is effective in combating leukaemia

Researchers at the University of Southampton have shed new light on why and how a new class of drug is effective at fighting off leukaemia. [More]
Preventative strategy in stem cell transplant recipients may help thwart C. diff infections

Preventative strategy in stem cell transplant recipients may help thwart C. diff infections

It may be possible to safely prevent one of the most common - and costly to treat - infections contracted by hospitalized patients undergoing bone marrow transplantation for the treatment of blood cancers, according to a study from the Abramson Cancer Center at the University of Pennsylvania. [More]
TUM scientists uncover molecular mechanisms of inhibitors that can selectively thwart immunoproteasome

TUM scientists uncover molecular mechanisms of inhibitors that can selectively thwart immunoproteasome

The immunoproteasome dismantles proteins and the resulting fragments are displayed on the surface of cells. This helps the immune system to recognize abnormal cells. However, in chronic inflammations and autoimmune diseases this “information channel” is overactive. [More]
Researchers reveal mechanism for side effects of drug used for treating hematological malignancies

Researchers reveal mechanism for side effects of drug used for treating hematological malignancies

A team of Japanese researchers revealed the mechanism for side effects such as fever and bone pain caused by G-CSF, which is widely used for peripheral blood hematopoietic stem cell harvesting (PBSCH). [More]
Cancer gene mutations can predict response to less intensive treatment in AML patients

Cancer gene mutations can predict response to less intensive treatment in AML patients

Patients with the most lethal form of acute myeloid leukemia (AML) - based on genetic profiles of their cancers - typically survive for only four to six months after diagnosis, even with aggressive chemotherapy. [More]
HSCI researchers use color tagging system to track development of blood stem cells

HSCI researchers use color tagging system to track development of blood stem cells

Harvard Stem Cell Institute (HSCI) researchers have used a colorful, cell-labeling technique to track the development of the blood system and trace the lineage of adult blood cells travelling through the vast networks of veins, arteries, and capillaries back to their parent stem cell in the marrow. [More]
Researchers uncover new clues that may help combat leukemia and other B cell cancers

Researchers uncover new clues that may help combat leukemia and other B cell cancers

When B lymphocytes (a type of white blood cell in the immune system geared for fighting diseases) turn cancerous, they become part of the problem, and need to be eliminated. [More]
New color-coding tool sheds light on blood disorders, cancers by tracking clonal stem cells

New color-coding tool sheds light on blood disorders, cancers by tracking clonal stem cells

A new color-coding tool is enabling scientists to better track live blood stem cells over time, a key part of understanding how blood disorders and cancers like leukemia arise, report researchers in Boston Children's Hospital's Stem Cell Research Program. [More]
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