Linoleic Acid News and Research

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Linoleic acid (LA) is an unsaturated omega-6 fatty acid used in the biosynthesis of arachidonic acid (AA) and some prostaglandins. It is found in the lipids of cell membranes. It is abundant in many vegetable oils, especially safflower and sunflower oils. It is a colorless liquid.

High-fat diets' eye-opening impact: Study reveals link to retinal damage and bisretinoid accumulation

In this study, the effects of a high-fat diet on the formation of bisretinoids in photoreceptor cells were explored. The results showed that mice on a high-fat diet had increased levels of bisretinoids and retinol-binding protein 4, which are associated with metabolic dysregulation.

8 May 2023

Ketogenic diet: A metabolic makeover boosting immunity and battling inflammation

A recent study discusses alterations in the human metabolic fingerprint associated with the keto diet.

8 May 2023

What are the gastrointestinal benefits of consuming soybean?

In a recent review published in the journal Nutrients, researchers at Australia’s CSIRO reviewed existing literature on the nutritional implications of soy intake concerning the intestinal microbiome.

23 Apr 2023

Study compared the milk composition and nutritional status of omnivore milk donors and vegetarian lactating mothers

Researchers compared the nutritional status composition of omnivorous diet-abiding milk donors and vegetarian/vegan lactating women.

14 Apr 2023

Triglyceride cycling enables fatty acid modification

Fat molecules serve as energy storage for fat cells. They consist of three fatty acids attached to a backbone of glycerol.

3 Apr 2023

An overview of the anti-inflammatory effects of nuts

Researchers summarize existing literature on the effects of consuming nuts on biomarkers of inflammation and oxidative stress.

28 Feb 2023

Researchers identify plasma metabolomic markers for the Mediterranean diet among pregnant women

A recent study identifies blood metabolomic markers and metabolite panels linked to the Mediterranean diet in pregnant women.

17 Jan 2023

The role of omega-3 and omega-6 metabolites during pregnancy

Omega-3 and -6 fatty acids ingested through the diet are metabolized into bioactive compounds that influence inflammation. In a recent the journal Biomedicines study, scientists reviewed the existing literature and summarized their findings related to the role of omega-3 and omega-6 metabolites during pregnancy.

15 Jan 2023

Daily intake of almonds changes the metabolism to recover faster after exercise

A new randomized controlled trial showed that participants who daily ate 57g almonds over four weeks had a 69% higher level of the beneficial oxylipin molecule 12,13-dihydroxy-9Z-octadecenoic acid in their blood after a 90 minute session of eccentric exercise than control volunteers.

10 Jan 2023

Pocket feature in SARS-CoV-2 spike protein is present in all deadly coronaviruses, study reveals

Scientists have discovered why some coronaviruses are more likely to cause severe disease, which has remained a mystery, until now.

24 Nov 2022

Genetic background plays a role in regulating the metabolism of essential polyunsaturated fatty acids

Genetic background has an effect on the metabolism of the essential polyunsaturated fatty acids alpha-linolenic acid and linoleic acid, a recent study from the University of Eastern Finland shows.

21 Nov 2022

Does maternal psychological and biological stress affect the composition of human breast milk?

Researchers investigated the influence of biological and psychological postpartum maternal stress on human milk fatty acid composition through a prospective cohort study in Amsterdam.

30 Sep 2022

The potential of NMR-based blood profiling as a single-domain assay to simultaneously predict multidisease onset

Researchers explored the potential of a nuclear magnetic resonance spectroscopy-based metabolomic platform to estimate the risks for the onset of several medical conditions.

27 Sep 2022

Study reveals gut-brain circuits drive cravings for fatty foods

In a recent study published in the journal Nature, researchers explored the neural basis for fat preference and identified receptors and neuronal elements mediating its development.

11 Sep 2022

The features of the newly emerging SARS-CoV-2 Omicron BA.2.75 subvariant

Researchers evaluated all the features, especially the antigenic properties and transmission potential of SARS-CoV-2 Omicron sub-variant BA.2.75.

10 Aug 2022

Routine periodic fasting associated with lower hospitalization risk in patients with COVID-19

The main objective of a new prospective observational cohort study was to evaluate whether periodic fasting is linked with severe COVID-19 symptoms.

1 Aug 2022

Lipids in breastmilk may protect against metabolic disease later in life

A new study examines the lipid content in breastmilk and its association with NCDs later in life.

13 Jul 2022

Simulating molecular dynamics of SARS-CoV-2 spike variants in the locked conformation

Researchers retrieved the first-ever sequenced spike (S) protein structures of the original Wuhan-Hu 1 SARS-CoV-2 strain, the Alpha, Delta, Delta-plus variants, and Omicron sub-variants BA.1 and BA.2 and compared their structural and molecular level variations.

10 May 2022

Free fatty acid-binding pocket found to be preserved across spike proteins of beta coronaviruses

Researchers assessed the binding pocket of linoleic acid, an essential free-fatty acid in the receptor-binding domains of the spike protein of beta-coronaviruses.

26 Apr 2022

The response of four SARS-CoV-2 spike variants to linoleic acid removal

A recent paper depicted the differential allosteric response of the SARS-CoV-2 spike variants to linoleic acid.