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Study reveals non-coding genetic variants associated with Alzheimer’s disease functioning in microglia

Scientists studying Alzheimer's disease (AD) have identified thousands of genetic variants in the genome in the development of this progressive neurodegenerative disease.

23 Sep 2023

Scientists discover novel microglia-associated risk factors for Alzheimer's disease

Scientists studying Alzheimer's disease (AD) have identified thousands of genetic variants in the genome in the development of this progressive neurodegenerative disease.

22 Sep 2023

7 Tesla MRI reveals new insights into sleep regulation and light stimulation of the brain

A study conducted by researchers at the University of Liège (BE) Institute, using ultra-high field 7 Tesla MRI, are providing a better understanding of how sleep is regulated.

22 Sep 2023

How did COVID-19 pandemic restrictions impact invasive meningococcal disease trends?

The impact of COVID-19 pandemic restrictions on the incidence and strain distribution of meningococcus.

11 Sep 2023

Dangerous antibiotic-resistant bacteria found in China's ready-to-eat foods

The study reveals high levels of antibiotic-resistant Staphylococcus aureus (MRSA) in ready-to-eat foods across 25 provinces in China, posing a serious public health risk. The findings emphasize the need for stronger food safety measures, as the MRSA strains identified were resistant to multiple antibiotics and exhibited various virulence factors.

10 Sep 2023

Unlocking the genetic code of blood sugar reveals new diabetes risks and lung complications

The study used a genome-wide association study (GWAS) to analyze random glucose levels in nearly half a million non-diabetic subjects, uncovering 150 distinct genetic signals, including 53 new ones, linked to glycemic traits and type 2 diabetes. The research also discovered a causal effect of random glucose and type 2 diabetes on lung function, identifying lung dysfunction as a new diabetes complication.

10 Sep 2023

Study explores the role of sex on mRNA and protein levels and its genetic regulation in brain

Researchers investigated the impact of biological sex on protein levels and its genomic control by analyzing 1,277 proteomes of the brain.

4 Sep 2023

Gene variant protects against Alzheimer's and Parkinson's diseases

About one in every five people carries a version of a gene that, although largely unsung, appears to confer protection against both Alzheimer's disease and Parkinson's disease, Stanford Medicine investigators and their colleagues have learned.

30 Aug 2023

Maternal obesity linked to childhood weight issues through DNA changes

Boston Birth Cohort study finds that maternal pre-pregnancy obesity alters newborn DNA methylation, potentially increasing the risk of obesity in the child. The research targets high-risk U.S. demographics and could guide future interventions for childhood obesity.

27 Aug 2023

Taking adult education classes may help prevent dementia

How can we best keep our brain fit as we grow older? It's well known that regular cognitive activity, for example brainteasers, sudokus, or certain video games in middle and old age tends to protect against cognitive decline and dementias like Alzheimer's.

23 Aug 2023

Copy number profiling provides insight as to why prostate cancer may become lethal

Researchers performed genome-wide copy number profiling of the androgen receptor (AR) on metastases from deceased prostate cancer patients.

16 Aug 2023

Exploring DNA methylation biomarkers of multiple sclerosis

Researchers identify cell-specific DNA methylation signatures associated with MS.

14 Aug 2023

Lyme disease bacteria adapt to animal hosts at the variant level, study finds

A study looks at the mechanisms behind genetic variation in the bacteria that cause Lyme disease. Lyme disease is the most common vector-transmitted disease in the United States, with around 476,000 human cases annually.

8 Aug 2023

Can genome editing transform ocular disease treatment?

The discovery and development of gene-editing technologies and their applications in managing ocular diseases.

3 Aug 2023

Cerebellum plays a key role in generalized convulsive seizures, study finds

Recurrent seizures are debilitating and can sometimes, be fatal. The onset and presentation of seizures vary significantly among epilepsy patients. Of more than 25 categories of seizure presentations within epilepsy, those with motor convulsions are perhaps the most disruptive and generally most feared among patients and caregivers.

2 Aug 2023

Locus News and Research

Study reveals non-coding genetic variants associated with Alzheimer’s disease functioning in microglia

Scientists discover novel microglia-associated risk factors for Alzheimer's disease

7 Tesla MRI reveals new insights into sleep regulation and light stimulation of the brain

How did COVID-19 pandemic restrictions impact invasive meningococcal disease trends?

Dangerous antibiotic-resistant bacteria found in China's ready-to-eat foods

Unlocking the genetic code of blood sugar reveals new diabetes risks and lung complications

Study explores the role of sex on mRNA and protein levels and its genetic regulation in brain

Gene variant protects against Alzheimer's and Parkinson's diseases

Maternal obesity linked to childhood weight issues through DNA changes

Taking adult education classes may help prevent dementia

Copy number profiling provides insight as to why prostate cancer may become lethal

Exploring DNA methylation biomarkers of multiple sclerosis

Lyme disease bacteria adapt to animal hosts at the variant level, study finds

Can genome editing transform ocular disease treatment?

Cerebellum plays a key role in generalized convulsive seizures, study finds

What are the mediators linking cardiometabolic risk factors and severe COVID-19?

Insights into the relationship between COVID-19 and mental health

How do De novo sequencing, QTL mapping, WGS, and lcWGS empower breakthroughs in agrigenomics

Japanese researchers identify genetic quirk linked to severe COVID-19

Researchers demonstrate targeted epigenome editing in the promoter region of several genes using sgRNA/dCas9 complexes

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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