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Possible treatment for the fatal lung disease idiopathic pulmonary fibrosis

They found that the anti-cancer drug imatinib mesylate — commercially known as Gleevec and produced by Novartis Pharmaceuticals — can target a gene critical to controlling the disease process. Previously, there had been no treatment and patients usually did not survive beyond three years of diagnosis. Now the treatment is undergoing clinical trials at Mayo Clinic.

2 Nov 2004

Cigarette smoking can dramatically affect appetite and weight control

The study by researchers in the Department of Pharmacology and the CRC for Chronic Inflammatory Diseases found that mice exposed to four days of cigarette smoke displayed significant loss of appetite, fat tissue and body weight.

1 Nov 2004

Lag-3 gene dampens immune responses by controlling regulatory T-cell function

The discovery that the Lag-3 gene acts as a brake to prevent immune system responses from running out of control solves a mystery that has puzzled researchers since the gene was discovered 14 years ago.

22 Oct 2004

New antibody to prevent respiratory syncytial virus in premature babies

Virginia Commonwealth University researchers are studying the effectiveness of introducing a new antibody in premature infants to manage the most common form of lower respiratory tract infections in children worldwide.

21 Oct 2004

Asthma research company Synairgen to float on London's Alternative Investment Market

A spin-out company from the University of Southampton specialising in finding and out-licensing treatments for chronic bronchitis (COPD) and the severest forms of asthma, is about to seek a listing on London's Alternative Investment Market (AIM).

13 Oct 2004

Some people who chew betel nut may be genetically more prone to mouth cancer

The nut of the betel or areca palm tree contains a mild, central nervous system stimulant called arecoline. Chewing the nut on its own or with a mixture of tobacco, lime and betel leaf is a popular habit in Asian countries and among British Asians.

12 Oct 2004

New statement published on nonmalignant diseases related to asbestos exposure

In its first official statement since 1986 on the topic, the American Thoracic Society (ATS) has published a document entitled “Diagnosis and Initial Management of Nonmalignant Diseases Related to Asbestos.”

4 Oct 2004

Master gene that controls the first breath a newborn infant

Researchers at Cincinnati Children's Hospital Medical Center have identified a master gene that controls the first breath a newborn infant takes. The findings could have implications for treating premature babies and children and adults with lung disease or lung injury.

28 Sep 2004

Link between eosinophils and asthma

Mayo Clinic researchers have used a comparative genomic strategy to demonstrate a causative link between eosinophils, a rare type of white blood cell, and asthma.

18 Sep 2004

Cancer survivors' other medical problems poorly managed

People who survive cancer are less likely to receive necessary care for a wide range of other non-cancer-related medical problems according to a new study published September 13, 2004 in the online edition of CANCER, a peer- reviewed journal of the American Cancer Society.

12 Sep 2004

Program that targets allergens and tobacco smoke in the home resulted in fewer asthma symptoms in children

A program that targets allergens and tobacco smoke in the home resulted in fewer asthma symptoms in children participating in the intervention than in those who were not, according to a new study sponsored by the National Institutes of Health (NIH) in seven metropolitan areas nationwide.

10 Sep 2004

Genetically modified fish may help treat hemophiliacs

A human blood-clotting factor used to treat some people with haemophilia and accident victims suffering serious bleeding has been produced using genetically modified fish.

9 Sep 2004

Study aims for long term impact to help inner-city children with asthma

A study designed to reduce the levels of indoor allergens – conducted in the homes of inner-city children with asthma – resulted in fewer asthma exacerbations and unscheduled visits for asthma during a two-year period, according to a UT Southwestern Medical Center at Dallas researcher who participated in the multicenter study.

8 Sep 2004