Lung Transplant News and Research

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A pulmonary transplant (or lung transplant) is a surgical procedure in which a diseased lung is removed and replaced with a healthy lung from a donor. A lung transplant will often be recommended if a person has advanced lung disease that is unresponsive to other treatments and/or when a person's life expectancy is likely less than 2-3 years. A lung transplant is considered for those suffering from the following conditions:

Study demonstrates unexpected electrical changes in first successful transplant of genetically-modified pig heart

Ten months after transplanting the first genetically-modified pig heart into a human patient, University of Maryland School of Medicine researchers continue to report on new findings from the landmark transplant.

14 Nov 2022

Favorable survival outcomes among COVID-19 lung transplant recipients

The survival rate of lung transplant recipients with COVID-19 respiratory failure was not significantly different than other patients.

16 Oct 2022

Clinical trial to test the safety, efficacy of bacteriophages for treating P. aeruginosa infections in CF patients

Cystic fibrosis (CF) is an inherited disorder that causes severe damage to the lungs and other organs in the body.

11 Oct 2022

Healthy people over 65 years of age recommended to get a heart check-up before non-cardiac surgery

A heart check-up is recommended in even apparently healthy people over 65 years of age before intermediate- or high-risk non-cardiac surgery, according to European Society of Cardiology (ESC) Guidelines on cardiovascular assessment and management of patients undergoing non-cardiac surgery published online today in European Heart Journal.

26 Aug 2022

Lung transplantation at Cedars-Sinai has outstanding success rates

A new report on lung transplantation success rates confirms that Cedars-Sinai patients experienced one-year survival outcomes of 91.49%, an achievement above the national average of 89.46%.

15 Aug 2022

Combination therapy regimen for cystic fibrosis is also beneficial to primary school-aged children

Cystic fibrosis remains an incurable genetic disorder which impairs lung function and significantly reduces life expectancy.

8 Aug 2022

Study offers insight into the basic cellular pathologies driving interstitial lung disease

While most people recover from COVID-19 within a week or two, up to one-third of survivors experience persistent or new symptoms weeks and months after initial infection.

21 Jul 2022

Zinc may reverse lung damage, improve survival for patients with idiopathic pulmonary fibrosis

Investigators from the Women's Guild Lung Institute at Cedars-Sinai have discovered that zinc, a common mineral, may reverse lung damage and improve survival for patients with a deadly age-related condition known as idiopathic pulmonary fibrosis (IPF).

8 Jun 2022

Aston University’s new antibiotic combination forms part of a lifesaving treatment for cystic fibrosis

A new antibiotic combination developed by researchers at Aston University has formed part of a lifesaving treatment used in the USA.

26 May 2022

A step-by-step plan to create a digital twin of the human immune system

An article published May 20 in Nature Digital Medicine provides a step-by-step plan for an international effort to create a digital twin of the human immune system.

20 May 2022

Researchers use bacteriophages to treat antibiotic-resistant mycobacterial lung infection

For the first time, researchers have successfully used bacteriophages – viruses that kill bacteria – to treat an antibiotic-resistant mycobacterial lung infection, clearing the way for a young National Jewish Health patient with cystic fibrosis to receive a life-saving lung transplant.

13 May 2022

Clinical characteristics of immunocompromised patients infected with the SARS-CoV-2 Omicron variant

Researchers examined the characteristics and outcomes of COVID-19 in immunocompromised patients.

29 Apr 2022

Researchers reveal possible way to treat newborns with rare genetic lung condition

When babies are born with alveolar capillary dysplasia with misalignment of pulmonary veins (ACDMPV), their skin starts to turn blue from the under-oxygenated blood in their systems.

19 Apr 2022

Study shows the viability of lung transplants in patients with COVID-19-associated ARDS

Patients with COVID-19-associated acute respiratory distress syndrome who received lung transplants had similar outcomes, compared to transplant patients without COVID-19, according to a Northwestern Medicine study published in JAMA.

2 Mar 2022

Gut enzymes open a gateway to create universal blood-type donor organs

A study published in Science Translational Medicine performed at the Latner Thoracic Surgery Research Laboratories and UHN's Ajmera Transplant Centre has proved that it is possible to convert blood type safely in donor organs intended for transplantation.

16 Feb 2022

NIH grant renewal will enable Nebraska scientist to advance research on virtual immune system

The renewal of a National Institutes of Health grant will enable a University of Nebraska-Lincoln researcher to continue developing a tool that illuminates the complex, multi-scale interplay of the immune system's many components.

8 Feb 2022

Post-transplantation lung microbiome profiles can provide prognostic information

Lung transplantation is a life-saving intervention in cases of severe respiratory failure. A feared and common complication following a lung transplant is chronic deterioration in lung function (CLAD/Chronic Lung Allograft Dysfunction).

7 Feb 2022

Study shows positive outcomes in COVID-19 patients who underwent lung transplants

For many COVID-19 patients with irrecoverable lung damage, transplantation is the only option for survival. However, there is limited information about the long-term outcomes of these patients, including postoperative complications, hospital length of stay and survival.

3 Feb 2022

Researchers identify genetic cause of rare interstitial lung disease in a young child

New research from Washington University School of Medicine in St. Louis has solved the medical mystery of why a 2-year-old child — seemingly healthy at birth — succumbed to an undiagnosed, rare illness.

31 Jan 2022

Cedars-Sinai experts conduct a national analysis on COVID-19 lung transplants

The analysis of more than 3,000 lung transplants in the U.S. between Aug. 1, 2020, and Sept. 30, 2021, showed that during the pandemic, 7% of the nation's lung transplants were performed to treat severe, irreversible lung damage caused by COVID-19. More than half of these patients needed ventilators or extracorporeal membrane oxygenation, or ECMO, before their transplant.

27 Jan 2022