Lymph Nodes News and Research

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Combination treatment shows promise for aggressive subtype of non-Hodgkin lymphoma

Nearly 90 percent of patients with an aggressive subtype of non-Hodgkin lymphoma had their cancer go into remission in a small phase 2 clinical trial testing a treatment aimed at making chemotherapy more effective, according to Weill Cornell Medicine and NewYork-Presbyterian investigators.

5 May 2023

HIV status does not affect Tecovirimat treatment outcomes for Mpox virus infection

A retrospective cohort study comparing the clinical presentation and treatment outcomes of people with HIV and those without HIV who were treated with tecovirimat for confirmed mpox virus infection. The study found that HIV status did not seem to affect treatment outcomes.

4 May 2023

Testing hundreds of existing therapeutics to fight blood cancer more effectively

Multiple myeloma is a rare blood cancer caused by the uncontrolled multiplication of abnormal plasma cells.

27 Apr 2023

NCCN releases new guidelines to help patients understand inflammatory breast cancer

Today, the National Comprehensive Cancer Network has published a new addition to its library of patient resources, expanding the information available for breast cancer.

24 Apr 2023

New $2.3 million NCI grant awarded to Georgia Cancer Center to improve survival of patients with AML

Acute myeloid leukemia (AML) is a cancer that affects blood cells in the bone marrow -; the spongy tissue inside certain bones, where new blood cells are made.

17 Apr 2023

Experimental mRNA vaccine plus an immunotherapy reduced the likelihood of melanoma recurrence

The combination of an experimental mRNA vaccine with an immunotherapy reduced the likelihood of melanoma recurring or causing death by 44% when compared to immunotherapy alone, a new clinical trial shows.

17 Apr 2023

The emergence of tanapox in South Africa, 2022

Study describes a human case of tanapox in South Africa.

10 Apr 2023

Regulatory T cell populations descend from two different origins, finds study

A regulatory class of human T cells descends from two different origins, one that relates to autoimmunity and one that relates to protective immunity, according to a new study led by Children's Hospital of Philadelphia (CHOP).

7 Apr 2023

Study explores the association between gut microbiome dysbiosis and uveitis

Researchers provide an overview of existing research on the correlation between uveitis and gut dysbiosis.

7 Apr 2023

Formerly incarcerated persons have higher health risks than the general population

In 2012, Michael Cruz exercised a lot. Four years into a 15-year prison sentence, this was one of the only things he had, he says, until he noticed a numb, tingling sensation in one of his toes while working out.

3 Apr 2023

Study paves the way for some patients with testicular cancer to avoid chemotherapy and radiation

A newly published study paves the way for some patients with testicular cancer to avoid chemotherapy and radiation.

30 Mar 2023

Diverse subset of T-cell clones plays a role in the antitumor effects of immune checkpoint inhibitors

Immune checkpoint inhibitors (ICIs) are widely sought after for the treatment of different types of cancers. Unfortunately, only 20–30% patients with cancer respond to ICI treatment.

29 Mar 2023

Drugs to activate STING could help prevent cancer metastasis

A team of scientists at the Sloan Kettering Institute have identified the STING cellular signaling pathway as a key player in keeping dormant cancer cells from progressing into aggressive tumors months, or even years, after they've escaped from a primary tumor.

29 Mar 2023

Scientists identify a distinct role of retinoic acid during immune response of the gut

A team of scientists from the Renaissance School of Medicine at Stony Brook University have identified a distinct role of retinoic acid, a metabolite of vitamin A, during the immune response of the gut.

28 Mar 2023

Novel subset of memory B cells predicts long-lived antibody responses to influenza vaccination

Memory B cells play a critical role to provide long-term immunity after a vaccination or infection. In a study published in the journal Immunity, researchers describe a distinct and novel subset of memory B cells that predict long-lived antibody responses to influenza vaccination in humans.

22 Mar 2023

Leaving lymph nodes intact until after immunotherapy could boost efficacy against solid tumors

Cancer treatment routinely involves taking out lymph nodes near the tumor in case they contain metastatic cancer cells.

20 Mar 2023

Ipsilateral vaccination improves response to second dose of COVID-19 vaccine

Researchers examine whether the involvement of the ipsilateral or contralateral lymph nodes affected the immune response during sequential vaccination.

16 Mar 2023

Host immune system forms small lesions in the intestines in response to bacterial infection

Yersinia bacteria cause a variety of human and animal diseases, the most notorious being the plague, caused by Yersinia pestis.

14 Mar 2023

Bispecific antibody shows improved efficacy against SARS-CoV-2 variants

Researchers from The University of Texas MD Anderson Cancer Center have developed fully human bispecific antibodies, as revealed in a recent study. These antibodies can bind to two distinct epitopes of the receptor binding domain (RBD) of the SARS-CoV-2 spike protein and have demonstrated the ability to neutralize various strains of the virus, including the Omicron variant.