Lymph Nodes News and Research

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Clinical study: Higher radiation dose does not improve overall survival for NSCLC

A higher dose of radiation (74 Gy) does not improve overall survival for non-small cell lung cancer that has spread to the lymph nodes, compared to the standard radiation dose (60 Gy), according to an interim analysis of a late-breaking randomized study presented at the plenary session, October 3, 2011, at the 53rdAnnual Meeting of the American Society for Radiation Oncology.

4 Oct 2011

Three Penn labs receive NIH grant to speed translation of medical research into patient care

Three labs from the University of Pennsylvania have received $12.5 million from the National Institutes of Health (NIH) as part of its $143.8 million national grant program to challenge the scientific status quo with innovative ideas that have the potential to speed the translation of medical research into improved health for the American public.

4 Oct 2011

Virtual 18F-FDG PET/CT bronchoscopy may accurately detect NSCLC metastases

For patients with non-small cell lung cancer (NSCLC) the accurate determination of the lymph node status before therapy is critical to develop an individualized treatment plan. Research from the October issue of the Journal of Nuclear Medicine highlights a new way for this information to be collected -- a virtual fly-through three-dimensional 18F-FDG PET/computed tomography (FDG-PET/CT) bronchoscopy that has high diagnostic accuracy for the detection of regional lymph node metastases.

4 Oct 2011

Prototype drug shows promise against chronic lymphocytic leukemia

Pre-clinical research has generated some very promising findings about a prototype drug for the treatment of chronic lymphocytic leukemia.

29 Sep 2011

Scientists discover how liver destroys immune T-cells

Scientists at the Centenary Institute in Sydney have seen for the first time (in mice) how the liver goes independent, engulfing and destroying the body's defence troops-T-cells.

20 Sep 2011

Study finds high prevalence of lymph node evaluation for colon cancer

During the past two decades there has been a significant increase in the percentage of patients who have a high number of lymph nodes evaluated during colon cancer operations, but this improvement is not associated with an increase in the overall proportion of colon cancers that are node positive, according to a study in the September 14 issue of JAMA.

14 Sep 2011

Breast-conservation therapy and mastectomy provide similar survival rates for early-stage breast cancer

Young women with early-stage breast cancer have similar survival rates with a lumpectomy and radiation treatment, known as breast-conservation therapy, as with mastectomy, a new study conducted at the University of Maryland has found. The results of the analysis of nearly 15,000 patients listed in a nationwide cancer registry will be presented at the 2011 Breast Cancer Symposium to be held Sept. 8-11 in San Francisco.

8 Sep 2011

New guidelines for treatment of melanoma

Based on an extensive review of scientific literature and the recommendations of recognized melanoma experts, the American Academy of Dermatology (Academy) has released updated evidence-based guidelines for the treatment of melanoma, the deadliest form of skin cancer.

8 Sep 2011

Breast cancer patients with BRCA1 mutation experience pCR after neoadjuvent chemotherapy

Nearly half of breast cancer patients carrying the BRCA1 gene mutation experience a complete pathological response (pCR) - the disappearance of all evidence of disease from the breast tissue and lymph nodes - regardless of disease stage after standard neoadjuvent chemotherapy, according to new research from The University of Texas MD Anderson Cancer Center.

7 Sep 2011

Researchers discover protein signals responsible for preserving anti-viral antibodies

Our immune system is capable of a remarkable feat: the ability to remember infections for years, even decades, after they have first been encountered and defeated. While the antibodies we make last only about a month, we retain the means of making them for a lifetime.

3 Sep 2011

SWOG selects four cancer researchers for 2011 Young Investigator Training Course

SWOG has selected four talented, early-career researchers for its 2011 Young Investigator Training Course. These four will attend a three-day workshop September 19 - 21 in Seattle, Wash., for intensive training in how to design and conduct cancer clinical trials.

3 Sep 2011

Patients with sarcopenia more likely to have worse outcomes from melanoma

It's not how old but how frail patients are that can predict how well they will fare after a melanoma diagnosis. In fact, young patients in poor health may have worse outcomes than older patients in good shape.

31 Aug 2011

GCC hormone receptor may also help fight obesity

The hormone receptor guanylyl cyclase C (GCC) has been established as a suppressor of colorectal cancer tumors, but new evidence from Thomas Jefferson University suggests it may also help fight one of the country's biggest pandemics: obesity.

26 Aug 2011

Seattle Genetics receives FDA approval for Adcetris to treat Hodgkin lymphoma, ALCL

The U.S. Food and Drug Administration today approved Adcetris to treat Hodgkin lymphoma and a rare lymphoma known as systemic anaplastic large cell lymphoma.

20 Aug 2011

Insight into how HIV reservoirs may form

Much like cities organize contingency plans and supplies for emergencies, chronic infectious diseases like HIV form reservoirs that ensure their survival in adverse conditions. But these reservoirs-small populations of viruses or bacteria of a specific type that persist despite attack by the immune system or drug treatment-are not always well understood.

18 Aug 2011

Neoprobe sells gamma detection device business to Devicor

Neoprobe Corporation, a diversified developer of innovative oncology surgical and diagnostic products, announced today that it completed the previously announced sale of its neoprobe GDS line of gamma detection device systems to Devicor Medical Products, Inc. for $30 million in upfront consideration, plus up to an additional $20 million in royalties based on Devicor's achievement of certain revenue milestones.

18 Aug 2011

IMRT produces high response rate in patients with extranodal lymphoma of head and neck: Research

Lymphoma is a cancer that affects organs of the immune system, including the lymph nodes. In a subtype of the disease called extranodal lymphoma, tumors arise in non-lymphoid organs, such as the tongue and tonsils.

16 Aug 2011

Combination immunotherapy more effective for patients with Sezary Syndrome

A three-pronged immunotherapy approach nearly doubles five-year survival among patients with rare leukemic form of cutaneous T-cell lymphoma, reports a new study by dermatologists from the Abramson Cancer Center and Perelman School of Medicine at the University of Pennsylvania.

16 Aug 2011

Neoprobe seeks FDA marketing approval of Lymphoseek for use in ILM oncology procedure

Neoprobe Corporation, a diversified developer of innovative oncology surgical and diagnostic products, today announced it has submitted a New Drug Application (NDA) for Lymphoseek to the U.S. Food and Drug Administration.

11 Aug 2011

HPV-related throat cancer cases increase sharply over the past 10 years

Forty-two-year-old Manahawkin, New Jersey resident David Caldarella can recite a long list of dates off the top of his head. The first one starts with the day he found a lump on the right side of his neck while shaving. It was March 23, 2010. Caldarella immediately called his physician.

8 Aug 2011

Lymph Nodes News and Research

Clinical study: Higher radiation dose does not improve overall survival for NSCLC

Three Penn labs receive NIH grant to speed translation of medical research into patient care

Virtual 18F-FDG PET/CT bronchoscopy may accurately detect NSCLC metastases

Prototype drug shows promise against chronic lymphocytic leukemia

Scientists discover how liver destroys immune T-cells

Study finds high prevalence of lymph node evaluation for colon cancer

Breast-conservation therapy and mastectomy provide similar survival rates for early-stage breast cancer

New guidelines for treatment of melanoma

Breast cancer patients with BRCA1 mutation experience pCR after neoadjuvent chemotherapy

Researchers discover protein signals responsible for preserving anti-viral antibodies

SWOG selects four cancer researchers for 2011 Young Investigator Training Course

Patients with sarcopenia more likely to have worse outcomes from melanoma

GCC hormone receptor may also help fight obesity

Seattle Genetics receives FDA approval for Adcetris to treat Hodgkin lymphoma, ALCL

Insight into how HIV reservoirs may form

Neoprobe sells gamma detection device business to Devicor

IMRT produces high response rate in patients with extranodal lymphoma of head and neck: Research

Combination immunotherapy more effective for patients with Sezary Syndrome

Neoprobe seeks FDA marketing approval of Lymphoseek for use in ILM oncology procedure

HPV-related throat cancer cases increase sharply over the past 10 years

Immunology eBook

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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