Mammary Gland News and Research

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Novel amyloid protein that induces amyloidosis discovered

A collaboration led by scientists at Tokyo University of Agriculture and Technology, Japan, has discovered a novel amyloid protein that induces amyloidosis in rats.

25 Oct 2019

Research: Metformin may be effective in treating breast cancer that lacks Nischarin protein

Research conducted by Suresh Alahari, PhD, Professor of Biochemistry and Genetics at LSU Health New Orleans School of Medicine, has found that metformin, a commonly prescribed drug for Type 2 Diabetes, may be effective in treating cancers that lack a protein called Nischarin.

20 Sep 2019

Nicotinamide riboside supplementation confers significant physiological benefits to mothers and offspring

ChromaDex Corp. today reported that results of a first-of-a-kind preclinical study on lactation have shown that supplementation with the unique B3 vitamin nicotinamide riboside confers significant and enduring physiological benefits to mothers and offspring.

23 Jan 2019

New enzyme biomarker test indicates diseases and bacterial contamination

Researchers at Queen's University Belfast have developed a highly innovative new enzyme biomarker test that has the potential to indicate diseases and bacterial contamination saving time, money and possibly lives.

18 Jan 2019

Study highlights efforts to address widespread PFAS contamination in drinking water

A new analysis shows variation in the way state and federal regulators manage PFAS contaminants in drinking water, with some states adopting guideline levels that are more health protective than the non-enforceable levels set by the U.S. Environmental Protection Agency.

9 Jan 2019

Study finds large disparities in U.S. drinking water guidelines

In response to the growing problem of drinking water contaminated with per- and poly-fluoroalkyl substances, a new analysis shows that many states are establishing their own guideline levels for two types of PFAS--PFOA and PFOS--that differ from federal guidelines.

8 Jan 2019

Research uncovers how sleeping stem cells in the mammary gland are awakened at puberty

Walter and Eliza Hall Institute researchers have discovered how the growth of milk-producing mammary glands is triggered during puberty. Sleeping stem cells in the mammary gland are awoken by a protein dubbed FoxP1, according to the research that was published today in the journal Developmental Cell.

25 Oct 2018

Study identifies molecular switch that controls fate of milk-producing breast cells

A research team, led by investigators from Georgetown Lombardi Comprehensive Cancer Center, details how a natural and dramatic process -- changes in mammary glands to accommodate breastfeeding -- uses a molecular process believed to contribute to survival of pre-malignant breast cells.

15 Oct 2018

Targeting a protein could be key for suppressing breast cancer metastasis, study suggests

A new study by University of Kentucky Markey Cancer Center researchers suggests that targeting a protein known as collagen XIII could be key for suppressing breast cancer metastasis.

9 Oct 2018

Protein involved in milk production appears to stimulate growth and spread of breast cancer

VCU Massey Cancer Center researchers have identified a protein involved in milk production that stimulates the growth and spread of breast cancer and could ultimately serve as a target for novel therapies to treat breast cancer.

12 Sep 2018

Scientists uncover reason for similarity between cells in malignant cancers and embryonic cells

Using just a microscope, Italian surgeon Francesco Durante was struck by the similarities between cells in the most malignant cancers and the embryonic cells of the organ in which the cancer originated.

9 Aug 2018

Study uncovers how a sticky protein promotes activity of estrogen in breast cancer cells

New research uncovers how a sticky protein called fibronectin promotes the activity of estrogen in breast cancer cells.

9 Jul 2018

Inhibiting epigenetic proteins with drugs could prevent development of breast cancer

Researchers at the Princess Margaret Cancer Centre in Toronto have discovered that epigenetic proteins promote the proliferation of mammary gland stem cells in response to the sex hormone progesterone.

19 Jun 2018

Researchers identify mechanisms that regulate mammary gland development

Publication in Nature Cell Biology: researchers at the Université libre de Bruxelles, ULB define for the first time the mechanisms responsible for the mammary gland development.

23 May 2018

Researchers report new signaling exchange that mediates normal mammary gland development

The human body develops most tissue types during fetal development, in a mother's uterus. Yet one only tissue develops after birth: the mammary gland.

18 May 2018

Study: Macrophages play key role in maintaining stem cell niche of mammary gland

A new study finds that one of the toughest characters in the immune system, the macrophage, has a nurturing side, at least when it comes to guarding the developing breast.

18 May 2018

Disruption of the body's circadian rhythm linked to increased risk of breast cancer

For years, doctors have associated the BRCA1 and BRCA2 gene mutations with an increased risk of breast cancer.

9 May 2018

Researchers uncover new way to treat aggressive breast tumors

Researchers at Lund University and Karolinska Institutet have uncovered a way to treat aggressive breast tumors through manipulation of the connective tissue cells of the tumor.

13 Mar 2018

UC scientists identify protein that acts as mediator of HER2-driven breast cancer

Researchers at the University of Cincinnati College of Medicine have identified for the first time that the estrogen receptor-binding protein MED1 is a critical mediator of HER2-driven breast cancer, identifying it as a potential therapeutic target.

9 Jan 2018

Macrophages play major role in helping early breast cancer cells spread even before tumor develops

Mount Sinai researchers have discovered that normal immune cells called macrophages, which reside in healthy breast tissue surrounding milk ducts, play a major role in helping early breast cancer cells leave the breast for other parts of the body, potentially creating metastasis before a tumor has even developed, according to a study published in Nature Communications.

2 Jan 2018