Marburg Virus News and Research

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Marburg virus or simply Marburg is the common name for the the genus of viruses Marburgvirus, which contains one species, ''Lake Victoria marburgvirus''. The virus causes the disease Marburg Hemorrhagic Fever (MHF), also referred to as ''Marburg Virus Disease''.

Antiviral agent protects rhesus monkeys from deadly Ebola virus

Rhesus monkeys were completely protected from the deadly Ebola virus when treated three days after infection with a compound that blocks the virus's ability to replicate. These encouraging preclinical results suggest the compound, known as GS-5734, should be further developed as a potential treatment, according to research findings to be presented tomorrow at the IDWeek conference.

12 Oct 2015

Health Partnership Scheme funds project dedicated to viral haemorrhagic fever

A team from Plymouth University Peninsula Schools of Medicine and Dentistry and Plymouth Hospitals NHS Trust has received funding of £136,000 from the Health Partnership Scheme to develop a training programme to help the Sierra Leonean Health Service to fight future outbreaks of viral haemorrhagic fever.

1 Oct 2015

Researchers develop chip-based instrument for reliable detection of Ebola virus

A team led by researchers at UC Santa Cruz has developed chip-based technology for reliable detection of Ebola virus and other viral pathogens. The system uses direct optical detection of viral molecules and can be integrated into a simple, portable instrument for use in field situations where rapid, accurate detection of Ebola infections is needed to control outbreaks.

25 Sep 2015

Harvard Medical School scientists reveal structure of vesicular stomatitis virus protein

Viruses need us. In order to multiply, viruses have to invade a host cell and copy their genetic information. To do so, viruses encode their own replication machinery or components that subvert the host replication machinery to their advantage.

3 Jul 2015

TSRI-led study identifies new immune molecules that protect against Marburg virus

A new study led by scientists at The Scripps Research Institute identifies new immune molecules that protect against deadly Marburg virus, a relative of Ebola virus. The research provides ingredients needed to develop treatments for future Marburg outbreaks.

30 Jun 2015

New study reveals key part of Ebola virus life cycle at higher resolution than ever before

A new study led by scientists at The Scripps Research Institute (TSRI) reveals a key part of the Ebola virus life cycle at a higher resolution than ever before. The research sheds light on how Ebola virus assembles—and how researchers might stop the often-fatal infection.

26 Jun 2015

Researchers show how human antibodies can neutralize Marburg virus

Researchers at Vanderbilt University, the University of Texas Medical Branch at Galveston and The Scripps Research Institute for the first time have shown how human antibodies can neutralize the Marburg virus, a close cousin to Ebola.

27 Feb 2015

TSRI scientists show how to target weak spots of Marburg virus with future treatments

Marburg virus is Ebola's deadly cousin. The virus is up to 90 percent lethal—and doctors are desperate for tools to fight it.

27 Feb 2015

Researchers reveal how human immune system can fight against deadly Marburg virus

A collaborative team from The University of Texas Medical Branch at Galveston, Vanderbilt University and The Scripps Research Institute have identified mechanisms involved in antibody response to the deadly Marburg virus by studying the blood of a Marburg survivor.

27 Feb 2015

Study: Airport screening for disease often misses infected travellers, but can be improved

Scientists have shown that airport screening for disease will often miss half or more of infected travellers, but can be improved by customizing to pathogens.

23 Feb 2015

Experimental Ebola vaccine safe and immunogenic in African population

Two experimental DNA vaccines to prevent Ebola virus and the closely related Marburg virus [1] are safe, and generated a similar immune response in healthy Ugandan adults as reported in healthy US adults earlier this year.

23 Dec 2014

New study finds that it is possible to distinguish between different hemorrhagic fevers

A new study has found it is possible to distinguish between different hemorrhagic fevers, including Marburg (Ebola cousin) and Lassa before the person becomes symptomatic.

11 Nov 2014

Research findings could pave way for new treatments against filoviruses

Filoviruses like Ebola "edit" genetic material as they invade their hosts, according to a study published this week in mBio, the online open-access journal of the American Society for Microbiology.

5 Nov 2014

Profectus BioSciences gets funding to develop VesiculoVax Zaire-Ebola virus vaccine

Profectus BioSciences, Inc., a clinical-stage vaccine company developing novel vaccines for the treatment and prevention of infectious diseases, announced today that the Department of Defense through the Medical Countermeasure Systems-Joint Vaccine Acquisition Program, a subordinate command of the Joint Program Executive Office for Chemical and Biological Defense, Edgewood, MD, has contracted the manufacture and IND-enabling preclinical testing of the Profectus trivalent Ebola/Marburg vaccine.

31 Oct 2014

NIAID announces license agreement to develop dual-purpose candidate vaccines for rabies, Ebola

The National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, today announced a new license agreement aimed at advancing dual-purpose candidate vaccines to protect against rabies and Ebola viruses.

17 Oct 2014

Statement on Ebola epidemic

The Ebola virus is spreading rapidly and to an unexpected extent. The outbreak does not follow the patterns experienced in the past and the virus shows a new disease dynamic in regions, where it has never been recorded before. For this reason, the German National Academy of Sciences Leopoldina, acatech – the German Academy of Science and Engineering, and the Union of the German Academies of Sciences and Humanities have presented a statement on the Ebola epidemic today.

16 Oct 2014

Blend of three monoclonal antibodies can protect monkeys against Ebola virus, says UTMB researcher

A leading U.S. Ebola researcher from the University of Texas Medical Branch at Galveston has gone on record stating that a blend of three monoclonal antibodies can completely protect monkeys against a lethal dose of Ebola virus up to 5 days after infection, at a time when the disease is severe.

30 Aug 2014

Researchers plan to develop vaccine into a type of antibody serum therapy

By many estimates, an Ebola vaccine could be available in humans as early as next year. But will it be the right one? There are a number of vaccines in development and each is in a race to prove that it is most effective, safe and that it will protect the largest number of people.

7 Aug 2014

EcoHealth Alliance examines the origins of Ebola virus outbreaks

EcoHealth Alliance, a nonprofit organization that focuses on conservation and global public health issues, published a comprehensive review today examining the current state of knowledge of the deadly Ebola and Marburg virus.

21 Apr 2014

NIH awards $28M grant to establish new center for excellence to find treatment for Ebola virus

The National Institutes of Health has awarded a five-year, $28 million grant to establish a new center for excellence to find an antibody "cocktail" to fight two types of viruses that cause severe hemorrhagic fever, including the deadly Ebola virus. The project involves researchers from 15 institutions, including Kartik Chandran, Ph.D., and Jonathan Lai, Ph.D., at Albert Einstein College of Medicine of Yeshiva University. Einstein will receive approximately $4 million of the total grant.

21 Mar 2014

Marburg Virus News and Research

Further Reading

Antiviral agent protects rhesus monkeys from deadly Ebola virus

Health Partnership Scheme funds project dedicated to viral haemorrhagic fever

Researchers develop chip-based instrument for reliable detection of Ebola virus

Harvard Medical School scientists reveal structure of vesicular stomatitis virus protein

TSRI-led study identifies new immune molecules that protect against Marburg virus

New study reveals key part of Ebola virus life cycle at higher resolution than ever before

Researchers show how human antibodies can neutralize Marburg virus

TSRI scientists show how to target weak spots of Marburg virus with future treatments

Researchers reveal how human immune system can fight against deadly Marburg virus

Study: Airport screening for disease often misses infected travellers, but can be improved

Experimental Ebola vaccine safe and immunogenic in African population

New study finds that it is possible to distinguish between different hemorrhagic fevers

Research findings could pave way for new treatments against filoviruses

Profectus BioSciences gets funding to develop VesiculoVax Zaire-Ebola virus vaccine

NIAID announces license agreement to develop dual-purpose candidate vaccines for rabies, Ebola

Statement on Ebola epidemic

Blend of three monoclonal antibodies can protect monkeys against Ebola virus, says UTMB researcher

Researchers plan to develop vaccine into a type of antibody serum therapy

EcoHealth Alliance examines the origins of Ebola virus outbreaks

NIH awards $28M grant to establish new center for excellence to find treatment for Ebola virus

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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