Mass Spectrometry News and Research

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Mass spectrometry is an analytical method used to identify different compounds based on the atomic sample constitution of the molecules and their charge state, which enables “blind” analysis of an unknown sample without any prior knowledge of its composition.

Salk researchers discover molecule that destroys key HIV protein

One of the many challenges in treating HIV is that the virus can lie dormant in cells, quietly evading immune detection until it suddenly roars to life without warning and begins replicating furiously.

1 Jun 2018

New technique provides more direct way to discern what microbes consume

A new technique devised by researchers from North Carolina State University and the University of Calgary provides a more in-depth look at the metabolism and physiology within microbial communities - the microscopic life such as bacteria, viruses and other tiny forms of life within our bodies and throughout nature.

31 May 2018

Researchers take important step toward finding protein biomarkers during cancer surgery

Isabelle Fournier and her team are out to change surgical oncology. "Better surgery is associated with better prognosis and higher survival," said Fournier, a professor at the University of Lille and co-director of a proteomics center of INSERM, the French national institute of health.

24 May 2018

New study unravels secrets of HIV's persistence

Thanks to advances in the development of anti-retroviral therapy (ART), patients with HIV are living longer than ever before. And yet, even in patients on very effective, long-term ART, HIV persists, requiring patients to take antiviral medication life-long.

23 May 2018

Developing a High Throughput Mass Spectrometry Platform for Drug Discovery

Prof. Jonathan Wingfield, AstraZeneca, describes the collaboration with Labcyte and Waters to develop a high throughput mass spectrometry platform.

From Pittcon 18 May 2018

Old drug offers new hope for treatment of MND

An international study led by biochemists at the University of Liverpool has shown that the drug-molecule ebselen can correct many of the toxic characteristics of a protein that causes some cases of hereditary motor neurone disease (MND).

17 May 2018

Volatile biomarkers could help detect acute and asymptomatic malaria infections

Malaria is still a deadly disease in tropical and subtropical regions. Every year the disease infects more than 200 million people worldwide, claiming several hundred thousand victims.

15 May 2018

Scientists uncover new target for MRSA

Researchers at Michigan State University have identified why methicillin-resistant Staphylococcus aureus or MRSA is so resilient, a finding that could pave the way for potential new treatments.

15 May 2018

New study aims to turn MRSA’s strength against it

Antibiotic-resistant infections cause more than 30,000 deaths annually in the U.S. alone. The majority of those are caused by methicillin-resistant Staphylococcus aureus, more commonly known as MRSA, which can turn routine medical operations into near-death battles.

15 May 2018

Protein researchers identify several new potential targets for cancer

In a new study based on mouse cells internationally leading protein researchers have identified several new potential targets using state-of-the-art technology, many of which could be employed for future treatment of different types of cancers and diseases.

14 May 2018

New tool provides high accuracy and precision in analyzing disease and drug effects

A new protein analysis tool developed at the University at Buffalo could vastly increase the speed and precision with which disease and drug effects are analyzed.

11 May 2018

New chemical trap catches trace glycoproteins, shows promise for targeted cancer treatments

Cancer drops sparse chemical hints of its presence early on, but unfortunately, many of them are in a class of biochemicals that could not be detected thoroughly, until now.

8 May 2018

Study identifies new biomarker for early lung cancer diagnosis

High levels of cytoskeleton-associated protein 4 (CKAP4) have been identified in the blood of patients with lung cancer.

8 May 2018

Placental hormone level rises during pregnancy and reaches peak as fetuses approach full term

Just as a runner steadily builds up endurance in order to peak at just the right time, the placenta carefully calibrates how much of the hormone allopregnanolone it produces during pregnancy.

7 May 2018

COstatus monitors could offer way to directly measure cardiac output among neonates

Clinicians caring for vulnerable babies in the neonatal intensive care unit need to closely monitor their vital signs, but precisely gauging the function of their tiny hearts has remained elusive.

7 May 2018

Targeted 'click-to-release' chemotherapy leads to potent antitumor activity in mice

Antibody Drug Conjugates are relatively new anti-cancer drugs. They consist of an antibody to which a cell-killing molecule (chemotherapy) is attached. Antibodies can recognize and bind to certain receptors (the 'hands' on the outside of a cell) in a very targeted way.

4 May 2018

Charles River Laboratories Expands Services for Early Discovery Screening

Charles River Laboratories International, Inc. recently announced the expansion of its service capabilities in early discovery screening.

4 May 2018

Researchers find novel approach for in vivo real-time monitoring of metabolites

Real-time monitoring of the dynamics of endogenous molecules in organisms is an important aspect in the study of diseases.

2 May 2018

Study identifies unique bacterial behavioral response to certain antibiotics

In a new study published in the Journal of Biological Chemistry, researchers from the University of Notre Dame and the University of Illinois at Urbana-Champaign have found that the bacterium Pseudomonas aeruginosa, a pathogen that causes pneumonia, sepsis and other infections, communicates distress signals within a group of bacteria in response to certain antibiotics.

27 Apr 2018

Researchers develop new method for early and accurate breast cancer screening

A new method for early and accurate breast cancer screening has been developed by researchers at Ben-Gurion University of the Negev and Soroka University Medical Center, using commercially available technology.

25 Apr 2018