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Mastectomy is surgery to remove the breast (or as much of the breast tissue as possible).
Discovery could lead to major breakthrough in breast and ovarian cancer

Discovery could lead to major breakthrough in breast and ovarian cancer

Cancer researchers at Queen's University Belfast have made a breakthrough which could signal new treatments for women at high risk of breast and ovarian cancer. [More]
Faster DNA sequencing techniques likely to improve care for breast cancer patients

Faster DNA sequencing techniques likely to improve care for breast cancer patients

Faster and cheaper DNA sequencing techniques will likely improve care for patients with breast cancer but also create challenges for clinicians as they counsel patients on their treatment options. [More]
Faster DNA sequencing techniques more likely to improve care for patients with breast cancer

Faster DNA sequencing techniques more likely to improve care for patients with breast cancer

Faster and cheaper DNA sequencing techniques will likely improve care for patients with breast cancer but also create challenges for clinicians as they counsel patients on their treatment options. [More]
Synta Pharmaceuticals' Hsp90 inhibitor ganetespib selected for study in I-SPY 2 TRIAL

Synta Pharmaceuticals' Hsp90 inhibitor ganetespib selected for study in I-SPY 2 TRIAL

Synta Pharmaceuticals Corp. and QuantumLeap Healthcare Collaborative today announced that Synta's lead drug candidate, the Hsp90 inhibitor ganetespib, has been selected for study in the I-SPY 2 TRIAL (Investigation of Serial Studies to Predict Your Therapeutic Response with Imaging And moLecular Analysis 2). [More]

Chemotherapy induces long-lasting epigenetic changes in survivors' blood cells

Many breast cancer survivors experience fatigue and other debilitating symptoms that persist months to years after their course of treatment has ended. [More]

Study: Women with BRCA1 mutations should have preventive ovarian surgery by age 35

The findings of a large international prospective study published in the Journal of Clinical Oncology suggest for the first time that women with BRCA1 mutations should have preventive ovarian surgery (prophylactic oophorectomy) by age 35, as waiting until a later age appears to increase the risk of ovarian cancer before or at the time of the preventive surgery. [More]
Majority of women who undergo mastectomy go on to get breast reconstruction

Majority of women who undergo mastectomy go on to get breast reconstruction

A new study finds that the majority of women who undergo mastectomy for breast cancer go on to get breast reconstruction, a practice that has increased dramatically over time. [More]

Study shows benefit of double mastectomy in women with BRCA-related breast cancer

Women with BRCA-related breast cancer who have a double mastectomy are nearly 50 per cent less likely to die of breast cancer within 20 years of diagnosis compared to women who have a single mastectomy, according to a new study led by Women's College Hospital's Kelly Metcalfe. [More]

ASTRO, SSO guideline focuses on reducing ipsilateral breast tumor recurrence in stages I, II breast cancer

The American Society for Radiation Oncology (ASTRO) and the Society of Surgical Oncology (SSO) are pleased to announce the publication of the consensus guideline on margins for breast-conserving surgery with whole-breast irradiation in stages I and II invasive breast cancer. [More]

Poll shows only 35% of respondents likely to seek aggressive treatment to cancer

A national poll from the University of Utah's Huntsman Cancer Institute shows 34 percent of respondents would not seek genetic testing to predict their likelihood of developing a hereditary cancer - even if the cost of the testing was not an issue. [More]

EBRT provides higher breast preservation rate in women with invasive breast cancer

Standard external beam radiation therapy (EBRT) provided a higher breast preservation rate than brachytherapy in women age 66 and older with invasive breast cancer, according to a study published in the February 1, 2014 print edition of the International Journal of Radiation Oncology ● Biology ● Physics (Red Journal), the official scientific journal of the American Society for Radiation Oncology (ASTRO). [More]
Moderate radiation doses can kill premalignant cells and prevent second breast cancers

Moderate radiation doses can kill premalignant cells and prevent second breast cancers

​Survivors of breast cancer have a one in six chance of developing breast cancer in the other breast. But a study conducted in mice suggests that survivors can dramatically reduce that risk through treatment with moderate doses of radiation to the unaffected breast at the same time that they receive radiation therapy to their affected breast. [More]
Lifestyle changes and screening tools prove to reduce cancer risk, says doctor

Lifestyle changes and screening tools prove to reduce cancer risk, says doctor

President Nixon funded research to wage a war on cancer, a long battle that we're still fighting today. While the last 40 years haven't brought us a cure, we have made some meaningful progress in developing tools and knowledge to take a bite out of our cancer risk. [More]

Cosmetic results after "lumpectomy" differ for African-American versus Caucasian women

As perceived by both patients and doctors, the cosmetic results after "lumpectomy" for breast cancer differ for African-American versus Caucasian women, suggests a pilot study in the Plastic and Reconstructive Surgery-Global Open-, the official open-access medical journal of the American Society of Plastic Surgeons (ASPS). [More]
Innovative therapy offers new hope to breast cancer patients

Innovative therapy offers new hope to breast cancer patients

​A novel breast-cancer therapy that partially reverses the cancerous state in cultured breast tumor cells and prevents cancer development in mice, could one day provide a new way to treat early stages of the disease without resorting to surgery, chemotherapy or radiation, a multi-institutional team led by researchers from the Wyss Institute of Biologically Inspired Engineering at Harvard University reported January 1 in Science Translational Medicine. [More]
Younger women with breast cancer less likely to receive radiotherapy after BCS

Younger women with breast cancer less likely to receive radiotherapy after BCS

Radiotherapy after breast conserving surgery has been shown to reduce the risk of breast cancer recurrence. However, although younger women tend to have more aggressive tumors and have higher risks of recurrence than older BC patients, they are less likely to receive RT after BCS, according to a study published December 24 in the Journal of the National Cancer Institute. Although treatment patterns among older BC patients have been well-studied, factors affecting non-compliance among younger women are not well-known. [More]

Scientists back ovarian cancer preventative surgery to improve survival

A study by Manchester scientists backs preventative surgery to improve survival for women who are at greater risk of getting ovarian cancer and suggests it appears helpful for women at risk of getting breast cancer because of genetic faults. [More]
Over-use of staging procedures more prevalent in younger, early-stage breast cancer patients

Over-use of staging procedures more prevalent in younger, early-stage breast cancer patients

More than one third of younger, early stage breast cancer patients undergo unnecessary imaging procedures - including position emission tomography (PET), computed tomography (CT), nuclear medicine bone scans (NMBS) and tumor markers (TM) -- at the time of staging and diagnosis, according to research from The University of Texas MD Anderson Cancer Center. [More]
New drug combination therapy effective for patients with HER2-positive breast cancer

New drug combination therapy effective for patients with HER2-positive breast cancer

Combining the chemotherapy drugs docetaxel and carboplatin with the HER2-targeted therapy trastuzumab was identified to be an ideal postsurgery treatment option for patients with HER2-positive breast cancer, regardless of tumor size and whether or not disease has spread to the lymph nodes, according to results from the BETH study presented here at the 2013 San Antonio Breast Cancer Symposium, held Dec. 10-14. [More]
Smoking and obesity increase odds of early breast implant loss

Smoking and obesity increase odds of early breast implant loss

New research findings published in the December issue of the Journal of the American College of Surgeons confirm that factors such as smoking and obesity increase the odds of early implant loss in women who undergo mastectomy and immediate breast reconstruction with implants. Additionally, the study authors propose a unique risk-scoring tool that allows surgeons to better counsel patients preoperatively about their predicted risk for complications. [More]