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Findings explain molecular mechanisms underlying microvascular disease in diabetes patients

Patients with diabetes are at increased risk of microvascular complications, which develop when the body's small blood vessels become diseased. One of the most common problems results when wounds fail to heal properly, which can lead to ulcers, chronic infections, and in the most serious cases, limb amputations.

5 Feb 2014

AADI receives grant from Tufts Health Plan Foundation to focus on healthy aging for older adults 60+

The Asian American Diabetes Initiative (AADI) at Joslin Diabetes Center has received a $70,089 grant from Tufts Health Plan Foundation to fund Healthy Living for All Seasons, which offers elderly Asians with, or at risk for, diabetes the opportunity to take part in educational workshops and seminars focusing on exercise, improved diet, and the prevention of diabetes complications.

4 Feb 2014

Scientists use SWI to study changes in brains of college-level ice hockey players with concussion

Using susceptibility-weighted imaging (SWI), researchers have identified microstructural changes in the brains of male and female college-level ice hockey players that could be due to concussive or subconcussive trauma.

4 Feb 2014

New super-resolution microscopy method could spot dozens of distinct types of biomolecules

A new microscopy method could enable scientists to generate snapshots of dozens of different biomolecules at once in a single human cell, a team from the Wyss Institute of Biologically Inspired Engineering at Harvard University reported Sunday in Nature Methods.

4 Feb 2014

Digital mammography screening with new photon-counting technique offers high diagnostic performance

Digital mammography screening with new photon-counting technique offers high diagnostic performance, according to a study published online in the journal Radiology.

4 Feb 2014

Children who received radiation as part of treatment may have lower long-term survival rates, says study

The first comprehensive, large-scale cohort study of the long-term survival of children treated for low-grade gliomas, the most common pediatric brain tumor, finds that almost 90 percent are alive 20 years later and that few die from the tumor as adults.

4 Feb 2014

Researchers develop cardiac tissue from human stem cells to find cures for heart diseases

When it comes to finding cures for heart disease, scientists at Icahn School of Medicine at Mount Sinai are working to their own beat. They may have developed a tissue model for the human heart that can bridge the gap between animal models and human clinical trial patients.

4 Feb 2014

IDH1 gene mutation determines best treatment for malignant astrocytomas

Astrocytomas are the most common malignant brain tumors. While most patients' tumors prove to be quite aggressive, outcomes overall can vary widely, with some patients surviving for many years.

4 Feb 2014

Parents of children with disabilities more likely to suffer from chronic health conditions

A University of Limerick study has found that parents of children with learning or developmental disabilities have an increased risk of depression and are more likely to suffer from chronic health conditions. The figures showed that 15% of parents of children with disabilities were classified as depressed and unfortunately less than half of them reported being treated for depression.

3 Feb 2014

Researchers identify protein critical to hematopoietic stem cell function, blood formation

Researchers at the University of California, San Diego School of Medicine have identified a protein critical to hematopoietic stem cell function and blood formation. The finding has potential as a new target for treating leukemia because cancer stem cells rely upon the same protein to regulate and sustain their growth.

3 Feb 2014

Treating peanut allergy with oral immunotherapy changes DNA of immune cells

Treating a peanut allergy with oral immunotherapy changes the DNA of the patient's immune cells, according to a new study from the Stanford University School of Medicine and Lucile Packard Children's Hospital Stanford. The DNA change could serve as the basis for a simple blood test to monitor the long-term effectiveness of the allergy therapy.

31 Jan 2014

Comparison of cognitive tests shows SDMT effective in differentiating employment status in MS individuals

Researchers at Kessler Foundation have studied the measurement tools used in multiple sclerosis for their effectiveness in predicting employment status. They compared the Expanded Disability Status Scale (EDSS), the Multiple Sclerosis Functional Composite (MSFC), the Paced Auditory Serial Addition Task (PASAT), and the Symbol Digit Modalities Test (SDMT), and found the SDMT effective in differentiating employed from unemployed individuals.

31 Jan 2014

Study describes new tack in treatment of lung adenocarcinomas

The most common genetic subtype of lung cancer, which has long defied treatment with targeted therapies, has had its growth halted by a combination of two already-in-use drugs in laboratory and animal studies, setting the stage for clinical trials of the drugs in patients, researchers at Dana-Farber Cancer Institute and other scientists report in a new study.

31 Jan 2014

Retrieval practice can improve memory in individuals with severe TBI

Kessler Foundation researchers have shown that retrieval practice can improve memory in individuals with severe traumatic brain injury (TBI). "Retrieval Practice Improves Memory in Survivors of Severe Traumatic Brain Injury," was published as a brief report in the current issue of Archives of Physical Medicine & Rehabilitation Volume 95, Issue 2 (390-396) February 2014.

31 Jan 2014

Vanda Pharmaceuticals announces FDA approval of HETLIOZ for Non-24 treatment

Vanda Pharmaceuticals Inc. today announced that the U.S. Food and Drug Administration has approved HETLIOZ (tasimelteon) 20mg capsules for the treatment of Non-24-Hour Sleep-Wake Disorder (Non-24). HETLIOZ is the first FDA approved medication for Non-24.

31 Jan 2014

Boehringer Ingelheim, DCRI partner to uncover insights into idiopathic pulmonary fibrosis

Boehringer Ingelheim Pharmaceuticals, Inc. and Duke Clinical Research Institute have formed a unique collaborative relationship to uncover insights into idiopathic pulmonary fibrosis (IPF), a progressive and fatal lung disease.

31 Jan 2014

Report highlights recommendations to advance safety of childbirth in Indonesia

Indonesia is a fast-rising economic power that has made significant progress toward key development goals including reducing child mortality. But for reasons outlined in a National Academy of Sciences report by U.S. and Indonesian experts, the nation's estimated rates of maternal and neonatal mortality remain tragically high.

31 Jan 2014

More than 1/3 of women experience hot flashes for 10 years after menopause

A team of researchers from the Perelman School of Medicine at the University of Pennsylvania has found that moderate to severe hot flashes continue, on average, for nearly five years after menopause, and more than a third of women experience moderate/severe hot flashes for 10 years or more after menopause.

31 Jan 2014

Longer looks: Doctor guilt; an abortion provider's hidden record

Okay, I know I'm a health writer, but I really don't like going to the doctor. Part of it is an unshakeable, irrational certainty that they will find something horribly wrong with me that I'd rather not know about, and part of it is a rational certainty that they will find something mildly wrong with me that is my fault and chastise me for it-;drinking too much, not exercising enough, whatever. One should be able to talk to one's doctor about these things-;the aspects of one's lifestyle that maybe aren't so great. ... But in 2009, a study by researchers at the University of California, San Diego found that half of the patients surveyed had experienced shame as a result of something a doctor said to them.

31 Jan 2014

Researchers identify components of C. diff bacteria that can be used to develop better treatment

Rhode Island Hospital researchers have identified components in Clostridium difficile (C. diff) that may lead to new diagnostic tools, and ultimately more timely and effective treatment for this often fatal infection. C. diff is a spore-forming bacterium that causes severe diarrhea and is responsible for 14,000 deaths annually in the U.S. The study is published online in advance of print in the Journal of Molecular Diagnostics.

31 Jan 2014

Medical School News and Research

Findings explain molecular mechanisms underlying microvascular disease in diabetes patients

AADI receives grant from Tufts Health Plan Foundation to focus on healthy aging for older adults 60+

Scientists use SWI to study changes in brains of college-level ice hockey players with concussion

New super-resolution microscopy method could spot dozens of distinct types of biomolecules

Digital mammography screening with new photon-counting technique offers high diagnostic performance

Children who received radiation as part of treatment may have lower long-term survival rates, says study

Researchers develop cardiac tissue from human stem cells to find cures for heart diseases

IDH1 gene mutation determines best treatment for malignant astrocytomas

Parents of children with disabilities more likely to suffer from chronic health conditions

Researchers identify protein critical to hematopoietic stem cell function, blood formation

Treating peanut allergy with oral immunotherapy changes DNA of immune cells

Comparison of cognitive tests shows SDMT effective in differentiating employment status in MS individuals

Study describes new tack in treatment of lung adenocarcinomas

Retrieval practice can improve memory in individuals with severe TBI

Vanda Pharmaceuticals announces FDA approval of HETLIOZ for Non-24 treatment

Boehringer Ingelheim, DCRI partner to uncover insights into idiopathic pulmonary fibrosis

Report highlights recommendations to advance safety of childbirth in Indonesia

More than 1/3 of women experience hot flashes for 10 years after menopause

Longer looks: Doctor guilt; an abortion provider's hidden record

Researchers identify components of C. diff bacteria that can be used to develop better treatment

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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