Medicinal Chemistry News and Research RSS Feed - Medicinal Chemistry News and Research

Tiny molecular scaffolding could be key to fight against antibiotic resistance

Tiny molecular scaffolding could be key to fight against antibiotic resistance

Tiny molecular scaffolding that joins molecules together could be the key to our battle against antibiotic resistance. Research published in Bioorganic & Medicinal Chemistry Letters shows that carbon nanodot scaffolding assembled with small molecules called polyamines can kill some dangerous drug-resistant bacteria, including Acinetobacter baumanii and Klebsiella pneumonia. [More]
New experimental antibiotic can help combat MRSA infections

New experimental antibiotic can help combat MRSA infections

A new experimental antibiotic developed by a team of scientists at Rutgers University successfully treats the deadly MRSA infection and restores the efficacy of a commonly prescribed antibiotic that has become ineffective against MRSA. [More]
Researchers identify promising new compound for targeting triple-negative breast cancer

Researchers identify promising new compound for targeting triple-negative breast cancer

Researchers at the University of Michigan have identified a promising new compound for targeting one of the most aggressive types of breast cancer. [More]
Researchers discover new potential treatment target for liver cancer

Researchers discover new potential treatment target for liver cancer

Researchers at the University of Eastern Finland and Eberhard Karls Universität Tübingen have discovered a new molecular mechanism that can be used to inhibit the growth of hepatocellular carcinoma, which is the most common liver cancer. [More]
Chemical compound eCF506 may be highly effective at blocking growth of breast cancer cells

Chemical compound eCF506 may be highly effective at blocking growth of breast cancer cells

A drug for breast cancer that is more effective than existing medicines may be a step closer thanks to new research. [More]
AKR1C3 enzyme could be promising therapeutic target for managing CRPC, AML

AKR1C3 enzyme could be promising therapeutic target for managing CRPC, AML

Prostate cancer is the second leading cause of mortality among American men with the highest incidence rate of all cancers reported in the U.S. Male sex hormones testosterone (T) and 5α-dihydrotestosterone (5α-DHT) promote prostate cancer progression. [More]
New version of obesity drug could help people reduce weight without experiencing anxiety, depression

New version of obesity drug could help people reduce weight without experiencing anxiety, depression

A new version of an obesity drug that caused serious psychiatric side effects could help people lose pounds without experiencing the anxiety, depression and suicidal thoughts previously associated with it. The research, published in Bioorganic and Medicinal Chemistry, shows that the new version of the drug can still work without reaching the brain in rats, avoiding the side effects. [More]
TSRI chemists develop new method to achieve chemical reaction in pharmaceutical industry

TSRI chemists develop new method to achieve chemical reaction in pharmaceutical industry

Scientists at The Scripps Research Institute have found a new and better way to achieve a chemical reaction that is used widely in the pharmaceutical as well as flavor and fragrance industries. [More]
U of S-led researchers develop novel class of compounds for effective cancer treatment

U of S-led researchers develop novel class of compounds for effective cancer treatment

A novel class of compounds developed by a University of Saskatchewan-led research team could yield more effective and less toxic chemotherapy drugs to treat cancer. [More]
France-based pharmaceutical company deploys Porvair Sciences' Ultravap Mistral in medicinal chemistry department

France-based pharmaceutical company deploys Porvair Sciences' Ultravap Mistral in medicinal chemistry department

Porvair Sciences reports that a major Pharmaceutical company based in France has integrated its Ultravap Mistral blowdown evaporation system with a Hamilton Star robotic liquid handling system to enhance new drug candidate processing in its medicinal chemistry department. [More]
WSU researcher explores new drugs to treat neurological disorders linked to autophagic dysfunction

WSU researcher explores new drugs to treat neurological disorders linked to autophagic dysfunction

Repairing the brain's "house-cleaning function," which could help people with Alzheimer's, Parkinson's, amyotrophic lateral sclerosis (ALS) and 100 other diseases, is the focus of recently funded research at Washington State University. [More]
Scientists synthesize novel selenohydantoins with anticancer and antioxidant activity

Scientists synthesize novel selenohydantoins with anticancer and antioxidant activity

A group of scientists from Moscow universities led by Yan Ivanenkov, the head of Laboratory of Medical Chemistry and Bioinformatics in MIPT, has succeeded in synthesizing a set of novel selenohydantoins with anticancer and antioxidant activity. [More]
Researchers aim to design a better male contraceptive pill

Researchers aim to design a better male contraceptive pill

Women can choose from a wide selection of birth control methods, including numerous oral contraceptives, but there's never been an analogous pill for men. That's not for lack of trying: For many years, scientists have attempted to formulate a male pill. Finally, a group of researchers has taken a step toward that goal by tweaking some experimental compounds that show promise. [More]
Scientists discover novel drug candidate to treat breast cancer, lung cancer and melanoma

Scientists discover novel drug candidate to treat breast cancer, lung cancer and melanoma

Using a new approach, scientists at The Scripps Research Institute and collaborating institutions have discovered a novel drug candidate that could be used to treat certain types of breast cancer, lung cancer and melanoma. [More]
New vaccine delays effects of nicotine within first 10 minutes after injection

New vaccine delays effects of nicotine within first 10 minutes after injection

Many people who smoke want to quit, but the urge to light up is often irresistible. An effective vaccine to help people kick the habit once and for all has been elusive. But now, scientists report in ACS' Journal of Medicinal Chemistry a new vaccine design that could help achieve this goal. [More]
Advances in medicinal chemistry evaporators: an interview with Alison Wake, Genevac

Advances in medicinal chemistry evaporators: an interview with Alison Wake, Genevac

The Genevac Series 1 System, which was launched in the mid 1990s, had no programming as such. It was a very basic system – it had basic vacuum control and a timer of sorts. It was very similar to the current myVac evaporator system we use for molecular biology and biological applications. [More]
New screening technique to test drug compounds used in Ewing sarcoma treatment

New screening technique to test drug compounds used in Ewing sarcoma treatment

In Ewing sarcoma, cancer cells' DNA is unwound abnormally from a condensed, compact state. Once sections of genetic code are open, key genes are turned on to help direct aggressive and cancerous cell growth. [More]
Anti-biofilm compounds show promise against drug-resistant bacteria associated with hospital-acquired infections

Anti-biofilm compounds show promise against drug-resistant bacteria associated with hospital-acquired infections

Researchers at the University of Michigan Life Sciences Institute and School of Public Health have discovered a new class of anti-biofilm compounds derived from marine microorganisms that show promise against a drug-resistant bacterium commonly associated with hospital-acquired infections. [More]
Leeds scientists to start computer drug research to find cure for Ebola virus

Leeds scientists to start computer drug research to find cure for Ebola virus

Scientists at the University of Leeds will run the equivalent of password cracking software to find the chemical keys to defeating the Ebola virus. [More]
Flexible Solution for High Throughput Evaporation

Flexible Solution for High Throughput Evaporation

Genevac Series 3 HT evaporators provide an ideal solution for evaporation bottlenecks in high throughput medicinal chemistry, natural product and production laboratories that generate large numbers of samples for processing. [More]
Advertisement
Advertisement