Metabolic Disorders News and Research

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Study demonstrates how the transcription factor C/EBPβ can positively influence fat storage

The chronic nutritional and metabolic disease of obesity is characterized by an excessive increase in body fat and its accumulation in tissues.

20 May 2022

Molecular pathway allows cells to sense when their lipid supplies become depleted

UT Southwestern researchers have discovered a molecular pathway that allows cells to sense when their lipid supplies become depleted, prompting a flurry of activity that prevents starvation.

18 May 2022

Breastfeeding associated with improved maternal mental health outcomes

Scientists from the University of Massachusetts, USA, have recently found that breastfeeding is associated with improved maternal mental health overall.

10 May 2022

Benefits of endurance exercise in primary mitochondrial disease depend on the underlying mutation

Mitochondria serve as the main source of energy production in our cells, and endurance exercise is generally known to improve the function of mitochondria.

4 May 2022

Reducing daily sedentary time can help prevent diabetes and cardiovascular diseases

A new study suggests that reducing daily sedentary time can have a positive effect on the risk factors of lifestyle diseases already in three months. Spending just one hour less sitting daily and increasing light physical activity can help in the prevention of these diseases.

4 May 2022

Study investigates intestinal ischemia in COVID-19 patients

A team of Italian scientists has presented case reports of five coronavirus disease 2019 (COVID-19) patients undergoing emergency surgery for intestinal ischemia.

28 Apr 2022

Scientists investigate how gut bacteria directly control the activity of specific neurons

Gut microbiota by-products circulate in the bloodstream, regulating host physiological processes including immunity, metabolism and brain functions.

15 Apr 2022

Discovery of key regulator of body weight could lead to new treatments for metabolic disorders

Yale scientists uncover key regulator of body weight. Yale scientists have discovered that a protein known as augmentor-alpha regulates body weight in mice, an insight that could lead to new treatments for metabolic disorders.

11 Apr 2022

Multi-mineral supplement could help reduce downstream consequences of fatty liver disease

Results from a preclinical study add new evidence that a multi-mineral dietary supplement known as Aquamin could be a simple and effective way to reduce the long-term health consequences of non-alcoholic fatty liver disease.

3 Apr 2022

Prevalence of organ impairment in Long COVID patients 6 and 12 months after initial symptoms

Researchers assessed the prevalence of organ impairment in long COVID six months and a year post-COVID-19 at London and Oxford.

24 Mar 2022

Breathlessness and fatigue most common in self reported long-COVID

A new systematic review and meta-analysis posted to the medRxiv* preprint server has focussed on investigating the respiratory outcomes and functional recovery of patients eight weeks post-hospitalization with COVID-19 disease.

24 Mar 2022

Powerful tool to monitor membrane proteins trafficking for drug discovery

Inside your body on the surface of cell membranes, a metaphorical communication and traffic network is underway as hormones - or chemical messengers - bind to cell membrane receptors to fine tune how the cell behaves.

22 Mar 2022

New inhibitor shows promise in fighting obesity and preventing heart disease

An interdisciplinary research team at The University of Texas at San Antonio has successfully developed an innovative inhibitor that shows promise in fighting obesity and potentially preventing heart disease.

4 Mar 2022

Research shows intergenerational effects of preconception opioids in male offspring rats

New research from scientists at Cummings School of Veterinary Medicine at Tufts University suggests opioid use before pregnancy-; even if not used during pregnancy itself-; could result in a higher likelihood that a mother's male offspring will develop type 2 diabetes and metabolic syndrome, conditions that increase the risk of heart disease and stroke.

28 Feb 2022

Novel mechanism that connects circadian rhythm and muscle repair discovered

Northwestern Medicine investigators have discovered a novel mechanism that connects circadian rhythm-controlled cellular metabolism and regeneration with muscle repair after injury, according to recent findings published in the journal Genes and Development.

28 Feb 2022

Study provides a promising new avenue for development of anti-obesity treatments

An anti-tumor drug promotes weight loss in mice at low doses by activating a natural hunger-suppressing pathway, according to a new study publishing February 24th in the open-access journal PLOS Biology by Jiang Wei Wu and colleagues at Northwest A&F University in Shaanxi, China.

24 Feb 2022

New therapeutic approach offers hope to treat obesity and related metabolic disorders

Scientists at Nanyang Technological University, Singapore (NTU Singapore) have developed a new therapeutic approach to obesity and related metabolic disorders that in laboratory experiments demonstrated a significant reduction in body fat, body weight, and improvement in the blood markers that accompany these disorders.

25 Jan 2022

Oral supplement appears to promote muscle endurance and mitochondrial health in humans

An oral supplement intended to stimulate a natural body process appears to promote muscle endurance and mitochondrial health in humans.

20 Jan 2022

Researchers receive CZI grant to support Asian Immune Diversity Atlas project

A team of researchers, led by the Agency for Science, Technology and Research's Genome Institute of Singapore (GIS), was awarded the prestigious Chan Zuckerberg Initiative Ancestry Network Grant in support of their Asian Immune Diversity Atlas (AIDA) project.

18 Dec 2021

Long-term exposure to air pollution linked to metabolic-associated fatty liver disease

Metabolic-associated fatty liver disease (MAFLD) is a growing global health challenge and poses a substantial economic burden. A large-scale epidemiologic study in China has identified links between long-term exposure to ambient air pollution and MAFLD.

6 Dec 2021