Metabolic Disorders News and Research

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Research shows basophils are key players in lung development

Lungs are vital organs required for the uptake of oxygen in exchange for carbon dioxide. However, the enormous complexity of the respiratory organ is often underestimated and deserves a closer look: A broad range of specialized cells work closely together to ensure the proper functioning of the lung and provide the vital gas exchange.

12 Oct 2018

Low levels of cellular copper may make fat cells fatter

In studies of mouse cells, Johns Hopkins researchers have found that low levels of cellular copper appear to make fat cells fatter by altering how cells process their main metabolic fuels, such as fat and sugar.

11 Oct 2018

New pre-clinical research shows utility of mRNA platform to treat rare metabolic disorders

An mRNA platform that can express therapeutic levels of protein in liver tissue could be used to treat patients with rare metabolic disorders.

9 Oct 2018

New genome editing tool used to heal genetic disease

Parents of newborns may be familiar with the metabolic disorder phenylketonuria: in Switzerland, all newborn babies are screened for this genetic disease.

8 Oct 2018

Genentech announces Phase III study results of baloxavir marboxil in people at high risk of flu

Genentech, a member of the Roche Group, today announced that the Phase III CAPSTONE-2 study showed treatment with baloxavir marboxil significantly reduced the time to improvement of influenza symptoms versus placebo in people at high risk of serious complications from the flu, which includes adults 65 years of age or older, or those who have conditions such as asthma, chronic lung disease, morbid obesity, or heart disease.

4 Oct 2018

Vanteres announces new evidence demonstrating role of LPC-DHA in fetal brain development

Vanteres, an innovative biotech company leveraging its biomedical research expertise to develop actively transported lysophospholipids, announces new evidence that demonstrates the critical role of LPC-DHA in normal fetal and infant brain development.

24 Sep 2018

Alexion announces positive results from Phase 3 PREVENT study of Soliris in patients with NMOSD

Alexion Pharmaceuticals, Inc. today announced positive topline results from the Phase 3 PREVENT study of Soliris in patients with anti-aquaporin-4 auto antibody-positive neuromyelitis optica spectrum disorder.

24 Sep 2018

Blocking RNA-silencing protein in the liver prevents obesity and diabetes in mice

Obesity and its related ailments like type 2 diabetes and fatty liver disease pose a major global health burden, but researchers report in Nature Communications that blocking an RNA-silencing protein in the livers of mice keeps the animals from getting fat and diabetic conditions.

11 Sep 2018

Study: Health and longevity improves with increased fasting time

Increasing time between meals made male mice healthier overall and live longer compared to mice who ate more frequently, according to a new study published in the Sept. 6, 2018 issue of Cell Metabolism.

7 Sep 2018

Short telomeres could be independent risk factor for age-related functional decline

Elderly people with short chromosome caps, or telomeres, are more likely to have difficulty performing daily activities such as carrying groceries, climbing stairs and walking, finds a new study of more than 1,200 people from five European countries.

6 Sep 2018

Researchers make discovery about yeast metabolism that could help drug developers

Researchers at the Francis Crick Institute have developed machine learning algorithms that can predict the metabolism of yeast based on its protein content.

6 Sep 2018

CSIRO project seeks to clear the air over potentially life-saving noble gases

Australia’s national science agency, CSIRO, partnered with world leader in medical gases, Air Liquide Healthcare, to reveal how the noble gases’ interactions with proteins could one day be used to treat a variety of health issues.

4 Sep 2018

Cardio exercise and strength training have diverse effects on hormones

Every day a lot of people cycle to and from work or visit the gym to lift heavy weights. Regardless of the form of training they choose, almost everyone does it to improve their health. But we actually know surprisingly little about exactly how different forms of training affect our health.

24 Aug 2018

Nutrition in early life may play a role in development of subsequent metabolic disorders

The findings, which come from a Journal of Diabetes analysis of 11,515 men and 13,569 women in China, indicate that nutrition in early life may play a role in the development of subsequent metabolic disorders.

22 Aug 2018

Study reveals why individuals carrying identical gene mutations have varying disease severity

Researchers at the New York Genome Center and Columbia University have uncovered a molecular mechanism behind one of biology's long-standing mysteries: why individuals carrying identical gene mutations for a disease end up having varying severity or symptoms of the disease.

20 Aug 2018

Researchers discover new promising target point for cancer and diabetes therapies

If certain signaling cascades are misregulated, diseases like cancer, obesity and diabetes may occur. A mechanism recently discovered by scientists at the Leibniz-Forschungsinstitut für Molekulare Pharmakologie in Berlin and at the University of Geneva has a crucial influence on such signaling cascades and may be an important key for the future development of therapies against these diseases.

15 Aug 2018

Researchers report new way to map the inner workings of a living cell

Imaging tools like X-rays and MRI have revolutionized medicine by giving doctors a close up view of the brain and other vital organs in living, breathing people. Now, Columbia University researchers report a new way to zoom in at the tiniest scales to track changes within individual cells.

6 Aug 2018

IU researchers receive $1.5 million NIH grant to advance study on diabetes risks

A $1.5 million grant from the National Institutes of Health will advance work by Indiana University researchers that seeks to identify Americans at risk for diabetes and other metabolic disorders based on their exposure to trace minerals in the environment.

3 Aug 2018

Claudia Langenberg wins Helmholtz International Fellow Award

"Claudia Langenberg is known for her research on genetic causes of insulin resistance, type 2 diabetes and related metabolic disorders," explains Dr. Gabi Kastenmüller, acting head of the Institute of Bioinformatics and Systems Biology.

3 Aug 2018

Transgender individuals may be at higher risk for cardiovascular disease

Transgender individuals may be at higher risk for myocardial infarction and death due to cardiovascular disease, according to several studies.

3 Aug 2018

Metabolic Disorders News and Research

Research shows basophils are key players in lung development

Low levels of cellular copper may make fat cells fatter

New pre-clinical research shows utility of mRNA platform to treat rare metabolic disorders

New genome editing tool used to heal genetic disease

Genentech announces Phase III study results of baloxavir marboxil in people at high risk of flu

Vanteres announces new evidence demonstrating role of LPC-DHA in fetal brain development

Alexion announces positive results from Phase 3 PREVENT study of Soliris in patients with NMOSD

Blocking RNA-silencing protein in the liver prevents obesity and diabetes in mice

Study: Health and longevity improves with increased fasting time

Short telomeres could be independent risk factor for age-related functional decline

Researchers make discovery about yeast metabolism that could help drug developers

CSIRO project seeks to clear the air over potentially life-saving noble gases

Cardio exercise and strength training have diverse effects on hormones

Nutrition in early life may play a role in development of subsequent metabolic disorders

Study reveals why individuals carrying identical gene mutations have varying disease severity

Researchers discover new promising target point for cancer and diabetes therapies

Researchers report new way to map the inner workings of a living cell

IU researchers receive $1.5 million NIH grant to advance study on diabetes risks

Claudia Langenberg wins Helmholtz International Fellow Award

Transgender individuals may be at higher risk for cardiovascular disease

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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