Metabolic Disorders News and Research

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Diet-induced obesity synchronizes opposing liver fat metabolic processes in mice

Mice fed a fattening diet develop new liver circadian rhythms that impact the way fat is accumulated and simultaneously burned, according to a new study published in Cell by researchers in the Perelman School of Medicine at the University of Pennsylvania.

27 Jul 2018

Study reveals key role of actin cytoskeletal dynamics in supporting immune cell function

In order to move, a body needs a strong scaffold. This is not only true on a macroscopic level, where animals rely on skeletons to support their muscles.

26 Jul 2018

Researchers find compounds that may pave way for new drugs against diabetes, obesity

A new study reveals that several drugs for treating hematological cancers are less effective than expected in inhibiting a special enzyme.

26 Jul 2018

FAU and partners receive NIH research grant to shed light on sleep loss and metabolic disorders

A neuroscientist from Florida Atlantic University's Jupiter Life Science Initiative and collaborators from the University of Minnesota and Stowers Institute for Medical Research recently a received a four-year, $1.68 million R01 research grant from the National Institutes of Health's National Institute of General Medical Sciences for a project titled, "Understanding Complex Trait Architecture through Population Genomics."

17 Jul 2018

Animal studies reveal brain changes responsible for appetite effects of cannabis

New research on how cannabis use alters eating behavior could lead to treatments for appetite loss in chronic illness, according to experts at Washington State University.

17 Jul 2018

UCLA researchers uncover gene that controls equilibrium of bone and fat in bone marrow

In an unexpected discovery, UCLA researchers have found that a gene previously known to control human metabolism also controls the equilibrium of bone and fat in bone marrow as well as how an adult stem cell expresses its final cell type.

13 Jul 2018

Compounds found in green tea and red wine offer hope to treat inborn congenital metabolic diseases

A new Tel Aviv University study suggests there is hope of treating certain inborn congenital metabolic diseases -- a hope found in green tea and in red wine.

2 Jul 2018

Chemical compounds produced by gut bacteria could help spot early stages of liver disease

Chemical compounds produced by the bacteria in our gut could be used to spot the early stages of liver disease, according to new research.

25 Jun 2018

Cedars-Sinai launches new initiative to improve treatments for gastrointestinal, metabolic diseases

Cedars-Sinai has launched an initiative to accelerate the development of novel drugs, devices and therapies aimed at improving treatments for patients with gastrointestinal and metabolic diseases.

25 Jun 2018

Study: Inner nuclear envelope plays role in lipid metabolism

The cell nucleus is an organelle, in which the DNA of an organism is protected and duplicated. The nucleus of this organ-like structure in the cell plasma is surrounded by an outer and an inner nuclear envelope, which is penetrated by openings - so-called nuclear pores.

22 Jun 2018

Scientists develop novel computational framework to support personalized cancer treatment

Researchers at Columbia University Irving Medical Center have developed a highly innovative computational framework that can support personalized cancer treatment by matching individual tumors with the drugs or drug combinations that are most likely to kill them.

19 Jun 2018

Researchers find enzyme responsible for aircraft noise-related vascular damage

In a recent study, scientists at the Department of Cardiology at the University Medical Center of Johannes Gutenberg University Mainz have identified an enzyme responsible for aircraft-related vascular damage.

14 Jun 2018

Scientists discover protective mechanism against atherosclerosis

Atherosclerosis, the pathological narrowing of blood vessels, is the underlying cause for the majority of strokes and heart attacks, the major causes of mortality worldwide according to the WHO.

12 Jun 2018

Teens and young adults with type 1 diabetes often experience stigma

Michael Wright was your average high school student, juggling the responsibilities of school and friends while taking the first steps towards finding his first real job.

12 Jun 2018

Synthetic gene reveals potential therapeutic target for rare, inherited disease

DNA Repair is essential for a healthy organism. In every day of our lives, tens of thousands of damages occur in the genetic material of our cells. Hence, it is not surprising that a broad variety of repair mechanisms developed in the course of evolution that enables cells to quickly react and patch up the affected DNA strands.

11 Jun 2018

Microbiotica collaborates with Genentech to develop drugs for IBD

Microbiotica, a leading player in microbiome-based therapeutics spun out of the Wellcome Sanger Institute, today announced that it has entered into a multi-year strategic collaboration with Genentech, a member of the Roche Group, to discover, develop and commercialize biomarkers, targets and medicines for inflammatory bowel disease.

6 Jun 2018

Researchers reveal role NAD+ molecule in turning on genes that make fat cells

Glucose is the energy that fuels cells, and the body likes to store glucose for later use. But too much glucose can contribute to obesity, and scientists have long wanted to understand what happens within a cell to tip the balance.

1 Jun 2018

Reducing exposure to hormone interfering chemicals may mitigate obesity risk

Everyday products carry environmental chemicals that may be making us fat by interfering with our hormones, according to research presented in Barcelona at the European Society of Endocrinology annual meeting, ECE 2018.

21 May 2018

Scientists identify new potential target to combat acute myeloid leukemia

AML is not a single disease. It is a group of leukemias that develop in the bone marrow from progenitors of specialized blood cells, the so-called myeloid cells. Rapidly growing and dividing, these aberrant cells crowd the bone marrow and bloodstream, which can be fatal within weeks or months if the disease is left untreated.

18 May 2018

Raising Awareness of Childhood Dementia

The Dementia Strikes Children Too campaign aims to raise awareness of childhood dementia, drive for better clinical education of this group of diseases, and put in place the systems and tools for earlier diagnosis.