Metabolic Disorders News and Research

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Exposure to insecticides that mimic melatonin could put people at higher risk for diabetes

Synthetic chemicals commonly found in insecticides and garden products bind to the receptors that govern our biological clocks, University at Buffalo researchers have found.

19 Jan 2017

Workplace-based sleep health program can reduce injuries and disability in firefighters

Many firefighters suffer acute and chronic sleep deficiency and misalignment of their circadian rhythm (body clock) due to extended shifts and long work weeks.

12 Jan 2017

Vitamin D supplementation improves metabolic syndrome in mice

It is well known that a diet high in fat can trigger a metabolic syndrome, a group of symptoms that pose as risk factors for diabetes and heart disease.

22 Dec 2016

Wellcome Trust Sanger Institute establishes spin-out company, Microbiotica

Cambridge Innovation Capital plc, a Cambridge-based investor in technology and healthcare companies, and IP Group plc, the developer of intellectual property-based businesses, announce the creation of Microbiotica Ltd, a newly formed spin-out company from the UK’s Wellcome Trust Sanger Institute based at the Wellcome Genome Campus in Hinxton, Cambridge.

21 Dec 2016

Disturbances in the body’s carbon monoxide metabolism linked to circadian disruption

Chronobiologists from Charité - Universitätsmedizin Berlin have shown that the body's carbon monoxide metabolism is closely linked to the body's circadian (internal) clock.

7 Dec 2016

Small fat-burning molecule could help combat global epidemic of obesity

A small molecule could provide valuable help in combating the global epidemic of obesity.

6 Dec 2016

New global network to explore link between genes and environmental factors to tackle health challenges

A new global network linking leading research centres across the world has launched today to tackle some of the most pressing global health challenges of our time such as autism, cancer, diabetes and dementia.

1 Dec 2016

Promethera presents new preclinical NASH-Fibrosis data from HepaStem program at AASLD meeting

Promethera Biosciences SA, a world-leading cell therapy and regenerative medicine company targeting liver diseases, today announced the presentation of new preclinical NASH-Fibrosis data from its proprietary HepaStem program, demonstrating a beneficial effect of HepaStem in a nonalcoholic steatohepatitis (NASH) mouse model and confirming Hepastem’s unique and multifaceted mode of action.

15 Nov 2016

Repeated binge drinking during adolescence can affect brain functions of future offspring

Repeated binge drinking during adolescence can affect brain functions in future generations, potentially putting offspring at risk for such conditions as depression, anxiety, and metabolic disorders, a Loyola University Chicago Stritch School of Medicine study has found.

15 Nov 2016

New wearable medical device may reduce visceral fat, improve blood glucose in diabetes patients

Although effective for the treatment of diabetes, exercise is sometimes difficult for overweight or elderly people.

11 Nov 2016

Targeted precision medicine can eliminate cancer risk in patients with Type 2 diabetes

The links between Type 2 diabetes and cancer are complex: people suffering from diabetes mellitus essentially have a higher risk of developing cancer but, on top of that, some diabetes drugs are also suspected of increasing the risk in some cases.

8 Nov 2016

Scientists reveal molecular elements that bridge anxiety and metabolism

Metabolic and anxiety-related disorders both pose a significant healthcare burden, and are in the spotlight of contemporary research and therapeutic efforts. Although intuitively we assume that these two phenomena overlap, the link has not been proven scientifically.

5 Oct 2016

Study provides insights into how insulin resistance, diabetes begin

Does eating too much sugar cause type 2 diabetes? The answer may not be simple, but a study published Sept. 26 in the Journal of Clinical Investigation adds to growing research linking excessive sugar consumption -- specifically the sugar fructose -- to a rise in metabolic disease worldwide.

26 Sep 2016

Researchers identify mutant traits in mouse for many human disease genes

About one-third of all genes in the mammalian genome are essential for life. An international, multi-institutional research collaboration identified, for the first time, mutant traits in the mouse for 52 human disease genes, which significantly contributes to the understanding of the genetic bases for some human diseases, including cardiovascular defects, spina bifida, and metabolic disorders, among many others. The study was published this week in Nature.

19 Sep 2016

Scientists generate functional tissue-engineered liver from adult stem and progenitor cells

A research team led by investigators at The Saban Research Institute of Children's Hospital Los Angeles has generated functional human and mouse tissue-engineered liver from adult stem and progenitor cells.

31 Aug 2016

SAGA funding initiative aims to advance understanding of potential sex differences in Alzheimer's

The first-ever Alzheimer's Association Sex and Gender in Alzheimer's research grant awards will provide $2.2 million to nine projects to advance understanding of the disproportionate effect of Alzheimer's disease on women.

31 Aug 2016

Gene mutation linked to impulsive drunken behaviour shields bearers from obesity, insulin resistance

University of Helsinki researchers have previously demonstrated that a point mutation in a gene of serotonin 2B receptor can render the carrier prone to impulsive behaviour, particularly when drunk.

10 Aug 2016

Sophia Genetics reveals world’s most advanced collective artificial intelligence platform

Sophia Genetics, the global leader in Data-Driven Medicine, today unveiled SOPHiA, the world’s most advanced collective artificial intelligence (AI) for Data-Driven Medicine.

29 Jul 2016

Researchers test new approach to treat metabolic diseases without organ transplant

With a shortage of donor organs, Mayo Clinic is exploring therapeutic strategies for patients with debilitating liver diseases. Researchers are testing a new approach to correct metabolic disorders without a whole organ transplant. Their findings appear in Science Translational Medicine.

27 Jul 2016

Study explores rate of antipsychotic polypharmacy among patients discharged from psychiatric hospitals

In recent years, measures have been introduced to reduce the rate of "antipsychotic polypharmacy"—taking more than one antipsychotic drug—among patients with schizophrenia and other serious mental illnesses.

20 Jul 2016