Metabolic Profiling News and Research

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Discovery of early biomarkers paves way for new insight into Huntington's disease

Early warning signs of Huntington's disease have been uncovered in a sheep carrying the human HD mutation, leading the way for new insight into this devastating illness, a new study in Scientific Reports has found.

22 Feb 2017

NMR and metabolic phenotyping

In this interview, Dr Harmut Schafer introduces the work being done at the Phenome Center in Birmingham, on metabolic phenotyping using NMR.

From Bruker BioSpin - NMR, EPR and Imaging 31 Jan 2017

New test developed by Loughborough University may offer one-stop diagnosis for asthma

A new test which can diagnose asthma from a patient's saliva has been developed by Loughborough University.

16 Sep 2016

Researchers identify biomarkers to improve prognosis of CKD

Currently, there is no effective method to predict the prognosis of chronic kidney disease (CKD) patients.

27 Jul 2016

Tackling healthcare challenges in a changing world: an interview with Professor Jeremy Nicholson

As individuals and as populations our risks of getting diseases are determined partly genetically and partly from the environment that we live in. An important part of that environment that mediates between the outside world and the inside world of our bodies is the microbiome.

10 Jun 2016

A*STAR scientists pioneered a molecular connection between obesity and diabetes

Scientists from the Institute of Molecular and Cell Biology, a research institute under the Agency for Science, Technology and Research, have discovered that obese individuals lack a protein that is essential for regulating blood glucose levels, causing them to face higher risks of developing diabetes.

1 Jul 2014

Scientists explain how green tea may work to reduce risk of cancer

Green tea and its extracts have been widely touted as potential treatments for cancer, as well as several other diseases.

31 May 2014

Scientists step in with new way to determine drug safety without using animals

As some countries and companies roll out new rules to limit animal testing in pharmaceutical products designed for people, scientists are stepping in with a new way to test therapeutic drug candidates and determine drug safety and drug interactions — without using animals.

19 Mar 2014

Metabolic profiling of liver cells suggests new treatments for cirrhosis patients

In a new study that could help doctors extend the lives of patients awaiting liver transplants, a Rice University-led team of researchers examined the metabolic breakdown that takes place in liver cells during late-stage cirrhosis and found clues that suggest new treatments to delay liver failure.

5 Mar 2014

Meclizine drug has the potential to treat certain infectious diseases and cancer

Meclizine, an over-the-counter drug used for decades to treat nausea and motion sickness, has the potential for new uses to treat certain infectious diseases and some forms of cancer, according to Dr. Vishal M. Gohil, Texas A&M AgriLife Research biochemist.

31 Oct 2013

Research into 'personalised' medicine is being led by Greenwich team

Research into 'personalised' medicine is being led by a University of Greenwich team. Currently, many medicines which are prescribed to patients either do not work properly or have some significant side effects. The aim of personalised medicine, sometimes called 'precision' medicine, is to ensure that the most appropriate medicine is given to each patient and that the medicine is both effective and safe.

5 Sep 2013

Bruker introduces AVANCE-IVDr platform for NMR clinical research and screening

Bruker today announces a standardized nuclear magnetic resonance (NMR) spectroscopy platform for its clinical and diagnostics partners that enables cost-effective, high-performance NMR clinical screening and IVD-by-NMR discovery, development and validation of novel NMR assays.

24 Jul 2013

Urine tests could improve diagnosis of liver cancer

New data from two clinical trials presented today at the International Liver Congress- 2013 demonstrate substantial improvements in the detection of both hepatocellular carcinoma (HCC) and cholangiocarcinoma (CC) using diagnostic urine tests.

26 Apr 2013

SiDMAP announces publication of Isotopolome Wide Association Study in FASEB Journal

SiDMAP, LLC, a leading provider of metabolic profiling and biomarker development services to the pharmaceutical, academic, governmental, and biotechnology industries, announced today the publication of its 13C Isotopolome Wide Association Study matrix in the official journal of the Federation of American Societies for Experimental Biology in collaboration with scientists at the University Of Utah School Of Medicine.

6 Apr 2013

U-M to improve disease diagnosis through metabolic profiling

The University of Michigan Health System has earned a $9.1 million core grant from the National Institutes of Health to improve disease diagnosis through metabolic profiling.

8 Nov 2012

WCMC receives NHLBI grant to study smoking-induced COPD

Researchers at Weill Cornell Medical College were awarded a $6.5 million grant from the National Heart, Lung, and Blood Institute for a five-year investigation into metabolic changes occurring within airway epithelial cells in the lungs of chronic obstructive pulmonary disease (COPD) patients caused by cigarette smoking. In addition, researchers aim to identify which cigarette smokers are at highest risk of developing COPD as well as novel biomarkers to assist in the development of new therapeutic treatments for the disease.

17 Jul 2012

Metabolic profiling of tissue samples may transform the way surgeons make decisions

Metabolic profiling of tissue samples could transform the way surgeons make decisions in the operating theatre, say researchers at a new laboratory being launched today. Scientists at Imperial College London, in partnership with clinicians at Imperial College Healthcare NHS Trust, have installed a high resolution solid state nuclear magnetic resonance (NMR) spectrometer in St Mary's Hospital.

13 Jan 2011

New study says celiac disease patients should go on gluten-free diet

Findings from a new study of 141 adults add to an ongoing medical debate over which patients with symptoms of celiac disease should go on a gluten-free diet. Published in ACS' Journal of Proteome Research, the study concludes that people currently diagnosed as "potential" celiac disease patients and not advised to follow a gluten-free diet may not be "potential" patients at all. Rather, the scientists found that these patients have the same distinctive metabolic fingerprint as patients with full-blown disease who do benefit from gluten-free diets.

16 Dec 2010

Scientists develop first screening method to identify river blindness disease

Scientists from The Scripps Research Institute have developed the first screening method that rapidly identifies individuals with active river blindness, a parasitic disease that afflicts an estimated 37 million people. The test could change the current strategy of mass treatment in areas where river blindness, also known as onchocerciasis, is suspected.

7 Oct 2010

Blood test developed for non-alcoholic fatty liver disease diagnosis

Scientists at the Basque Center for Cooperative Research in Biosciences (CIC bioGUNE) and OWL Genomics Ltd. (Bilbao, Spain), in collaboration with researchers at the INSERM and University Hospitals (APHP Pitié Salpêtrière Hospital, Pierre & Marie Curie University Paris and Centre Hospitalier Universitaire Nice, University of Nice-Sophia-Antipolis, Nice, France), Vanderbilt University (Nashville, US), the University of Southern California (Los Angeles, US), Clinic Hospital and IDIBAPS (Barcelona, Spain) and the Alcalá de Henares University (Alcalá de Henares, Spain) have used metabolomics technology to develop a blood test for non-alcoholic fatty liver disease (NAFLD) diagnosis.

19 Sep 2010