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Small lipid nanocarrier may deliver chemotherapeutic drug more efficiently to brain tumor cells

Small lipid nanocarrier may deliver chemotherapeutic drug more efficiently to brain tumor cells

Great discoveries do come in small packages. Few know that better than Ann-Marie Broome, Ph.D., who feels nanotechnology holds the future of medicine with its ability to deliver powerful drugs in tiny, designer packages. [More]
ULK1, ULK2 enzymes play key role in maintaining cellular homeostasis

ULK1, ULK2 enzymes play key role in maintaining cellular homeostasis

Researchers at St. Jude Children's Research Hospital have uncovered how two enzymes, ULK1 and ULK2, which are best known for their role in the degradation and recycling of proteins, control the trafficking of specific proteins. [More]
Umea University researchers find link between vitamin E and brain tumours

Umea University researchers find link between vitamin E and brain tumours

Researchers at Umea University in Sweden and the Cancer Registry of Norway have studied possible causes behind the development of brain tumours. [More]
AKR1C3 enzyme could be promising therapeutic target for managing CRPC, AML

AKR1C3 enzyme could be promising therapeutic target for managing CRPC, AML

Prostate cancer is the second leading cause of mortality among American men with the highest incidence rate of all cancers reported in the U.S. Male sex hormones testosterone (T) and 5α-dihydrotestosterone (5α-DHT) promote prostate cancer progression. [More]
New study links altered purine metabolism to major depressive disorder

New study links altered purine metabolism to major depressive disorder

People suffering from major depressive disorder may have altered purine metabolism, according to a new study from the University of Eastern Finland and Kuopio University Hospital. [More]
Air-dried silk protein encapsulation can stabilize blood samples for long periods of time

Air-dried silk protein encapsulation can stabilize blood samples for long periods of time

Researchers at Tufts University have stabilized blood samples for long periods of time without refrigeration and at high temperatures by encapsulating them in air-dried silk protein. [More]
Repeat, low-dose ketamine infusions may quickly reduce suicidal thoughts in depressed outpatients

Repeat, low-dose ketamine infusions may quickly reduce suicidal thoughts in depressed outpatients

Repeat intravenous treatment with low doses of the anesthetic drug ketamine quickly reduced suicidal thoughts in a small group of patients with treatment-resistant depression. [More]
Studies show mango consumption may contribute to protective health effects

Studies show mango consumption may contribute to protective health effects

Four new studies surrounding the effects of mango consumption suggest this superfruit has the potential to help combat adverse effects associated with high fat diets and obesity (animal study), as well inhibit growth of fat cells (anti-lipogenic properties in an in-vivo study), slow advancement of breast cancer tumors (animal study), as well as improve regularity and decrease inflammation associated with constipation (human subject study). [More]
Fish oil supplements combined with anti-cancer therapy can reduce renal cell carcinoma

Fish oil supplements combined with anti-cancer therapy can reduce renal cell carcinoma

Researchers at UC Davis have shown that docosahexaenoic acid (DHA), a fatty acid commonly found in fish and fish oil supplements, reduces renal cell carcinoma invasiveness, growth rate, and blood vessel growth when combined with the anti-cancer therapy regorafenib. The study was published in the journal Molecular Cancer Therapeutics. [More]
Innovative strategy can reverse symptoms in neurodegenerative diseases

Innovative strategy can reverse symptoms in neurodegenerative diseases

Alzheimer's and Parkinson's disease are the two most common neurodegenerative disorders worldwide and cause untold suffering to millions of patients and their families. Treatments for these diseases are limited, and no cures exist. Now, a new study describes an innovative strategy that reverses symptoms in these neurodegenerative diseases - at least in fruit flies which had been genetically altered to model the diseases. [More]
University of Leicester-led study finds way to reverse symptoms of Parkinson’s and Alzheimer’s

University of Leicester-led study finds way to reverse symptoms of Parkinson’s and Alzheimer’s

A five-year study by an international team led from the University of Leicester has found a way of ‘reversing’ symptoms of neurodegenerative diseases such as Parkinson’s and Alzheimer’s – using fruit flies as test subjects. [More]
AMSBIO launches 96-Well CometChip System for high-throughput measurement of DNA damage

AMSBIO launches 96-Well CometChip System for high-throughput measurement of DNA damage

AMSBIO has announced the launch of the 96-Well CometChip System - a high-throughput platform developed to simultaneously treat and measure DNA damage induced by different treatments, or among different cell types on a single slide using the Comet assay. [More]
Sleep loss influences cholesterol metabolism, study finds

Sleep loss influences cholesterol metabolism, study finds

Lack of sleep has previously been found to impact the activation of the immune system, inflammation, carbohydrate metabolism and the hormones that regulate appetite. Now University of Helsinki researchers have found that sleep loss also influences cholesterol metabolism. [More]
NASA's research program uses omics to look more closely at individual health

NASA's research program uses omics to look more closely at individual health

NASA's Human Research Program is releasing the first half of a video series entitled Omics: Exploring Space Through You to highlight its Twins Study, in conjunction with its National DNA Day Reddit Ask Me Anything event at 10 a.m. CDT/11 a.m. EDT, Monday, April 25, 2016. The series explores space through you by using omics to look more closely at individual health. [More]
Bacteria-derived gut metabolites can affect brain’s myelin content and induce depression-like symptoms

Bacteria-derived gut metabolites can affect brain’s myelin content and induce depression-like symptoms

Specific combinations of gut bacteria produce substances that affect myelin content and cause social avoidance behaviors in mice, according to a study conducted at the Icahn School of Medicine at Mount Sinai and published today in the medical journal eLife. This research suggests that targeting intestinal bacteria, or their metabolites, could be one way to treat debilitating psychiatric disorders and demyelinating diseases, like multiple sclerosis. [More]
Using proteomics to understand Alzheimer’s: an interview with Dr Renã Robinson

Using proteomics to understand Alzheimer’s: an interview with Dr Renã Robinson

In our bioanalytical mass spectrometry lab we use proteomics techniques to try to understand more about Alzheimer's disease. The primary thrust of our research is that we're interested in understanding the changes that take place outside of the brain and how those correlate with what's taking place inside the brain [More]
Reclaimed wastewater irrigated crops expose consumers to minute quantities of anti-epileptic drug

Reclaimed wastewater irrigated crops expose consumers to minute quantities of anti-epileptic drug

A new study by a multidisciplinary team of researchers from the Hebrew University of Jerusalem and Hadassah Medical Center shows that eating vegetables and fruits grown in soils irrigated with reclaimed wastewater exposes consumers to minute quantities of carbamazepine, an anti-epileptic drug commonly detected in wastewater effluents. [More]
Intestinal bacteria can be used to reduce cancer risk, reveals UCLA study

Intestinal bacteria can be used to reduce cancer risk, reveals UCLA study

Researchers have shown that various types of intestinal bacteria might be factors in both causing and preventing obesity, and in other conditions and diseases. Now, a UCLA study suggests that it could also potentially be used to reduce the risk for some types of cancer. [More]
High–performance, cost-effective NMR solutions for the pharmaceutical and chemical industries

High–performance, cost-effective NMR solutions for the pharmaceutical and chemical industries

At the 57th Experimental Nuclear Magnetic Resonance Conference (www.enc-conference.org), Bruker is showcasing several innovative drug discovery, drug development and process control solutions for small molecule NMR characterization in the chemical and pharmaceutical industries. [More]
Altered metabolism of two essential amino acids helps drive development of glioblastoma

Altered metabolism of two essential amino acids helps drive development of glioblastoma

The altered metabolism of two essential amino acids helps drive the development of the most common and lethal form of brain cancer, according to a new study led by researchers at The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute. [More]
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