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New metabolic blood profile method could help predict breast cancer

New metabolic blood profile method could help predict breast cancer

According to the World Health Organization, breast cancer is the most common cancer in women both in the developed and less developed world, and in the long term the scientists hope that the new method will lead to better prevention and early treatment of the disease. [More]
Blueberries may be effective in treatment for PTSD

Blueberries may be effective in treatment for PTSD

Up to 8 percent of people in the U.S. suffer from post-traumatic stress disorder (PTSD) as the result of witnessing or being the victim of a traumatic event. People with PTSD have been in a situation in which they were at risk of death, serious injury or sexual violence or have seen first-hand loved ones faces such threats. They may experience flashbacks, emotional detachment and jumpiness, among other symptoms that affect their ability to function in everyday life. [More]
CNIO researchers describe presence of MDH2 gene mutations in hereditary neuroendocrine tumors

CNIO researchers describe presence of MDH2 gene mutations in hereditary neuroendocrine tumors

Researchers in the Hereditary Endocrine Cancer Group of the Spanish National Cancer Research Centre -- led by Alberto Cascón and Mercedes Robledo -- have described the presence of mutations in the MDH2 gene, in a family with very rare neuroendocrine tumours associated with a high hereditary component: pheochromocytomas and paragangliomas that affect the suprarenal and parathyroid glands (groups of chromaffin cells in the central nervous system), respectively. [More]
Metabolic imbalance can trigger respiratory diseases in early childhood

Metabolic imbalance can trigger respiratory diseases in early childhood

An imbalance in our metabolism can trigger inflammatory processes in the body and activate the immune system. In a recent study, published in the Journal of Allergy and Clinical Immunology, UFZ researchers have been able to show that this applies even to newborns and children under one year of age, and is correlated with the development of respiratory diseases in early childhood. [More]
New range of purified, soluble immunoreceptors announced by AMSBIO

New range of purified, soluble immunoreceptors announced by AMSBIO

AMSBIO has announced a new range of purified, soluble immunoreceptors involved in key signalling pathways. Together with new indoleamine 2,3-dioxygenase (IDO) assay kits these products that can be used to screen for inhibitors of protein-protein interaction, as well as neutralizing antibodies that serve as positive controls for inhibition. [More]
Transplanted regulatory T cells may help in controlling inflammatory diseases

Transplanted regulatory T cells may help in controlling inflammatory diseases

With a $2 million grant from the National Institutes of Health, a team of researchers - including Rensselaer Polytechnic Institute professor Juergen Hahn - will investigate the potential of using transplanted regulatory T cells (Tregs) to reduce inflammation in diseases like inflammatory bowel disease, which currently has no known viable treatment options. [More]
Researchers discover new metabolic mechanisms linked to macrophage polarization

Researchers discover new metabolic mechanisms linked to macrophage polarization

A group of researchers from Washington University in St. Louis, Agios Pharmaceuticals and ITMO University has discovered new metabolic mechanisms that regulate macrophage polarization - the unique ability of these immune cells to change their specialization depending on the required task. [More]
Scientists examine how substances at low concentrations may impact human health

Scientists examine how substances at low concentrations may impact human health

A public and scientific discussion is currently taking place focusing on the question whether substances at low concentrations may lead to health impairments in humans. For this reason, an increasing number of experimental studies to test such effects are currently conducted using different chemicals. [More]
Study shows fatigue pathways are more sensitive in patients with chronic fatigue syndrome

Study shows fatigue pathways are more sensitive in patients with chronic fatigue syndrome

The mechanism that causes high-performance athletes to "feel the burn" turns out to be the culprit in what makes people with chronic fatigue syndrome feel exhausted by the most common daily activities, new University of Florida Health research shows. [More]
New device can detect cyanide exposure within 70 seconds

New device can detect cyanide exposure within 70 seconds

A victim of cyanide poisoning can die within 30 minutes. The diagnostic test to determine cyanide exposure takes 24 hours. [More]
Researchers gain new insights into molecular mechanisms affected by weight gain

Researchers gain new insights into molecular mechanisms affected by weight gain

Until now there have been few molecular epidemiological studies regarding the effects of weight changes on metabolism in the general population. In a recent study conducted and funded within the framework of the Competence Network Obesity, researchers at the Institute of Epidemiology II at Helmholtz Zentrum München evaluated molecular data of the KORA study. [More]
MDC scientists identify new molecular signaling pathway that regulates placental development

MDC scientists identify new molecular signaling pathway that regulates placental development

During pregnancy, the mother supplies the fetus with nutrients and oxygen via the placenta. If placental development is impaired, this may lead to growth disorders of the embryo or to life-threatening diseases of the mother such as preeclampsia, a serious condition involving high blood pressure and increased urinary protein excretion. [More]
Blood gas testing: an interview with David Stein, PhD, CEO, Point of Care, Siemens Healthcare Diagnostics

Blood gas testing: an interview with David Stein, PhD, CEO, Point of Care, Siemens Healthcare Diagnostics

The industry term ‘blood gas testing’ has come to mean the accurate measurement and reporting of a wide menu of blood parameters, all on a single platform. [More]
People who quit smoking have improved metabolic effects, new study finds

People who quit smoking have improved metabolic effects, new study finds

People who quit smoking have improved metabolic effects, a new study finds. The results will be presented in a poster Thursday, March 5, at ENDO 2015, the annual meeting of the Endocrine Society in San Diego. [More]
Common antidepressant medications not helpful for people with mood, anxiety disorders

Common antidepressant medications not helpful for people with mood, anxiety disorders

Studies indicate that the majority of people with mood and anxiety disorders who receive the most commonly prescribed class of antidepressant medications, Selective Serotonin Reuptake Inhibitors or SSRI's, are not helped by these medications. SSRIs are designed to increase serotonin, a neurotransmitter in the brain that is key to maintenance of mood. [More]
New study shows association between BPA exposure and ASD in children

New study shows association between BPA exposure and ASD in children

A newly published study is the first to report an association between bisphenol-A (BPA), a common plasticizer used in a variety of consumer food and beverage containers, with autism spectrum disorder (ASD) in children. [More]
SCIEX and Labor Berlin Collaboration to Advance Forensic Testing

SCIEX and Labor Berlin Collaboration to Advance Forensic Testing

SCIEX announced today a research collaboration with Labor Berlin, the largest clinical laboratory in Germany, for the development of a hybrid Quadrupole Time-of-Flight (TOF) MS/MS reference library of relevant forensic chemical compounds [More]
Neuroprotective compounds can limit damage to the brain during ischemic stroke

Neuroprotective compounds can limit damage to the brain during ischemic stroke

In the 1990s, neuroscientists identified a class of drugs that showed promise in the area of stroke. NMDA receptor antagonists could limit damage to the brain in animal models of stroke. But one problem complicated testing the drugs in a clinical setting: the side effects included disorientation and hallucinations. [More]
Hair sample tests reveal underreported exposure to tobacco smoke among preemies with lung disease

Hair sample tests reveal underreported exposure to tobacco smoke among preemies with lung disease

Public health experts have long known that tobacco smoke exposure (TSE) can be harmful for children with bronchopulmonary dysplasia, a lung disease that often accompanies premature birth. [More]
Tobacco smoke exposure common among children with bronchopulmonary dysplasia

Tobacco smoke exposure common among children with bronchopulmonary dysplasia

Public health experts have long known that tobacco smoke exposure (TSE) can be harmful for children with bronchopulmonary dysplasia, a lung disease that often accompanies premature birth. [More]
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