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Targeting enzyme responsible for glucose metabolism halts tumor growth, say researchers

Targeting enzyme responsible for glucose metabolism halts tumor growth, say researchers

Cancer cells generate energy differently than normal cells, a characteristic that helps them to survive and metastasize. A major goal in the field of cancer metabolism is to find ways to overcome this survival advantage. [More]
Metabolon announces launch of fourth-generation metabolomics platform

Metabolon announces launch of fourth-generation metabolomics platform

Metabolon, Inc., a leader in metabolomics-driven biomarker discovery, announced today the launch of DiscoveryHD4, the company's fourth-generation metabolomics platform. [More]

AB Sciex launches immunosuppressants kit to improve health care

Every organ transplant patient in the world faces the potential danger of his/her body rejecting a new organ, such as a heart, kidney or liver. Immunosuppressant drugs are required to help prevent rejection. [More]

Aspartic acid in hippocampus may be biomarker for predicting occurrence of cognitive dysfunction

Postoperative cognitive dysfunction is the deterioration of cognitive performance after anesthesia and surgery, and manifests as impairments in short-term memory, concentration, language comprehension, and social integration skills. [More]
UT Southwestern professor honored with 2014 Norman Hackerman Award in Chemical Research

UT Southwestern professor honored with 2014 Norman Hackerman Award in Chemical Research

Dr. Benjamin P. Tu, associate professor of biochemistry at UT Southwestern Medical Center, was honored today with the 2014 Norman Hackerman Award in Chemical Research. Dr. Tu was recognized for innovative studies of once-unappreciated molecules that may someday improve treatments for cancer or conditions associated with aging. [More]
UMass Medical School students win 2014 Harold M. Weintraub Graduate Student Award

UMass Medical School students win 2014 Harold M. Weintraub Graduate Student Award

Colin Conine and Emma Watson, PhD students in the Graduate School of Biomedical Sciences (GSBS) at the University of Massachusetts Medical School, received the 2014 Harold M. Weintraub Graduate Student Award for research into the mechanisms governing epigenetic inheritance and the complex interactions between diet, gene expression and physiology. [More]

Scientists step in with new way to determine drug safety without using animals

As some countries and companies roll out new rules to limit animal testing in pharmaceutical products designed for people, scientists are stepping in with a new way to test therapeutic drug candidates and determine drug safety and drug interactions — without using animals. [More]
Study: Identifying biomarkers could lead to earlier detection of preeclampsia

Study: Identifying biomarkers could lead to earlier detection of preeclampsia

Identifying biomarkers could lead to earlier detection of preeclampsia, which in turn can lead to healthier mothers and children, according to a collaborative study from the Centre of Molecular Inflammation Research (CEMIR) and the MR Cancer Group at the Norwegian University of Science and Technology (NTNU). [More]
Researcher discover new chemical class that attacks two key cancer cell building block targets

Researcher discover new chemical class that attacks two key cancer cell building block targets

Imagine cutting down the growth of cancer cells at their earliest stages to halt tumor growth. Research conducted by leading cancer metabolism researchers at Stony Brook University, Paul M. Bingham, PhD, and Zuzana Zachar, PhD, is showing promise in this approach with their clinical investigation of a new class of compounds that disrupt cancer cell mitochondrial metabolism. [More]
Vitamin D boosts survival of breast cancer patients

Vitamin D boosts survival of breast cancer patients

Breast cancer patients with high levels of vitamin D in their blood are twice as likely to survive the disease as women with low levels of this nutrient, report University of California, San Diego School of Medicine researchers in the March issue of Anticancer Research. [More]
Metabolon agrees to provide biochemical profiling services to Human Longevity

Metabolon agrees to provide biochemical profiling services to Human Longevity

Metabolon, Inc., the world's leading commercial-stage metabolomics company, announces the signing of an agreement with newly-launched Human Longevity Inc., whereby Metabolon will provide biochemical profiling services to assist HLI in its mission to tackle diseases of aging by building the world's largest and most complete human genotype, microbiome and phenotype database. [More]

"Sprouted" garlic has more heart-healthy antioxidant activity than fresher, younger bulbs

"Sprouted" garlic - old garlic bulbs with bright green shoots emerging from the cloves - is considered to be past its prime and usually ends up in the garbage can. But scientists are reporting in ACS' Journal of Agricultural and Food Chemistry that this type of garlic has even more heart-healthy antioxidant activity than its fresher counterparts. [More]
New scientific blood analysis predicts short-term mortality in humans

New scientific blood analysis predicts short-term mortality in humans

The general state of a person's metabolism can be diversely illustrated with a new scientific blood analysis. With the aid of the analysis biomarkers predicting short-term mortality have now been discovered [More]
Scientists identify lung-damaging molecule in cystic fibrosis patients during symptom flare-ups

Scientists identify lung-damaging molecule in cystic fibrosis patients during symptom flare-ups

A molecule previously linked to lung injuries in factory workers producing microwave popcorn might play an important role in microbial infections of the lung suffered by people with cystic fibrosis (CF), according to a recent study led by San Diego State postdoctoral researcher Katrine Whiteson. [More]
Omega-3 fatty acids especially DHA may have even wider range of biological impacts, shows study

Omega-3 fatty acids especially DHA may have even wider range of biological impacts, shows study

A study of the metabolic effects of omega-3 fatty acids, especially DHA, concludes that these compounds may have an even wider range of biological impacts than previously considered, and suggests they could be of significant value in the prevention of fatty liver disease. [More]
New study examines factors that may lead to end stage renal disease

New study examines factors that may lead to end stage renal disease

About 33 percent of people with type 2 diabetes suffer kidney damage that progresses to end stage renal disease, at which point they require either dialysis or kidney transplantation. Scientists have thought that this kidney disease is driven by damage to the glomeruli, blood vessels in the kidney, which spill the protein albumin into the urine. Current treatments targeting the resulting "albuminuria" do not prevent kidney failure. [More]
Researchers explore possible effects that diet have on gene expression through epigenetic mechanisms

Researchers explore possible effects that diet have on gene expression through epigenetic mechanisms

In "Epigenetics: A New Link Between Nutrition and Cancer", a recent article from Nutrition and Cancer: An International Journal, a publication of Routledge, researchers explore the possible effects that diet can have on gene expression through epigenetic mechanisms. [More]
Crowdsourcing fungal metabolites with antitumor activity: an interview with Dr. Robert H. Cichewicz, University of Oklahoma

Crowdsourcing fungal metabolites with antitumor activity: an interview with Dr. Robert H. Cichewicz, University of Oklahoma

Fungi have played a large role in the development of many important drugs that are in wide use today. The most well-known of these are the penicillins. [More]

Researchers uncover new genetic clue that contributes to increased risk of type 2 diabetes

​An international team of researchers in Mexico and the United States has uncovered a new genetic clue that contributes to an increased risk of developing type 2 diabetes, particularly the elevated risk among Mexican and other Latin American populations. [More]
PAZ extracts may be useful option for improving plasma cholesterol profile

PAZ extracts may be useful option for improving plasma cholesterol profile

Health Enhancement Products, Inc., in conjunction with Wayne State University's Department of Nutrition and Food Science in the College of Liberal Arts and Sciences, announces the publication of a scientific article in the Journal of Nutrition & Metabolism, "ProAlgaZyme sub-fraction improves the lipoprotein profile of hypercholesterolemic hamsters, while inhibiting production of betaine, carnitine, and choline metabolites." [More]