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Non-coding RNAs play key role in maintaining proper balance between fighting infection and inflammation

Non-coding RNAs play key role in maintaining proper balance between fighting infection and inflammation

Special RNA molecules called long non-coding RNAs (lncRNAs) are key controllers for maintaining immune health when fighting infection or preventing inflammatory disorders, according to research led by Jorge Henao-Mejia, MD, PhD, an assistant professor of Pathology and Laboratory Medicine in the Perelman School of Medicine at the University of Pennsylvania. [More]
U-M study casts doubt on possible link between obesity and imbalance of microbes

U-M study casts doubt on possible link between obesity and imbalance of microbes

For people with weight problems, news headlines in recent years may have brought relief, as researchers studying the microscopic creatures inside our bodies reported possible links between obesity and an out-of-whack balance of microbes. [More]
Umbilical cells from babies of obese mothers show impaired expression of vital genes regulating metabolism

Umbilical cells from babies of obese mothers show impaired expression of vital genes regulating metabolism

Scientists have long known that infants born to women who are obese show higher risks of obesity, but they don't fully understand what boosts those risks. [More]
Seeds of tropical shrub guarana contain ten times more amount of catechins than green tea

Seeds of tropical shrub guarana contain ten times more amount of catechins than green tea

The millions of people who consume green tea all over the world benefit from the catechins it contains. [More]
Novel marine natural product appears to reduce pancreatic tumor size

Novel marine natural product appears to reduce pancreatic tumor size

Scientists at Florida Atlantic University's Harbor Branch Oceanographic Institute found that a deep-water marine sponge collected off of Fort Lauderdale's coast contains leiodermatolide, a natural product that has the ability to inhibit the growth of cancer cells as well as block cancer cells from dividing using extremely low concentrations of the compound. [More]
Treating metabolic abnormalities may improve symptoms in patients with treatment-resistant depression

Treating metabolic abnormalities may improve symptoms in patients with treatment-resistant depression

Identifying and treating metabolic deficiencies in patients with treatment-resistant depression can improve symptoms and in some cases even lead to remission, according to new research from the University of Pittsburgh School of Medicine published online today in the American Journal of Psychiatry. [More]
Pancreatic cancer cells find alternative source of nutrition to avoid starvation

Pancreatic cancer cells find alternative source of nutrition to avoid starvation

Pancreatic cancer cells avert starvation in dense tumors by ordering nearby support cells to supply them with an alternative source of nutrition. [More]
Study finds reduced activity of ACMSD enzyme in people with suicidal behavior

Study finds reduced activity of ACMSD enzyme in people with suicidal behavior

It is known that people who have attempted suicide have ongoing inflammation in their blood and spinal fluid. Now, a collaborative study from research teams in the U.S., Sweden and Australia published in Translational Psychiatry shows that suicidal patients have a reduced activity of an enzyme that regulates inflammation and its byproducts. [More]
Research finds differences in breast milk of women who gave birth to pre-term infants

Research finds differences in breast milk of women who gave birth to pre-term infants

About 7 percent of all Danish children are born prematurely. This is of significant im-portance not only to the child's development, but it also affects the mother's body that - unexpectedly - has to produce the necessary nutrition for the newborn baby. [More]
Study finds high rate of misuse of seizure and pain drug

Study finds high rate of misuse of seizure and pain drug

With increasing public attention to overdose deaths and misuse of prescription medications in the United States, researchers today presented the results of a new study looking at abuse and misuse of gabapentin, a medication used to treat seizures and relieve nerve pain often associated with shingles. [More]
Researchers identify biomarkers to improve prognosis of CKD

Researchers identify biomarkers to improve prognosis of CKD

Currently, there is no effective method to predict the prognosis of chronic kidney disease (CKD) patients. [More]
Retained metabolites may contribute to impaired cognitive function in kidney failure patients

Retained metabolites may contribute to impaired cognitive function in kidney failure patients

Retention of certain metabolites in the blood may contribute to cognitive impairment in patients with kidney failure, according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology. [More]
Breastfeeding leads to long-term metabolic changes in mothers, study shows

Breastfeeding leads to long-term metabolic changes in mothers, study shows

An interdisciplinary team of scientists at the Helmholtz Zentrum München has studied the metabolism of women with gestational diabetes after giving birth. [More]
New mass spectrometry imaging protocol allows analysis of metabolite composition of tissues

New mass spectrometry imaging protocol allows analysis of metabolite composition of tissues

In biomedical research, working with tissue samples is indispensable because it permits insights into the biological reality of patients, for example, in addition to those gained from Petri dishes and computer simulations. [More]
Rare antibiotic compound detected in fungi for first time

Rare antibiotic compound detected in fungi for first time

Besides mushrooms such as truffles or morels, also many yeast and mould fungi, as well as other filamentous fungi belong to the Ascomycota phylum. They produce metabolic products which can act as natural antibiotics to combat bacteria and other pathogens. Penicillin, one of the oldest antibiotic agents, is probably the best known example. [More]
Food chemists find garlic aroma in breast milk of women who have consumed garlic

Food chemists find garlic aroma in breast milk of women who have consumed garlic

Food chemists at Friedrich-Alexander-Universität Erlangen-Nürnberg have found that garlic aroma is evident in the breast milk of women who have consumed garlic. [More]
Study reveals problems encountered when trying to avoid plastic exposure

Study reveals problems encountered when trying to avoid plastic exposure

The well-known documentary "Plastic Planet" by Werner Boote starkly illustrates the dangers of plastic and synthetics for human beings and also shows how ubiquitous plastic is. [More]
Tiny micro-vesicle structures may help predict probability of developing Alzheimer's dementia

Tiny micro-vesicle structures may help predict probability of developing Alzheimer's dementia

Researchers at University of California San Diego School of Medicine say tiny micro-vesicle structures used by neurons and other cells to transport materials internally or dispose of them externally carry tell-tale proteins that may help to predict the likelihood of mild cognitive impairment (MCI) developing into full-blown Alzheimer's disease (AD). [More]
Study demonstrates role of leukocyte activation receptor CD69 in development of psoriasis

Study demonstrates role of leukocyte activation receptor CD69 in development of psoriasis

Scientists at the Centro de Investigaciones Cardiovasculares Carlos III have defined the key role of an immune-system receptor in the development of psoriasis, suggesting that it could serve as a therapeutic target for the control of this disease. [More]
AHR plays role in modulating the body's innate immune response to viral infections

AHR plays role in modulating the body's innate immune response to viral infections

A receptor, first known for its role in mediating the harmful effects of the environmental pollutant dioxin in our body, is now understood to play other important roles in modulating the innate immune response. [More]
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