Metastasis News and Research RSS Feed - Metastasis News and Research

Metastasis is the spread of cancer from one part of the body to another. A tumor formed by cells that have spread is called a “metastatic tumor” or a “metastasis.” The metastatic tumor contains cells that are like those in the original (primary) tumor. The plural form of metastasis is metastases
Natural compound could reduce risk of developing triple-negative breast cancer metastasis

Natural compound could reduce risk of developing triple-negative breast cancer metastasis

More than 100 women die from breast cancer every day in the United States. Triple-negative breast cancers, which comprise 15 to 20 percent of all breast tumors, are a particularly deadly type of breast disease that often metastasize to distant sites. [More]
Researchers investigate influence of surrounding tissue on formation and growth of tumor cells

Researchers investigate influence of surrounding tissue on formation and growth of tumor cells

Malignant melanoma is the fastest-growing type of cancer and the most fatal skin disease. [More]
RIT research explores impact of shear stress on cells moving through blood vessels

RIT research explores impact of shear stress on cells moving through blood vessels

How do cells and protein molecules respond to stress as they travel through blood vessels? Could resulting changes to these biological components impact how diseases are spread? [More]
Researchers uncover structure of cancer cell receptor protein that paves way for drug development

Researchers uncover structure of cancer cell receptor protein that paves way for drug development

A team of researchers from Case Western Reserve University School of Medicine has helped uncover the elusive structure of a cancer cell receptor protein that can be leveraged to fight disease progression. [More]
Stem cell research offers alternative view of cancer metastasis

Stem cell research offers alternative view of cancer metastasis

Stem cells are among the most energetically activated, migratory and proliferative sub-populations of tumour cells, according to observations by scholars at the Biomedical Research Centre at the University of Salford. [More]
Protein involved in pancreatic cancer development plays more complicated role, study finds

Protein involved in pancreatic cancer development plays more complicated role, study finds

A protein thought to fuel pancreatic cancer development plays a much more complicated role, a new study finds. [More]
Chemotherapy-induced senescent cells promote side effects and cancer relapse

Chemotherapy-induced senescent cells promote side effects and cancer relapse

Standard chemotherapy is a blunt force instrument against cancer - and it's a rare cancer patient who escapes debilitating side effects from systemic treatments that mostly affect dividing cells, both malignant and healthy, throughout the body. [More]
Epigenetic changes drive successful metastases of pancreatic cancer cells

Epigenetic changes drive successful metastases of pancreatic cancer cells

A multicenter team of researchers reports that a full genomic analysis of tumor samples from a small number of people who died of pancreatic cancer suggests that chemical changes to DNA that do not affect the DNA sequence itself yet control how it operates confer survival advantages on subsets of pancreatic cancer cells. [More]
Ludwig study uncovers ancient cellular response that underlies spread of aggressive skin cancer

Ludwig study uncovers ancient cellular response that underlies spread of aggressive skin cancer

Each day, more than 1,600 people die from cancer in the US, and 450 in the UK, mostly because the disease has spread beyond a stage when surgery is an effective cure and has become resistant to therapy. Despite decades of research, understanding why cancer cells become invasive has remained shrouded in mystery. [More]
MGH researchers identify protein that may protect tumor-initiating cells in breast cancer

MGH researchers identify protein that may protect tumor-initiating cells in breast cancer

Massachusetts General Hospital investigators have identified a protein that may play an essential role in maintaining a population of tumor-initiating cells (TICs) -- treatment-resistant cells responsible for cancer recurrence and metastasis -- in breast cancer, as well as a compound that appears to reduce the molecule's ability to protect TICs from the effects of chemotherapy. [More]
Researchers explore how metastatic pancreatic cancer gets ‘reprogrammed’ for optimal malignancy

Researchers explore how metastatic pancreatic cancer gets ‘reprogrammed’ for optimal malignancy

Metastatic pancreatic cancer -- cancer that has spread from the pancreas to other tissues and is responsible for most patient deaths -- changes its metabolism and is "reprogrammed" for optimal malignancy, according to new findings reported Jan. 16 in Nature Genetics. [More]
MUSC scientists design novel antibody-based therapy to fight against cancer

MUSC scientists design novel antibody-based therapy to fight against cancer

Scientists at the Medical University of South Carolina (MUSC) have designed an antibody-based therapy that could target the functions of TGF-beta that cause cancer [More]
Roswell Park researchers identify gene signatures that may help predict fatal prostate cancers

Roswell Park researchers identify gene signatures that may help predict fatal prostate cancers

Standard therapy for prostate cancer, the third-leading cause of cancer-related deaths in American men, is based on blocking androgens, the male sex hormones. [More]
Research findings may provide new treatment for prevention of cancer metastasis

Research findings may provide new treatment for prevention of cancer metastasis

Breast cancer metastasis, the process by which cancer spreads, may be prevented through the new use of a class of drugs already approved by the U.S. Food and Drug Administration. [More]
Drug that improves blood flow in damaged heart may be possible treatment option for TNBC

Drug that improves blood flow in damaged heart may be possible treatment option for TNBC

Researchers are looking at a drug once used to improve blood flow in damaged hearts in thousands of patients as a possible treatment option for triple negative breast cancer (TNBC). [More]
Targeting Legumain could be promising strategy for treatment of cancer

Targeting Legumain could be promising strategy for treatment of cancer

Legumain (LGMN), or asparaginyl endopeptidase, is a newly identified lysosomal cysteine protease. [More]
Columbia University Medical Center to evaluate Biocept's Target Selector platform to diagnose LM in breast cancer patients

Columbia University Medical Center to evaluate Biocept's Target Selector platform to diagnose LM in breast cancer patients

Biocept, Inc., a leading commercial provider of clinically actionable liquid biopsy tests designed to improve the outcomes of cancer patients, announces that Columbia University Medical Center will conduct a study to evaluate the clinical utility of the Company's Target Selector™ platform to diagnose leptomeningeal metastases (LM) in patients with breast cancer. [More]
IQWiG investigates benefit of biomarker tests to support decision on adjuvant chemotherapy

IQWiG investigates benefit of biomarker tests to support decision on adjuvant chemotherapy

The German Institute for Quality and Efficiency in Health Care (IQWiG) investigated the benefit of biomarker tests to support the decision for or against adjuvant systemic chemotherapy in certain breast cancer patients, that is, women with primary hormone receptor-positive, HER2-negative breast cancer and up to 3 affected lymph nodes. [More]
Fred Hutch’s new Evergreen Fund to promote commercialization of research into lifesaving therapies

Fred Hutch’s new Evergreen Fund to promote commercialization of research into lifesaving therapies

Fred Hutchinson Cancer Research Center announced its first-ever grants from its newly established Evergreen Fund to spur researchers' efforts to advance bold ideas toward creating or partnering with a commercial entity. [More]
New discovery could lead to effective drugs to prevent excessive lymphatic growth in cancer

New discovery could lead to effective drugs to prevent excessive lymphatic growth in cancer

Cancer cells spread to other sites in the body through promoting the growth of new 'roads' to travel on. [More]
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