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Good genes behaving badly behind type 1 diabetes

Investigators combing the genome in the hope of finding genetic variants responsible for triggering early-onset diabetes may be looking in the wrong place, new research at the Stanford University School of Medicine suggests.

31 Oct 2008

New strategy to treat human infections caused by the yeast Candida albicans

Researchers at Georgetown University Medical Center (GUMC) have successfully tested a genetic strategy designed to improve treatment of human infections caused by the yeast Candida albicans, ranging from diaper rash, vaginitis, oral infections (or thrush which is common in HIV/AIDS patients), as well as invasive, blood-borne and life-threatening diseases.

27 Oct 2008

Human rhinovirus found to manipulate genes

Sneezing, runny nose and chills? You might blame the human rhinovirus (HRV), which causes 30 to 50 percent of common colds. But in reality, it's not the virus itself but HRV's ability to manipulate your genes that is the true cause of some of the most annoying cold symptoms.

26 Oct 2008

Simple gene-based blood test, quicker, more accurate evaluation for cystic fibrosis

Researchers at National Jewish Health have identified a simple gene-based blood test that more accurately and quickly measures cystic fibrosis patients' response to therapy than current tests.

26 Oct 2008

Discovery of novel candidate gene for inflammatory bowel diseases

A study of Crohn's disease and ulcerative colitis in children has identified a gene that influences whether children get these diseases early in life, and points to a potential new target for treatment.

2 Sep 2008

FDA clears test that determines what type of cancer cells are present in a malignant tumor

The U.S. Food and Drug Administration has cleared for marketing a test that can help health care professionals determine what type of cancer cells are present in a malignant tumor.

31 Jul 2008

Shared gene expression alterations in schizophrenia and bipolar disorder

Both schizophrenia and bipolar disorder can be disabling conditions, and both present clinically with significant mood and psychotic symptoms. These two illnesses also share genetic variants that might be involved in the predisposition to both disorders.

17 Jul 2008

"Smothered" genes combine with mutations to yield poor out come in cancer patients

Johns Hopkins Kimmel Cancer Center researchers have identified a set of genes in breast and colon cancers with a deadly combination of traditional mutations and "smothered" gene activity that may result in poor outcomes for patients.

15 Jul 2008

Designer diet for prostate cancer

Eating one or more portions of broccoli every week can reduce the risk of prostate cancer, and the risk of localised cancer becoming more aggressive.

1 Jul 2008

Electrostatic-based RNA assays technique could revolutionize medical diagnostics

The dream of personalized medicine - in which diagnostics, risk predictions and treatment decisions are based on a patient's genetic profile - may be on the verge of being expanded beyond the wealthiest of nations with state-of-the-art clinics.

30 Jun 2008

AutoGenomics issued European patent for Human papillomavirus

AutoGenomics has announced that it has been issued a key European patent for Human papillomavirus.

19 Jun 2008

Researchers pinpoint gene mutations responsible for 10 percent of non-familial cases of schizophrenia

Scans of the genome of patients with schizophrenia have revealed rare spontaneous copy number mutations that account for at least 10 percent of the non-familial cases of the disease.

1 Jun 2008

Estrogen drives distinct, aggressive prostate cancer

Using a breakthrough technology, researchers led by a Weill Cornell Medical College scientist have pinpointed the hormone estrogen as a key player in about half of all prostate cancers.

28 May 2008

febit receives U.S. patent for microfluidic extraction method

febit today announced the receipt of US patent #7320862 on its microfluidic microarray-based method for extraction of DNA and RNA.

27 May 2008

Boost for cancer research in Leicestershire

A new approach to pain relief, investigation of a gene that triggers colorectal cancer and the prevention, early diagnosis and treatment of ovarian cancer are three research projects at the University of Leicester, which are to benefit from funding from the Leicestershire and Rutland charity Hope Against Cancer.

21 May 2008

Mapping of prostate cancer genes opens the door to new treatments

Genetic changes during the initiation and progression of prostate cancer have eluded scientists to date. Now for the first time researchers have identified a specific gene expression profile of prostate cancer stem cells, with important implications for future treatments.

19 May 2008

U.S. patent office grants re-examination of RNA splicing microarray patent on behalf of Jivan

Jivan Biologics, Inc. announced today that the United States Patent and Trademark Office has ordered the re-examination of U.S. Patent No. 6,881,571. The serial number for the reexamination is 90/009,017.

19 May 2008

Analysis of alcoholics' brains suggests treatment target

An analysis of brain tissue samples from chronic alcoholics reveals changes that occur at the molecular level in alcohol abuse - and suggests a potential treatment target, according to researchers from Wake Forest University School of Medicine.

2 May 2008

Small molecule nutlin-3a activates an important cancer suppressor gene

By activating a cancer suppressor gene, a small molecule called nutlin-3a can block cancer cell division, according to researchers at the National Cancer Institute (NCI), part of the National Institutes of Health.

1 May 2008

Biomarker predicts malignancy potential of HG-PIN lesions in the prostate

Men whose prostate cancer screenings show high grade prostatic intraepithelial neoplasia (HG-PIN) may find themselves in limbo, "stuck" between diagnoses - they are told prostate cancer has not yet developed, but it might, and they are advised to undergo repeated needle biopsies as a precaution.

1 May 2008