Microarray News and Research

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New test shows which breast cancers will recur

Approval has been granted by the FDA for a gene-based test that helps tell early-stage breast cancer patients whether they need chemotherapy after their surgery.

7 Feb 2007

FDA clears MammaPrint test for marketing

The Food and Drug Administration (FDA) has cleared for marketing a test that determines the likelihood of breast cancer returning within five to 10 years after a woman's initial cancer. It is the first cleared molecular test that profiles genetic activity.

6 Feb 2007

High throughput quantification of protein expression of cancer antigens in tissue microarray using quantum dot nanocrystals

In attempt to identify biological markers, or biomarkers, that can signal the presence of cancer and help oncologists determine the best course of therapy when cancer is present, teams of investigators are scouring stored tissue samples obtained from thousands of cancer patients.

4 Dec 2006

Gene expression and lung cancer prognosis

While there have been significant advances in the use of gene expression profiling to assess a cancer prognosis, a Mayo Clinic review and analysis of existing lung cancer studies shows that this technology has not yet surpassed the accuracy of conventional methods used to assess survival in lung cancer patients.

19 Nov 2006

DNA analysis could boost accuracy of thyroid tests

By fine-tuning "fine-needle aspiration" biopsies with a super-fast genetic microarray technology, a team of surgeons from NewYork-Presbyterian Hospital/Weill Cornell Medical Center in New York City says they can greatly enhance the accuracy of these tests.

14 Nov 2006

Muscle protein myosin VI involved in the development of prostate cancer

Researchers at the Johns Hopkins Kimmel Cancer Center have for the first time implicated the muscle protein myosin VI in the development of prostate cancer and its spread.

8 Nov 2006

Detecting rare microRNAs with gold nanoparticles

Over the past three years, numerous studies have shown that short pieces of single-stranded RNA, known as microRNAs, play a central role in the development of at least some cancers.

30 Oct 2006

Gene called Kibra plays an important role in memory

Researchers at the Translational Genomics Research Institute (TGen) have announced the discovery of a gene that plays a significant role in memory performance in humans.

20 Oct 2006

Why organs fail following massive trauma

Massive trauma, say from a sabertooth tiger attack, meant immediate death for the primitive human.

17 Oct 2006

Novel attachment method provides boost to biosensor development

A versatile method for attaching precise amounts of biomolecules and even cells to electrically conductive surfaces could lead to a new generation of nanoscale biosensors with broad applicability in cancer diagnostics and basic research.

9 Oct 2006

ExonHit licenses Merck rights to RNA splicing microarray patent

ExonHit Therapeutics S.A., a drug and diagnostic discovery company, has announced that Merck & Co., Inc. has been granted a non-exclusive license to rights for research only under Patent US 6,881,571.

11 Sep 2006

Mitochondrial DNA sequencing tool updated

High-tech laboratory tools, like computers, are often updated publicly as their analytical capabilities expand. In the September issue of the Journal of Molecular Diagnostics, NIH grantees report they have developed a second generation "lab on a silicon chip" called the MitoChip v2.0 that for the first time rapidly and reliably sequences all mitochondrial DNA.

30 Aug 2006

FluChip can spot bird flu in under 12 hours

Scientists in the United States have developed a new technology that reduces the time it takes to achieve a detailed diagnosis of avian flu, from one week or more down to less than 12 hours.

30 Aug 2006

New microchip enables quick diagnosis of flu strains

Scientists from the University of Colorado at Boulder and the Centers for Disease Control and Prevention (CDC) have developed a microchip-based test that may allow more labs to diagnose influenza infections and learn more about the viruses causing illness.

30 Aug 2006

A tissue marker of poor prognosis in clear cell renal cell carcinoma

The search for molecular markers that further advance our knowledge of the biology of renal cell carcinoma (RCC) and assist in evaluating the diagnosis and prognosis of patients remains the subject of intense investigation.

20 Aug 2006

Gene amplification links growth controlling pathway from Drosophila to human cancers

Researchers at Harvard Medical School (HMS) and Massachusetts General Hospital (MGH) have discovered a new cancer-promoting role for a gene potentially involved in breast, liver, and other kinds of cancers.

8 Aug 2006

DNA of human embryonic stem cells is chemically modified in a characteristic, predictable pattern

Embryonic stem cells are derived from embryos that are undergoing a period of intense cellular activity, including the chemical addition of methyl groups to specific DNA sequences in a process known as DNA methylation.

6 Aug 2006

Researchers identify how molecules of microRNA are responsible for the growth of blood vessels in a model for human colon cancer

The process, called angiogenesis, results in ability of ravenous cancer cells to recruit blood vessels and receive a steady supply of nutrients and oxygen.

4 Aug 2006

SRU Biosystems OK'd to conduct business

SRU Biosystems announces the United States District Court for the District of Delaware has resolved in SRU's favor a dispute over the content and scope of a permanent injunction order sought by Corning.

2 Aug 2006

First complete kit for whole genome amplification and labeling

Kreatech Biotechnology BV has announced the launch of the "Genome-pULSe, arrayCGH Whole Genome Amplification and Labeling Kit" the latest addition to their product portfolio for arrayCGH analysis.

24 Jul 2006