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Scientists identify biomarker strongly associated with aggressive breast cancer

Scientists identify biomarker strongly associated with aggressive breast cancer

Two Northwestern University scientists have identified a biomarker strongly associated with basal-like breast cancer, a highly aggressive carcinoma that is resistant to many types of chemotherapy. The biomarker, a protein called STAT3, provides a smart target for new therapeutics designed to treat this often deadly cancer. [More]
Research finds stronger weapon against leprosy and tuberculosis

Research finds stronger weapon against leprosy and tuberculosis

In many parts of the world, leprosy and tuberculosis live side-by-side. Worldwide there are approximately 233,000 new cases of leprosy per year, with nearly all of them occurring where tuberculosis is endemic. [More]
Human gut microbiota can influence susceptibility to Campylobacter infection

Human gut microbiota can influence susceptibility to Campylobacter infection

The specific composition of bacterial species in a person's gut may protect against or increase susceptibility to Campylobacter, the most common cause of human bacterial intestinal inflammation, according research published this week in mBio-, the online open-access journal of the American Society for Microbiology. [More]
Another threat lies in the spread of Chikungunya virus, say experts

Another threat lies in the spread of Chikungunya virus, say experts

While media attention has been focused recently on coronavirus cases in the Arabian peninsula and the Ebola outbreak in West Africa, experts note that another threat lies in the spread of Chikungunya fever, an illness that is transmitted by mosquitoes and can cause fever, joint and muscle pain, headaches, and rashes. While it does not often cause death, the symptoms can be severe and disabling, with no treatment available. [More]
New contact lens microbiology workshop aims at preventing Acanthamoeba keratitis

New contact lens microbiology workshop aims at preventing Acanthamoeba keratitis

The American Academy of Ophthalmology today announced a contact lens microbiology workshop on Sept. 12 aimed at preventing Acanthamoeba keratitis, a rare infection among contact lens wearers that causes severe eye pain, redness, light sensitivity and potential vision loss. [More]
WHO taps UTMB to lead emerging infectious disease vaccine efforts

WHO taps UTMB to lead emerging infectious disease vaccine efforts

The world experts on vaccine development at the University of Texas Medical Branch at Galveston have received an international designation acknowledging their unique niche in a sphere where research, government regulation and big pharma often collide. [More]
AEG-1 protein blocks effects of retinoic acid in leukemia and liver cancer

AEG-1 protein blocks effects of retinoic acid in leukemia and liver cancer

Retinoic acid is a form of vitamin A that is used to treat and help prevent the recurrence of a variety of cancers, but for some patients the drug is not effective. [More]
Ebola virus defeats attempts by interferon to block viral reproduction in infected cells

Ebola virus defeats attempts by interferon to block viral reproduction in infected cells

One of the human body's first responses to a viral infection is to make and release signaling proteins called interferons, which amplify the immune system response to viruses. [More]
Researchers discover new clue to understanding how TB medication attacks dormant TB bacteria

Researchers discover new clue to understanding how TB medication attacks dormant TB bacteria

Researchers at the Johns Hopkins Bloomberg School of Public Health say they have discovered a new clue to understanding how the most important medication for tuberculosis (TB) works to attack dormant TB bacteria in order to shorten treatment. [More]
Canadian government to donate experimental vaccine to combat Ebola virus

Canadian government to donate experimental vaccine to combat Ebola virus

The Honourable Rona Ambrose, Minister of Health, today announced that the Government of Canada will donate doses of an experimental Ebola vaccine developed by the Public Health Agency of Canada to the World Health Organization (WHO) in its role as an international coordinating body in responding to the ongoing Ebola outbreak in West Africa. [More]
CAP awards accreditation to The Children's Hospital of Philadelphia Pathology & Laboratory Medicine

CAP awards accreditation to The Children's Hospital of Philadelphia Pathology & Laboratory Medicine

The Accreditation Committee of the College of American Pathologists (CAP) has awarded accreditation to The Children's Hospital of Philadelphia Pathology & Laboratory Medicine, Philadelphia, Pennsylvania based on results of a recent on-site inspection as part of the CAP's Accreditation Programs. [More]
Researchers discover highly virulent, multidrug resistant form of pathogen in Ohio

Researchers discover highly virulent, multidrug resistant form of pathogen in Ohio

A team of clinician researchers has discovered a highly virulent, multidrug resistant form of the pathogen, Pseudomonas aeruginosa, in patient samples in Ohio. [More]
Injecting vaccine-like compound into mice effective in protecting from malaria

Injecting vaccine-like compound into mice effective in protecting from malaria

A study led by Johns Hopkins Bloomberg School of Public Health researchers found that injecting a vaccine-like compound into mice was effective in protecting them from malaria. [More]
GW researcher awarded grant to develop a model system to study PN infection

GW researcher awarded grant to develop a model system to study PN infection

According to a recent World Health Organization report of the leading causes of death worldwide, one-third of all deaths are due to infectious and parasitic diseases. There are currently no vaccines for parasitic nematode (PN), or worm infections in humans, and development of new drugs and vaccines will stall until researchers have a better understanding of PN biology. [More]
Researchers find that animal's ability to endure internal parasite strongly influences reproductive success

Researchers find that animal's ability to endure internal parasite strongly influences reproductive success

In the first evidence that natural selection favors an individual's infection tolerance, researchers from Princeton University and the University of Edinburgh have found that an animal's ability to endure an internal parasite strongly influences its reproductive success. [More]
Researchers plan to develop vaccine into a type of antibody serum therapy

Researchers plan to develop vaccine into a type of antibody serum therapy

By many estimates, an Ebola vaccine could be available in humans as early as next year. But will it be the right one? There are a number of vaccines in development and each is in a race to prove that it is most effective, safe and that it will protect the largest number of people. [More]
Gut microbiome analysis has potential to be a new tool for noninvasive colorectal cancer screening

Gut microbiome analysis has potential to be a new tool for noninvasive colorectal cancer screening

Analysis of the gut microbiome more successfully distinguished healthy individuals from those with precancerous adenomatous polyps and those with invasive colorectal cancer compared with assessment of clinical risk factors and fecal occult blood testing, according to data published in Cancer Prevention Research, a journal of the American Association for Cancer Research. [More]
PET-CT using FDG-labeled leucocytes may help in detecting infection in patients with acute pancreatitis

PET-CT using FDG-labeled leucocytes may help in detecting infection in patients with acute pancreatitis

A new study diagnosing infection in patients with pancreatic fluid collections may swiftly and accurately rule out active infection in the body. [More]
Scientists shed new light on why teenagers are susceptible to meningitis and septicaemia

Scientists shed new light on why teenagers are susceptible to meningitis and septicaemia

University of York scientists have shed new light on why teenagers and young adults are particularly susceptible to meningitis and septicaemia. [More]
Modulation of B cells may effectively treat symptoms of type 2 diabetes and periodontitis

Modulation of B cells may effectively treat symptoms of type 2 diabetes and periodontitis

Going to the dentist isn't fun for anyone, but for those with periodontal disease related to type 2 diabetes, a new research discovery may have them smiling. [More]