Mitochondria News and Research

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Researchers discover unique protein in malaria parasite that could be new drug target

Over a thousand people die from malaria every day. The disease is caused by a single-cell parasite (protozoan) that is transmitted by mosquitoes. Anti-malaria efforts currently focus on effective diagnostics, mosquito nets, insecticides and drugs.

18 Apr 2018

Study finds muscle complications among active young adults with Type 1 diabetes

A new study from McMaster and York universities has found that poor muscle health may be a complication of Type 1 diabetes, even among active twenty-somethings.

18 Apr 2018

Scientists find link between over-accumulation of mitochondrial iron and Huntington's disease

Scientists at the University of Wyoming have found that mice engineered to have Huntington's disease (HD) have an over-accumulation of iron in their mitochondria.

11 Apr 2018

Removal of single mitochondrial protein leads to severe inflammation

The link between mitochondria and inflammation is still unclear. But it is known is that, for example, the accumulation of defective mitochondria, which should have been removed, causes inflammation.

10 Apr 2018

Autofluorescence imaging evaluates cell metabolism and wound healing

Kyle Quinn, assistant professor of biomedical engineering at the University of Arkansas, has published a review highlighting recent advances in autofluorescence imaging and discussing its role in evaluating cell metabolism.

5 Apr 2018

New insights into 100-year-old mystery open novel possibilities for breast cancer treatment

New insights into how cancer cells fuel their growth are opening novel possibilities for cancer treatment. A team of researchers at Baylor College of Medicine and Roswell Park Comprehensive Cancer Center has identified a long sought after connection between how cancer cells use the sugar glucose to generate energy - the Warburg pathway - and cancer growth.

3 Apr 2018

Monash scientists discover how gonorrhea-causing superbug evades the immune system

Every year, more than 100 million people worldwide develop the sexually transmitted disease gonorrhea, with health consequences such as infertility, transmission of the disease to newborn babies, and increased risk of HIV infections. There has been a 63 percent rise in gonorrhea in Australia over the past five years.

30 Mar 2018

Research uncovers ways to slow down progression of neurodegenerative conditions

A new paper in Bioorganic & Medicinal Chemistry Letters talks about the mechanism of influence of methanofullerenoles on hyperpolarized mitochondria.

30 Mar 2018

Researchers highlight the need to reconsider mitochondrial replacement moratorium

Mothers with mitochondrial DNA mutations often give birth to children who face incurable and fatal illnesses. But a much-studied form of mitochondrial replacement could prevent the transmission of such diseases from mothers to children, researchers say.

28 Mar 2018

Scientists discover new family of promising silver-based anti-cancer drugs

A new family of very promising silver-based anti-cancer drugs has been discovered by researchers in South Africa. The most promising silver thiocyanate phosphine complex among these, called UJ3 for short, has been successfully tested in rats and in human cancer cells in the laboratory.

26 Mar 2018

Researchers uncover cause of rare childhood neurodegenerative disease

Neurology researchers investigating a rare but devastating neurological regression in infants have discovered the cause: gene mutations that severely disrupt crucial functions in mitochondria, the energy-producing structures within cells.

23 Mar 2018

TPP-related compounds selectively shut down cancer cells with little or no effect on healthy cells

SCIENTISTS seeking to make chemotherapies which are less harmful to cancer patients have reported "highly promising" results from a synthetic molecule called TPP.

21 Mar 2018

Researchers succeed in integrating artificial organelles into cells of living organism

For the first time, an interdisciplinary team from the University of Basel has succeeded in integrating artificial organelles into the cells of living zebrafish embryos.

20 Mar 2018

TSRI scientists discover new pathway to promote mitochondrial function during stress

Scientists at The Scripps Research Institute have discovered a new pathway in cells that promotes mitochondrial function during times of stress, a response that can guard against disease as we age.

15 Mar 2018

Researchers find specific cellular structures that orchestrate rapid immunologic memory

With every infection or vaccination, memory cells form that the body uses to remember the pathogen. This has been known for decades - but the structure of this cellular immunologic memory has previously proven impossible to pin down.

9 Mar 2018

Engineers develop optical tool that can read metabolism at subcellular resolution

Metabolic changes in cells can occur at the earliest stages of disease. In most cases, knowledge of those signals is limited, since we usually detect disease only after it has done significant damage. Now, a team led by engineers at Tufts University School of Engineering has opened a window into the cell by developing an optical tool that can read metabolism at subcellular resolution, without having to perturb cells with contrast agents, or destroy them to conduct assays.

9 Mar 2018

Researchers determine cause of difficult-to-control mitochondrial diseases

A Japanese research group has discovered that taurine is conjugated with mitochondrial transfer RNAs (tRNAs), small RNAs that decode genetic information, and that taurine deficiency in tRNA dramatically reduces both mitochondrial protein translation and impairs mitochondrial membrane integrity.

7 Mar 2018

Salk researchers uncover power switch for muscles

If you've ever wondered how strenuous exercise translates into better endurance, researchers at the Salk Institute may have your answer. In a study published in the journal Cell Reports on March 6, 2018, scientists in Ronald Evans' lab have shown that the protein ERRγ (ERR gamma) helps deliver many of the benefits associated with endurance exercise.

6 Mar 2018

Preventing metabolic exhaustion in immune cells could enhance effects of immunotherapy

If you're an immune cell gearing up to fight cancer, you'd better eat your breakfast. The tumor microenvironment is a harsh place, and tumor cells are ready to wear you out.

6 Mar 2018

Study uncovers new target in Parkinson’s disease

A new study has uncovered a relationship between the presence of Lewy bodies and neuronal cell death in Parkinson's disease.

6 Mar 2018

Mitochondria News and Research

Researchers discover unique protein in malaria parasite that could be new drug target

Study finds muscle complications among active young adults with Type 1 diabetes

Scientists find link between over-accumulation of mitochondrial iron and Huntington's disease

Removal of single mitochondrial protein leads to severe inflammation

Autofluorescence imaging evaluates cell metabolism and wound healing

New insights into 100-year-old mystery open novel possibilities for breast cancer treatment

Monash scientists discover how gonorrhea-causing superbug evades the immune system

Research uncovers ways to slow down progression of neurodegenerative conditions

Researchers highlight the need to reconsider mitochondrial replacement moratorium

Scientists discover new family of promising silver-based anti-cancer drugs

Researchers uncover cause of rare childhood neurodegenerative disease

TPP-related compounds selectively shut down cancer cells with little or no effect on healthy cells

Researchers succeed in integrating artificial organelles into cells of living organism

TSRI scientists discover new pathway to promote mitochondrial function during stress

Researchers find specific cellular structures that orchestrate rapid immunologic memory

Engineers develop optical tool that can read metabolism at subcellular resolution

Researchers determine cause of difficult-to-control mitochondrial diseases

Salk researchers uncover power switch for muscles

Preventing metabolic exhaustion in immune cells could enhance effects of immunotherapy

Study uncovers new target in Parkinson’s disease

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