Mitochondria News and Research

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Study identifies how excess fat disrupts heart cells' ability to produce energy

A University of Iowa study has identified how excess fat in the heart, a common feature in diabetes and obesity, can harm the cells' essential ability to produce energy.

5 Jan 2018

Soil-dwelling bacterium produces potential weapon against melanoma

A type of soil-dwelling bacterium produces molecules that induce death in melanoma cells, research at Oregon State University shows.

4 Jan 2018

Study finds new brainstem changes in Parkinson’s disease

A pioneering study has found that patients with Parkinson's disease have more errors in the mitochondrial DNA within the brainstem, leading to increased cell death in that area.

4 Jan 2018

UMSOM researchers identify new role for mitochondria in cocaine-induced behavior

For years, scientists have known that mitochondria in brain cells play a role in brain disorders such as depression, bipolar disorder, anxiety and stress responses.

20 Dec 2017

Antidepressant may also alleviate multiple sclerosis symptoms

The antidepressant clomipramine may also alleviate symptoms of multiple sclerosis (MS), specifically in its progressive form, i.e. when it occurs without relapses or remissions.

20 Dec 2017

Spatial deconvolution of marker expression in whole heart subjected to ischemia-reperfusion

When a coronary artery is obstructed by atheroma, blood flow is depressed or even arrested. This causes hypoxia of cardiac cells associated with the deprivation of nutrients. In clinic, the first objective is to restore blood flow. However, this is associated with a burst in oxidation of cellular proteins and lipids. This oxidation enhances cell death and participates to the so-called reperfusion injury.

From Logos Biosystems 18 Dec 2017

Mitochondrial error-correction mechanism essential for energy production of cells

Mitochondria generate most of the energy cells need through a respiratory chain for which they must produce their own proteins.

13 Dec 2017

Bipolar disorder may involve accelerated epigenetic aging, study finds

Bipolar disorder may involve accelerated epigenetic aging, which could explain why persons with the disorder are more likely to have - and die from - age-related diseases, according to researchers from The University of Texas Health Science Center at Houston.

12 Dec 2017

Study reveals novel molecular targets to improve chemotherapy’s efficiency against leukemia

Researchers from Instituto de Medicina Molecular João Lobo Antunes have found a mechanism through which certain types of leukemia resist chemotherapy, thus revealing novel molecular targets that may be used to improve the efficiency of this type of treatment.

12 Dec 2017

Reducing mitochondrial protein in cardiac muscle cells initiates heart failure

Reducing a protein found in the mitochondria of cardiac muscle cells initiates cardiac dysfunction and heart failure, a finding that could provide insight for new treatments for cardiovascular diseases, a study led by Georgia State University has shown.

6 Dec 2017

Scientists identify new strategies used by Helicobacter pylori to target mitochondria

Helicobacter pylori is a bacterial pathogen that colonizes the stomach of approximately half of the world's population. Infection with H. pylori is acquired in childhood and lasts for decades.

29 Nov 2017

Researchers explore new method of destroying tumor cells

Researchers from Lomonosov MSU Faculty of Biology have studied the stages of entosis, a process of cell death when one cell invades the other and gets digested inside of it. Entosis could become a new method of destroying cancer cells.

27 Nov 2017

Flies could act as autonomous bionic drones to help monitor disease outbreaks

An international research team led by Nanyang Technological University, Singapore have proposed that swarms of flies can be used to help monitor disease outbreaks.

25 Nov 2017

New study shows how SNO reaction may contribute to Parkinson's disease

A new study from The Scripps Research Institute is the first to show precisely how a process in nerve cells called the S-nitrosylation (SNO) reaction- which can be caused by aging, pesticides and pollution- may contribute to Parkinson's disease.

22 Nov 2017

Metabolites significantly affected in chronic kidney disease, study finds

Chronic kidney disease (CKD) affects 1 in 7 people in the United States, according to the U.S. National Institute of Diabetes & Digestive & Kidney Diseases.

22 Nov 2017

Leaf-eating ability of beetle largely due to bacteria inside the insect

A leaf-eating beetle has evolved a symbiotic relationship with bacteria that allows the insect to break down pectin -- part of a plant's cell wall that is indigestible to most animals.

17 Nov 2017

Compact broadband NIRS system offers safe, non-invasive way to monitor newborn brain function

Multimodal-Spectroscopy research team in the Biomedical Optics Research Laboratory at the Medical Physics and Biomedical Engineering department at University College London led by Dr IliasTachtsidis has designed CYRIL, a compact broadband near-infrared spectroscopy(NIRS) system, to monitor brain tissue physiology non-invasively in newborn babies.

15 Nov 2017

Early intervention may be crucial to successful treatment of Friedreich's ataxia

New research published today in Disease Models & Mechanisms indicates that early intervention should be a key target in the development of new therapeutics for Friedreich's ataxia, as current treatments may be administered too late to target the disease effectively.

8 Nov 2017

UNSW study examines effect of drug on negative effects of maternal obesity

A drug that increases energy metabolism may lead to a new approach to prevent obesity in children born to overweight mothers, UNSW Sydney researchers have found.