Mitochondria News and Research

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Researchers find link between disrupted energy production and late-onset Alzheimer's disease

A team of investigators from McLean Hospital and Harvard Medical School, led by Kai C. Sonntag, MD, PhD, and Bruce M. Cohen, MD, PhD, has found a connection between disrupted energy production and the development of late-onset Alzheimer's disease (LOAD). The findings appear in the current issue of Scientific Reports.

27 Oct 2017

Researchers discover mechanism that corrects protein misfolding in plants

Various human nervous system diseases, such as amyotrophic lateral sclerosis (ALS), Alzheimer's, Huntington's, and Parkinson's diseases, are associated with the same basic disorder: the loss of nerve cells capacity to fold their proteins correctly, which causes protein aggregations that form "clumps" that end up generating the cell death.

25 Oct 2017

Research identifies molecular mechanism that causes kidney cancer to resist drug treatment

New research from The University of Texas Health Science Center at San Antonio and U.S. Department of Veterans Affairs has identified the molecular mechanism that causes kidney cancer to resist drug treatment.

25 Oct 2017

New set of guidelines released for managing and caring patients with mitochondrial disease

Physicians who see patients with mitochondrial disease now have a practical new tool--a set of guidelines for managing and caring for those patients.

25 Oct 2017

Key enzyme may be therapeutic target to treat diabetes-related blood vessel damage

A key enzyme that helps our proteins fold and function properly may also be a good therapeutic target to improve blood vessel health in diseases like diabetes and atherosclerosis, scientists say.

23 Oct 2017

Study finds mitochondrial DNA damage in Veterans with Gulf War illness

Researchers say they have found the "first direct biological evidence" of damage in veterans with Gulf War illness to DNA within cellular structures that produce energy in the body.

19 Oct 2017

Synthetic compound targets enzyme that supports survival and dissemination of metastatic cells

Cancer can most often be successfully treated when confined to one organ. But a greater challenge lies in treating cancer that has metastasized, or spread, from the primary tumor throughout the patient's body.

17 Oct 2017

Researchers identify strategies to mitigate disturbed axonal transport in ALS patients

A team of researchers at VIB and KU Leuven used stem cell technology to generate motor neurons from ALS patients carrying mutations in FUS. They found disturbed axonal transport in these motor neurons, but also identified genetic and pharmacological strategies that mitigate this defect.

17 Oct 2017

Study helps understand basic mechanisms of mitochondrial DNA maintenance

Researchers at the University of Eastern Finland have discovered a novel mechanism safeguarding mitochondrial DNA. The study, published in PNAS earlier this week, was carried out in close collaboration with research groups from CBMSO in Madrid, Spain, and Umeå University in Sweden.

13 Oct 2017

USC discovery may one day lead to new therapies for liver cancer

A Keck School of Medicine of USC research team has identified how cancer stem cells survive. This finding may one day lead to new therapies for liver cancer, one of the few cancers in the United States with an incidence rate that continues to balloon.

12 Oct 2017

Mitochondrial DNA copy number appears to be predictive of sudden cardiac death, heart attacks

Johns Hopkins researchers report that the level, or "copy number," of mitochondrial DNA--genetic information stored not in a cell's nucleus but in the body's energy-creating mitochondria--is a novel and distinct biomarker that is able to predict the risk of heart attacks and sudden cardiac deaths a decade or more before they happen.

11 Oct 2017

Menopause causes metabolic changes in the brain that may increase Alzheimer's risk

Menopause causes metabolic changes in the brain that may increase the risk of Alzheimer's disease, a team from Weill Cornell Medicine and the University of Arizona Health Sciences has shown in new research.

10 Oct 2017

Newly discovered compound causes cancer cell death, whilst sparing healthy cells

Researchers have discovered a compound that can trigger cancer cells to self-destruct, without causing any damage to healthy cells.

10 Oct 2017

New treatment approach makes cancer cells commit suicide while sparing healthy cells

Scientists at Albert Einstein College of Medicine have discovered the first compound that directly makes cancer cells commit suicide while sparing healthy cells.

9 Oct 2017

Research explains why mTOR inhibitors show limited ability to kill cancer

Anti-cancer drugs called mTOR inhibitors slow the growth of cancer cells but show limited ability to cause cancer cell death. New studies explain why.

6 Oct 2017

New research uncovers how blood cancer 'steals' parts of bone marrow cells to thrive

New research published today uncovers how the blood cancer 'steals' parts of surrounding healthy bone marrow cells to thrive, in work that could help form new approaches to cancer treatment in the future.

5 Oct 2017

Medical treatment against diabetes reduces Parkinson’s disease risk

A Norwegian study shows that the taking of diabetes medicine reduces the risk of getting Parkinson´s disease.

25 Sep 2017

Researchers identify new genetic test to help predict cancer recurrence

Researchers have discovered a new genetic test which could help predict cancer recurrence - paving the way for more precise, personalized treatments.

21 Sep 2017

New device can monitor mitochondria in the heart to predict cardiac arrest

A new device can assess in real time whether the body's tissues are receiving enough oxygen and, placed on the heart, can predict cardiac arrest in critically ill heart patients, report researchers at Boston Children's Hospital and scientists from Cambridge device maker Pendar Technologies.

21 Sep 2017

Scientists find a way to convert “bad body fat” to “good fat”

Researchers have found that the unhealthy fat in the body called “white fat” could be converted to a healthier fat by blocking a special protein. This could help fight the obesity epidemic they speculate. The report was published in the journal Cell Reports.

19 Sep 2017

Mitochondria News and Research

Researchers find link between disrupted energy production and late-onset Alzheimer's disease

Researchers discover mechanism that corrects protein misfolding in plants

Research identifies molecular mechanism that causes kidney cancer to resist drug treatment

New set of guidelines released for managing and caring patients with mitochondrial disease

Key enzyme may be therapeutic target to treat diabetes-related blood vessel damage

Study finds mitochondrial DNA damage in Veterans with Gulf War illness

Synthetic compound targets enzyme that supports survival and dissemination of metastatic cells

Researchers identify strategies to mitigate disturbed axonal transport in ALS patients

Study helps understand basic mechanisms of mitochondrial DNA maintenance

USC discovery may one day lead to new therapies for liver cancer

Mitochondrial DNA copy number appears to be predictive of sudden cardiac death, heart attacks

Menopause causes metabolic changes in the brain that may increase Alzheimer's risk

Newly discovered compound causes cancer cell death, whilst sparing healthy cells

New treatment approach makes cancer cells commit suicide while sparing healthy cells

Research explains why mTOR inhibitors show limited ability to kill cancer

New research uncovers how blood cancer 'steals' parts of bone marrow cells to thrive

Medical treatment against diabetes reduces Parkinson’s disease risk

Researchers identify new genetic test to help predict cancer recurrence

New device can monitor mitochondria in the heart to predict cardiac arrest

Scientists find a way to convert “bad body fat” to “good fat”

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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