Mitochondria News and Research

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Stem Cell Educator therapy found to be safe and effective for treating diabetes

New research reveals that a treatment called Stem Cell Educator therapy is safe and effective for treating type 1 and type 2 diabetes. The therapy cultures the patient's immune cells with cord blood stem cells and returns only the "educated" immune cells to the patient's circulation.

7 Jul 2017

Mitochondria-targeted antioxidant shows promise for diabetic wound treatment

Members of the Faculty of Biology and A.N. Belozersky Institute of Physico-Chemical Biology, a unit of the Lomonosov Moscow State University, have tested on a mouse model a mitochondria-targeted antioxidant, helping to treat diabetic wounds.

29 Jun 2017

Scientists discover, count and determine new mitochondrial proteome in baker's yeast

Mitochondria, best known for their role as powerhouses of eukaryotic cells, fulfill numerous vital functions. Knowledge about the precise protein composition as well as the functions of individual proteins is essential to understand fundamental processes of cell biology and diseases that are caused by cellular defects.

29 Jun 2017

Study provides better knowledge about healthcare burden of mitochondrial diseases

Mitochondrial diseases are a diverse group of disorders caused by mutated genes that impair energy production in a patient's cells, often with severe effects.

28 Jun 2017

Mildly stressing muscle metabolism reverses diabetes and obesity in mice

Mildly stressing muscle metabolism boosts levels of a beneficial hormone that prevents obesity and diabetes in mice, according to a new study by researchers at the University of Iowa.

28 Jun 2017

Morgridge researchers reveal complex viral replication process in unprecedented detail

In the fight against the viruses that invade everyday life, seeing and understanding the battleground is essential. Scientists at the Morgridge Institute for Research have, for the first time, imaged molecular structures vital to how a major class of viruses replicates within infected cells.

27 Jun 2017

Could the mTOR pathway be used to protect against cancer?

The mTOR pathway is probably the main pathway in humans and other animals that drives growth. That is, the accumulation of mass and adding mass to make an organism bigger by both making more cells, and making cells grow and become bigger.

22 Jun 2017

Animal model of Gulf War illness hints at possible ways to mitigate symptoms

When hundreds of thousands of American troops deployed to the Persian Gulf in 1990 and 1991 in what is now called the First Gulf War, they were exposed to a variety of chemicals.

20 Jun 2017

Study shows how RNA splicing errors may trigger development of ALS, FTD

The most frequent genetic cause of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD)- rare and related neurological disorders marked by progressive deterioration of motor or cognitive abilities- may be due to errors in RNA splicing, an intermediary step for translating genetic instructions into functional proteins.

14 Jun 2017

Findings may contribute to better understanding of aging and cancer development

A team of researchers led by Dr. Dennis Kappei, a Special Fellow from the Cancer Science Institute of Singapore at the National University of Singapore, has discovered the role of the protein ZBTB48 in regulating both telomeres and mitochondria, which are key players involved in cellular aging.

14 Jun 2017

New one-two combination of antibiotics and Vitamin C could knock out cancer stem cells

CANCER stem cells, which fuel the growth of fatal tumors, can be knocked out by a one-two combination of antibiotics and Vitamin C in a new experimental strategy, published by researchers at the University of Salford, UK.

12 Jun 2017

Research reveals link between POMC neurons and release of insulin by the pancreas

The brain is key in the regulation of appetite, body weight and metabolism. Specifically, there is a small group of hypothalamus neurons, called POMC, that detect and integrate signals that inform on the energy state of the organism and activate the appropriate physiological responses.

8 Jun 2017

Studies offer hope for developing new biomarker and drug for neurodegenerative diseases

Two new studies of progressive, neurodegenerative diseases linked to defects in cells' mitochondria offer hope for developing a new biomarker for research and diagnostics, and a drug for treating such diseases, report researchers at the University of California, Davis.

6 Jun 2017

Scientists reveal 12-hour autonomous biological clock that coordinates bodily functions

Some bodily activities, sleeping, for instance, mostly occur once every 24 hours; they follow a circadian rhythm. Other bodily functions, such as body temperature, cognitive performance and blood pressure, present an additional 12-hour cycle, but little is known about the biological basis of their rhythm.

6 Jun 2017

Mouse model could improve understanding of human brown fat’s role in metabolic processes

When it gets cold around you, your body turns up the heat to maintain its normal temperature. The heat is produced by brown adipose tissue, or brown fat, which also plays a role in how the body uses glucose and fat.

2 Jun 2017

Clinical study tests 100-year-old drug in children with autism spectrum disorder

In a small, randomized Phase I/II clinical trial (SAT1), researchers at University of California San Diego School of Medicine say a 100-year-old drug called suramin, originally developed to treat African sleeping sickness, was safely administered to children with autism spectrum disorder (ASD), who subsequently displayed measurable, but transient, improvement in core symptoms of autism.

26 May 2017

Georgia State researchers renew $2.3 million federal grant for diabetic vascular disease research

Dr. Ming-Hui Zou, director of the Center for Molecular & Translational Medicine and a Georgia Research Alliance Eminent Scholar in Molecular Medicine, has renewed a four-year, $2.3 million federal grant to study the role of an enzyme in causing diabetic vascular diseases and the molecular mechanism that leads to these diseases.

25 May 2017